Naoki Kaneko,Akinori Nakamura,Yukihiko Washimi et al.
Naoki Kaneko et al.
Alzheimer's disease (AD) is the most common and devastating dementia. Simple and practical biomarkers for AD are urgently required for accurate diagnosis and to facilitate the development of disease-modifying interventions. The subjects for...
Yoshiyuki Tatsumi,Keiko Suzuki-Kamata
Yoshiyuki Tatsumi
The Japanese Archipelago is characterized by active volcanism with variable eruption styles. The magnitude (M)-frequency relationships of catastrophic caldera-forming eruptions (M ≥ 7) are statistically different from those of smaller erup...
Kunihiko Saito
Kunihiko Saito
Since the phospholipase B (PLB) was reported as a deacylase of both lecithin and lysolecithin yielding fatty acids and glycerophosphocholine (GPC), there was a question as to whether it is a single enzyme or a mixture of a phospholipase A2 ...
Use of gnotobiotic mice to identify and characterize key microbes responsible for the development of the intestinal immune system [0.03%]
利用无特定病原体鼠鉴定和表征肠道免疫系统发育关键微生物的方法
Yoshinori Umesaki
Yoshinori Umesaki
Symbiosis between intestinal microbiota and the host animal plays an important role in the homeostasis of host physiology. Since the first production of germ-free rodents in 1945, it has become increasingly clear that the intestinal immune ...
Eiji Sato
Eiji Sato
Remarkable progress has recently been made in molecular biology of double axis formation in Xenopus laevis. Leaving aside, for the time being, the problem of the gene expressions regulating Xenopus laevis development, here I show that pulse...
Kenji Kosaka
Kenji Kosaka
In 1976 we reported our first autopsied case with diffuse Lewy body disease (DLBD), the term of which we proposed in 1984. We also proposed the term "Lewy body disease" (LBD) in 1980. Subsequently, we classified LBD into three types accordi...
Hideaki Miyata,Hideo Orihara,Yohei Sato
Hideaki Miyata
Research works undertaken in the first author's laboratory at the University of Tokyo over the past 30 years are highlighted. Finding of the occurrence of nonlinear waves (named Free-Surface Shock Waves) in the vicinity of a ship advancing ...
Satoshi Ide
Satoshi Ide
Earthquake sources represent dynamic rupture within rocky materials at depth and often can be modeled as propagating shear slip controlled by friction laws. These laws provide boundary conditions on fault planes embedded in elastic media. R...
Frontal affinity chromatography: a unique research tool for biospecific interaction that promotes glycobiology [0.03%]
frontal亲和色谱法:一种促进糖生物学研究的特有生物专一性交互工具
Kenichi Kasai
Kenichi Kasai
Combination of bioaffinity and chromatography gave birth to affinity chromatography. A further combination with frontal analysis resulted in creation of frontal affinity chromatography (FAC). This new versatile research tool enabled detaile...
Masahiro Asaka,Katsuhiro Mabe
Masahiro Asaka
In Japan, efforts have been directed toward improving the detection of early gastric cancer by double contrast radiography and endoscopy, since early cancer has a good prognosis, resulting in Japan having the world's best diagnostic system ...