Control of synaptic function by endocannabinoid-mediated retrograde signaling [0.03%]
内源大麻素介导的逆行信号对突触功能的调节作用控制
Masanobu Kano
Masanobu Kano
Since the first reports in 2001, great advances have been made towards the understanding of endocannabinoid-mediated synaptic modulation. Electrophysiological studies have revealed that one of the two major endocannabinoids, 2-arachidonoylg...
Comprehensive whole-body counter surveys of Miharu-town school children for three consecutive years after the Fukushima NPP accident [0.03%]
福岛事故后三年来对美原町在校儿童进行全身计数器调查
Ryugo S Hayano,Masaharu Tsubokura,Makoto Miyazaki et al.
Ryugo S Hayano et al.
Comprehensive whole-body counter surveys covering over 93% of the school children between the ages of 6 and 15 in Miharu town, Fukushima Prefecture, have been conducted for three consecutive years, in 2011, 2012 and 2013. Although the resul...
Japanese cedar pollinosis: discovery, nomenclature, and epidemiological trends [0.03%]
日本扁柏花粉症：发现、命名及流行趋势分析
Yozo Saito
Yozo Saito
The history of pollinosis in Japan before the discovery of Japanese cedar pollinosis was presented in part I in this paper. Until early 1960s, it was believed that there was no pollinosis in Japan except one case of ragweed pollinosis. The ...
In vitro fertilization in Japan - early days of in vitro fertilization and embryo transfer and future prospects for assisted reproductive technology [0.03%]
日本的体外受精技术——体外受精与胚胎移植的早期发展及其辅助生殖技术的前景展望
Masakuni Suzuki
Masakuni Suzuki
Assisted reproductive technology (ART) such as in vitro fertilization (IVF) and embryo transfer (ET) has been essential in the treatment of infertility. The world's first IVF-ET baby was born in 1978 based on the technique developed by Dr. ...
Functional zonation of the rat adrenal cortex: the development and maintenance [0.03%]
大鼠肾上腺皮质的功能分割：发育和维持
Fumiko Mitani
Fumiko Mitani
The adrenal cortex of mammals consists of three concentric zones, i.e., the zona glomerulosa (zG), the zona fasciculata (zF), and the zona reticularis (zR), which secrete mineralocorticoids, glucocorticoids, and adrenal androgens, respectiv...
Emerging novel concept of chaperone therapies for protein misfolding diseases [0.03%]
针对蛋白质错误折叠疾病的新型分子伴侣治疗概念
Yoshiyuki Suzuki
Yoshiyuki Suzuki
Chaperone therapy is a newly developed molecular therapeutic approach to protein misfolding diseases. Among them we found unstable mutant enzyme proteins in a few lysosomal diseases, resulting in rapid intracellular degradation and loss of ...
Taroh Kinoshita
Taroh Kinoshita
At least 150 different human proteins are anchored to the outer leaflet of the plasma membrane via glycosylphosphatidylinositol (GPI). GPI preassembled in the endoplasmic reticulum is attached to the protein's carboxyl-terminus as a post-tr...
Ribosomal RNA gene repeats, their stability and cellular senescence [0.03%]
核糖体RNA基因重复序列的稳定性与细胞衰老的关系
Takehiko Kobayashi
Takehiko Kobayashi
The ribosomal RNA gene (rDNA) repeats form a historically well-researched region in the chromosome. Their highly repetitive structure can be identified easily which has enabled studies on DNA replication, recombination, and transcription. T...
Identification and quantification of amyloid beta-related peptides in human plasma using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry [0.03%]
利用基质辅助激光解析电离飞行时间质谱鉴定和定量人血浆中的淀粉样β肽
Naoki Kaneko,Rie Yamamoto,Taka-Aki Sato et al.
Naoki Kaneko et al.
Proteolytic processing of the amyloid precursor protein (APP) by β-secretase and γ-secretase leads to the generation and deposition of amyloid β (Aβ) in Alzheimer's disease (AD). N-terminally or C-terminally truncated Aβ variants have ...
Asymmetric shock heating and the terrestrial magma ocean origin of the Moon [0.03%]
不对称冲击加热与地球熔岩海洋起源月球理论
Shun-ichiro Karato
Shun-ichiro Karato
One of the difficulties of the current giant impact model for the origin of the Moon is to explain the marked similarity in the isotopic compositions and the substantial differences in the major element chemistry. Physics of shock heating i...