Classification of Cutibacterium acnes at phylotype level by MALDI-MS proteotyping [0.03%]
飞行基因型水平上利用基质辅助激光解析电离飞行时间质谱对痤疮丙酸杆菌的分类研究
Kanae Teramoto,Tatsuki Okubo,Yoshihiro Yamada et al.
Kanae Teramoto et al.
Cutibacterium acnes is a major commensal human skin bacteria. It is a producer of propionic acids that maintain skin acidic pH to inhibit the growth of pathogens. On the other hand, it is also associated with diseases such as acne vulgaris ...
Cupid and Psyche system for the diagnosis and treatment of advanced cancer [0.03%]
用于晚期癌症诊断和治疗的丘比特与赛姬系统
Akira Sugiyama,Takeshi Kawamura,Toshiya Tanaka et al.
Akira Sugiyama et al.
In advanced cancer patients, malignant cells invade and disseminate within normal cells and develop resistance to therapy with additional genetic mutations, which makes radical cure very difficult. Precision medicine against advanced cancer...
"Dynamic" molecular recognition and chirality segregation utilizing concepts of molecular machines and molecular assemblies [0.03%]
利用分子机器和分子组装概念实现动态分子识别及手性分离
Seiji Shinkai
Seiji Shinkai
The need to measure the concentration of selected ions and small organic molecules in both in vivo and in vitro processes is continuously increasing beyond the borders of various research fields. This need has been fulfilled using "host-gue...
Masato Kasuga
Masato Kasuga
Immunoprecipitation with autoantibodies to the insulin receptor derived from patients with extreme insulin resistance and acanthosis nigricans revealed that the receptor is comprised of two subunits of 135 kDa (α subunit) and 95 kDa (β su...
Dynamic performance of bracket complexes used in traditional timber structures in Japan [0.03%]
日本传统木结构中挂件节点的动力性能研究
Kaori Fujita
Kaori Fujita
A bracket complex is a type of bearing system located on the top of a column and transmits the vertical load of the roof to the column. Bracket complexes are often used in Buddhist temples and Shinto shrines constructed using traditional ti...
Translational science: Newly emerging science in biology and medicine - Lessons from translational research on the natriuretic peptide family and leptin [0.03%]
转化医学：生命科学和医学中一门新出现的学科——从钠尿肽家族和瘦素研究中的经验教训
Kazuwa Nakao
Kazuwa Nakao
Translation is the process of turning observations in the laboratory, clinic, and community into interventions that improve the health of individuals and the public, ranging from diagnostics and therapeutics to medical procedures and behavi...
Takashi Nishikaze
Takashi Nishikaze
Mass spectrometry (MS) is a well-accepted means for analyzing glycans. Before glycan analysis by MS, several chemical derivatizations are generally carried out. These are classified into three categories; (1) labeling of the reducing end of...
A half century of infrared astronomy - A personal recollection of the footprints in Japan [0.03%]
红外天文学的半个世纪回顾——日本红外线观测半个世纪的日积月累与我自身的回忆
Haruyuki Okuda
Haruyuki Okuda
Since the new era of infrared astronomy was opened by the Two Micron Sky Survey by Neugebauer et al. in the early 1960s, about a half century has passed. During this time, observations have expanded rapidly and widely, to almost every field...
Intermediate filaments and IF-associated proteins: from cell architecture to cell proliferation [0.03%]
中间纤维和中间纤维相关蛋白：从细胞结构到细胞增殖
Yuhei Nishimura,Kousuke Kasahara,Masaki Inagaki
Yuhei Nishimura
Intermediate filaments (IFs), in coordination with microfilaments and microtubules, form the structural framework of the cytoskeleton and nucleus, thereby providing mechanical support against cellular stresses and anchoring intracellular or...
Yuki Sato,Motoko Yanagita
Yuki Sato
Chronic kidney disease (CKD) is a global public health problem, affecting over 10% of the world's population and more than half of the population aged over 70 years, imposing major costs on healthcare systems. Although the primary causes of...