Development of protein chemical synthesis using peptide thioester synthetic blocks [0.03%]
基于肽硫酯合成砌块的蛋白质化学合成的发展
Saburo Aimoto,Toru Kawakami,Hironobu Hojo
Saburo Aimoto
Emil Fischer was a pioneer in peptide chemistry, striving to elucidate the chemical nature of peptides and proteins. In 1901, he and his colleague published the first paper on the subject. Since then, peptide chemistry has advanced steadily...
A strategy to access unprecedented reactive intermediates featuring carbenes, carbocations, biradicals, and inverted σ-bonds via hypervalent λ3-haloganes [0.03%]
一种通过超价λ3-卤素化合物获得前所未有的含碳反应中间体的新策略
Kazunori Miyamoto,Masanobu Uchiyama
Kazunori Miyamoto
High-energy precursors can provide access to highly labile reactive intermediates, enabling unprecedented transformations under mild conditions. This review highlights a series of hypervalent λ3-haloganes, focusing on the λ3-iodanyl, λ3-...
Statistical and mechanical analysis of multi-pseudopodial locomotion in a testate amoeba, Arcella sp [0.03%]
固核型变形虫Arcella科的多伪足运动的统计学与力学分析
Genta Matsumoto,Atsushi Taniguchi,Mami Nomura et al.
Genta Matsumoto et al.
Adherent eukaryotic cells typically exhibit amoeboid locomotion through actin polymerization and bleb-driven mechanisms. However, testate amoebae, which enclose their bodies within a shell, exhibit variation in these locomotion types. This ...
Particulate photocatalysts for water splitting to produce green hydrogen on a large scale [0.03%]
大规模分解水制备绿色氢气的颗粒型光催化剂研究进展
Kazunari Domen
Kazunari Domen
Sunlight-driven overall water splitting using particulate photocatalysts is of growing interest as a means of producing green hydrogen from water, because systems based on particulate photocatalysts can be spread over large areas using pote...
Minoru Isobe
Minoru Isobe
Natural products that exhibit significant biological activity often possess complex molecular structures such as caged frameworks, strained motifs, inherent instability, and many stereogenic carbon centers, etc. Achievement of those total s...
Performance comparison of complementary relationship and inverse analysis methods for evapotranspiration estimation [0.03%]
互补关系与反算法估算蒸散发的对比研究
Toshisuke Maruyama,Manabu Segawa,Hiroshi Takimoto
Toshisuke Maruyama
Evapotranspiration is a critical factor that plays a pivotal role in irrigation and water resource planning. It is also a major influence with regard to global warming issues. Therefore, several studies have been performed on the estimation...
Development of phytochemical genomics: From decoding metabolome to functional genomics and biotechnology of plant metabolism [0.03%]
植物化学基因组学的发展：从解码代谢组到植物代谢的功能基因组学和生物技术
Kazuki Saito
Kazuki Saito
A characteristic feature of plants is their ability to produce a vast array of metabolites, a trait shaped by their evolution into sessile organisms. Over the past three decades, I have contributed to the development of phytochemical genomi...
Chemical properties and biological activities of three highly purified major tetrodotoxin analogues [0.03%]
三种高纯度河豚毒主要类似物的化学性质及其生物活性
Mari Yotsu-Yamashita,Yuta Kudo,Kyoka Sato et al.
Mari Yotsu-Yamashita et al.
Tetrodotoxin (TTX), the pufferfish toxin, has the potential to cause fatal food poisoning because of its potent voltage-gated sodium channel (Nav) blocking activity. 4-epiTTX, 11-norTTX-6(S)-ol, and 11-oxoTTX are the major TTX analogues fou...
Unconstrained deep learning-based sleep stage classification using cardiorespiratory and body movement activities in adults with suspected sleep apnea [0.03%]
基于无约束深度学习的睡眠分期算法及在成人阻塞型睡眠呼吸暂停综合征中的应用研究
Seiichi Morokuma,Toshinari Hayashi,Naoyuki Motomura et al.
Seiichi Morokuma et al.
This study assessed the feasibility of unconstrained deep-learning-based sleep stage classification using cardiorespiratory and body movement activities derived from piezoelectric sensors installed under a bed mattress. Heart and respirator...
Shun-Ichi Sekine
Shun-Ichi Sekine
Transcription is an essential biological process that underlies all cellular and organismal activities. In eukaryotes, RNA polymerase II (RNAPII) transcribes every protein-coding gene and many non-coding genes, playing a central role in gen...