Pursuing the identity of a natural medicine licorice by Dr. Shoji Shibata that he firstly investigated half a century before [0.03%]
追寻半世纪前藤田昌一是首位调查的天然药物甘草的身份
Michiho Ito
Michiho Ito
This article is an explanatory review on a study of licorice stored in Shosoin Repository reported in this journal by Dr. Shoji Shibata in 2003 (Proc. Jpn. Acad. Ser. B 79, 176-180). The study using new technologies at that time for identif...
The shifting paradigm of chromatin structure: from the 30-nm chromatin fiber to liquid-like organization [0.03%]
染色质结构的转变观念：从30纳米纤维到类似液体的组织模式
Kazuhiro Maeshima
Kazuhiro Maeshima
The organization and dynamics of chromatin are critical for genome functions such as transcription and DNA replication/repair. Historically, chromatin was assumed to fold into the 30-nm fiber and progressively arrange into larger helical st...
Cellular senescence as a source of chronic microinflammation that promotes the aging process [0.03%]
细胞衰老成为慢性微炎症的来源并促进衰老过程
Makoto Nakanishi
Makoto Nakanishi
Why and how do we age? This physiological phenomenon that we all experience remains a great mystery, largely unexplained even in this age of scientific and technological progress. Aging is a significant risk factor for numerous diseases, in...
Common and distinct features of diverse macrophage populations in the central nervous system [0.03%]
中枢神经系统中各种巨噬细胞群的共同和独特特征
Takahiro Masuda
Takahiro Masuda
Tissue-resident macrophages perform indispensable functions in the development, maintenance, and repair of tissues. Microglia are the primary resident immune cells in the central nervous system (CNS), functioning as intracerebral macrophage...
The potential health risks of exposure to environmental chemicals - Global implications for future generations [0.03%]
环境化学物质暴露的潜在健康风险——对未来世代的全球影响
Reiko Kishi,Atsuko Ikeda,Rahel Mesfin Ketema
Reiko Kishi
In 2001, we launched the Hokkaido Study, the first prospective birth cohort study in Japan. We are currently tracking the effects of environmental chemicals, using a life course approach. The study examines life circumstances after birth, a...
Mechanism of puberulic acid contamination in red yeast rice tablets that caused a serious food poisoning outbreak in Japan [0.03%]
导致日本一起严重食物中毒事件的红曲米片中麦角酸污染机制研究
Tomoya Yoshinari,Maiko Watanabe,Wataru Aoki et al.
Tomoya Yoshinari et al.
In Japan, serious food poisoning among individuals who took supplement tablets for lowering plasma cholesterol levels have been publicized since late March 2024. The tablets were prepared from red yeast rice (RYR), a product of Monascus pil...
Conformational dynamics and molecular interactions of natural products: unveiling functional structures in biological membranes [0.03%]
天然产物的构象动力学和分子相互作用：揭示生物膜中的功能结构
Michio Murata,Masayuki Satake,Nobuaki Matsumori
Michio Murata
Structural studies of natural products have been a driving force in the development of organic chemistry throughout its long history, especially in the early years. Recently, structure determination based on new concepts has also gained mom...
Re-recognized universality of Kozai oscillation on three-body dynamics [0.03%]
Kozai振荡在三体动力学中的重新认识的普遍性
Masanori Iye,Takashi Ito
Masanori Iye
In 1962, Yoshihide Kozai reported his findings on the secular dynamics of asteroids moving in orbits with high inclination and eccentricity. In contrast to the classic understanding of the stability of planetary motion in the solar system, ...
Peaks in weak lensing mass maps for cluster astrophysics and cosmology [0.03%]
弱透镜质量图中的峰值在星系团天体物理学和宇宙学中的应用
Masamune Oguri,Satoshi Miyazaki
Masamune Oguri
Clusters of galaxies can be identified from the peaks in weak lensing aperture mass maps constructed from weak lensing shear catalogs. Such purely gravitational cluster selection differs considerably from traditional cluster selection based...
Salma E Said,Daisuke Miyamoto
Salma E Said
Over the past decades, the understanding of sleep has evolved to be a fundamental physiological mechanism integral to the processing of different types of memory rather than just being a passive brain state. The cyclic sleep substates, name...