Cellular senescence as a source of chronic microinflammation that promotes the aging process [0.03%]
细胞衰老成为慢性微炎症的来源并促进衰老过程
Makoto Nakanishi
Makoto Nakanishi
Why and how do we age? This physiological phenomenon that we all experience remains a great mystery, largely unexplained even in this age of scientific and technological progress. Aging is a significant risk factor for numerous diseases, in...
Common and distinct features of diverse macrophage populations in the central nervous system [0.03%]
中枢神经系统中各种巨噬细胞群的共同和独特特征
Takahiro Masuda
Takahiro Masuda
Tissue-resident macrophages perform indispensable functions in the development, maintenance, and repair of tissues. Microglia are the primary resident immune cells in the central nervous system (CNS), functioning as intracerebral macrophage...
The potential health risks of exposure to environmental chemicals - Global implications for future generations [0.03%]
环境化学物质暴露的潜在健康风险——对未来世代的全球影响
Reiko Kishi,Atsuko Ikeda,Rahel Mesfin Ketema
Reiko Kishi
In 2001, we launched the Hokkaido Study, the first prospective birth cohort study in Japan. We are currently tracking the effects of environmental chemicals, using a life course approach. The study examines life circumstances after birth, a...
Mechanism of puberulic acid contamination in red yeast rice tablets that caused a serious food poisoning outbreak in Japan [0.03%]
导致日本一起严重食物中毒事件的红曲米片中麦角酸污染机制研究
Tomoya Yoshinari,Maiko Watanabe,Wataru Aoki et al.
Tomoya Yoshinari et al.
In Japan, serious food poisoning among individuals who took supplement tablets for lowering plasma cholesterol levels have been publicized since late March 2024. The tablets were prepared from red yeast rice (RYR), a product of Monascus pil...
Conformational dynamics and molecular interactions of natural products: unveiling functional structures in biological membranes [0.03%]
天然产物的构象动力学和分子相互作用：揭示生物膜中的功能结构
Michio Murata,Masayuki Satake,Nobuaki Matsumori
Michio Murata
Structural studies of natural products have been a driving force in the development of organic chemistry throughout its long history, especially in the early years. Recently, structure determination based on new concepts has also gained mom...
Re-recognized universality of Kozai oscillation on three-body dynamics [0.03%]
Kozai振荡在三体动力学中的重新认识的普遍性
Masanori Iye,Takashi Ito
Masanori Iye
In 1962, Yoshihide Kozai reported his findings on the secular dynamics of asteroids moving in orbits with high inclination and eccentricity. In contrast to the classic understanding of the stability of planetary motion in the solar system, ...
Peaks in weak lensing mass maps for cluster astrophysics and cosmology [0.03%]
弱透镜质量图中的峰值在星系团天体物理学和宇宙学中的应用
Masamune Oguri,Satoshi Miyazaki
Masamune Oguri
Clusters of galaxies can be identified from the peaks in weak lensing aperture mass maps constructed from weak lensing shear catalogs. Such purely gravitational cluster selection differs considerably from traditional cluster selection based...
Salma E Said,Daisuke Miyamoto
Salma E Said
Over the past decades, the understanding of sleep has evolved to be a fundamental physiological mechanism integral to the processing of different types of memory rather than just being a passive brain state. The cyclic sleep substates, name...
Relationship between typical fall patterns and fall-related fractures in older Japanese adults [0.03%]
日本老年人典型跌倒姿势与跌伤骨折的关系
Minoru Yamada,Yusuke Terao,Iwao Kojima et al.
Minoru Yamada et al.
This study explored the relationship between fall patterns and fall-related fractures in older adults. A cross-sectional survey was conducted among community-dwelling older adults in Maibara City, Japan, focusing on falls over the past thre...
Pathogenesis of type 2 diabetes in Japan and East Asian populations: Basic and clinical explorations [0.03%]
日本及东亚人群2型糖尿病的发病机制：基础和临床探索
Yutaka Seino,Yuji Yamazaki
Yutaka Seino
It is now accepted that the pathogenesis of type 2 diabetes in East Asians including Japanese differs distinctly from that in Caucasians. Many non-obese individuals in Japan develop type 2 diabetes and present clinically with insufficient i...