Design of high-performance chiral phase-transfer catalysts with privileged structures [0.03%]
具有优势结构的高性能手性相转移催化剂的设计
Keiji Maruoka
Keiji Maruoka
In the end of the 20th century, due to various advantages of organocatalysis including environmental friendliness, operational simplicity, mild reaction conditions, easy recovery etc., had led to its recognition as a powerful strategy for t...
Diversity of ULBP5 in Old-World monkeys (Cercopithecidae) and divergence of the ULBP gene family in primates [0.03%]
旧大陆猴ULBP5的多样性及灵长类动物中ULBP基因家族的分化
Taeko K Naruse,Hirofumi Akari,Tetsuro Matano et al.
Taeko K Naruse et al.
Non-human primates such as rhesus macaque and cynomolgus macaque are important animals for medical research. These species are classified as Old-World monkeys (Cercopithecidae), in which the immune-related genome structure is characterized ...
Chemical kinetics study through observation of individual reaction events with atomic-resolution electron microscopy [0.03%]
基于原子分辨率电子显微镜的单反应事件观测的动力学研究
Eiichi Nakamura,Koji Harano
Eiichi Nakamura
Single-molecule atomic-resolution real-time electron microscopic movie imaging is an emerging new tool for obtaining dynamic structural information on molecules and molecular assemblies. This method provides a hitherto inaccessible possibil...
Current perspectives on autoimmune pancreatitis and IgG4-related disease [0.03%]
自身免疫性胰腺炎和IgG4相关疾病的当前观点
Kazuichi Okazaki,Kazushige Uchida
Kazuichi Okazaki
IgG4-related disease (IgG4-RD) is a fibroinflammatory disorder recognized as a novel clinical entity with either synchronous or metachronous multi-organ involvement. Patients with IgG4-RD show diffuse or focal organ enlargement and mass-for...
Diversity of structure and function of GABAB receptors: a complexity of GABAB-mediated signaling [0.03%]
GABA受体B型亚单位的功能和结构多样性：复杂的GABA_B介导信号系统
Miho Terunuma
Miho Terunuma
γ-aminobutyric acid type B (GABAB) receptors are broadly expressed in the nervous system and play an important role in neuronal excitability. GABAB receptors are G protein-coupled receptors that mediate slow and prolonged inhibitory action...
Yutaka Yatomi,Makoto Kurano,Hitoshi Ikeda et al.
Yutaka Yatomi et al.
Lysophospholipids (LPLs), such as lysophosphatidic acid (LPA), sphingosine 1-phosphate (S1P), and lysophosphatidylserine (LysoPS), are attracting attention as second-generation lipid mediators. In our laboratory, the functional roles of the...
Evolutionary history of carabid ground beetles with special reference to morphological variations of the hind-wings [0.03%]
基于后翅形态变异的虎甲 beetle 的进化历史研究
Yûki Imura,Osamu Tominaga,Zhi-Hui Su et al.
Yûki Imura et al.
Most beetles belonging to the subfamily Carabinae of the family Carabidae (so-called carabid ground beetles) cannot fly, because their hind-wings are highly degenerated. However, about half of the species in the subtribe Calosomina within t...
Studies on single-molecule bridging metal electrodes: development of new characterization technique and functionalities [0.03%]
单分子桥接金属电极研究：新表征技术及特性的开发
Manabu Kiguchi
Manabu Kiguchi
A single molecular junction is a nanoscale structure prepared by bridging a single molecule between macroscopic metal electrodes. It has attracted significant attention due to its unique structure and potential applications in ultra-small s...
Cytoskeletal control of nuclear migration in neurons and non-neuronal cells [0.03%]
细胞骨架控制神经元和非神经元细胞中的核迁移
Mineko Kengaku
Mineko Kengaku
Cell migration is a complex molecular event that requires translocation of a large, stiff nucleus, oftentimes through interstitial pores of submicron size in tissues. Remarkable progress in the past decade has uncovered an ever-increasing a...
Shun Koizumi,Jun Hamazaki,Shigeo Murata
Shun Koizumi
The 26S proteasome is a large protease complex that selectively degrades ubiquitinated proteins. It comprises 33 distinct subunits, each of which differ in function and structure, and which cannot be substituted by the other subunits. Owing...