Nano-scale analyses of the chromatin decompaction induced by histone acetylation [0.03%]
组蛋白乙酰化诱导的染色质解压缩的纳米分析方法研究进展
Kohji Hizume,Sumiko Araki,Kosuke Hata et al.
Kohji Hizume et al.
The acetylation of histone tails is a key factor in the maintenance of chromatin dynamics and cellular homeostasis. The hallmark of active chromatin is the hyper-acetylation of histones, which appears to result in a more open chromatin stru...
Scale and tooth phenotypes in medaka with a mutated ectodysplasin-A receptor: implications for the evolutionary origin of oral and pharyngeal teeth [0.03%]
牙盘素-A受体突变型刺尾鱼的齿和鳞片表型及其对口腔和咽牙齿的进化起源的意义
A D S Atukorala,Keiji Inohaya,Otto Baba et al.
A D S Atukorala et al.
Ectodermal contribution to the induction of pharyngeal teeth that form in the endodermal territory of the oropharyngeal cavity in some teleost fishes has been a matter of considerable debate. To determine the role of ectodermal cell signali...
Recruited peripheral blood monocytes participate in the liver extramedullary hematopoietic milieu [0.03%]
募集的外周血单核细胞参与肝脏体外造血微环境
Ayako Nakamura-Ishizu,Shunichi Morikawa,Kazuhiko Shimizu et al.
Ayako Nakamura-Ishizu et al.
The hematopoietic microenvironment has been investigated and well defined in the bone marrow. However, there is a lack of studies on the extramedullary hematopoietic milieu such as in the liver, to which hematopoietic stem cells migrate and...
Rapid three-dimensional analysis of renal biopsy sections by low vacuum scanning electron microscopy [0.03%]
低真空中子探针扫描电镜快速分析肾活检病理标本
Sumire Inaga,Masako Kato,Sayuri Hirashima et al.
Sumire Inaga et al.
Renal biopsy paraffin sections were examined by low vacuum scanning electron microscopy (LVSEM) in the backscattered electron (BSE) mode, a novel method for rapid pathological analysis which allowed detailed and efficient three-dimensional ...
A histomorphologic study of the normal healing response following digit amputation in C57bl/6 and MRL/MpJ mice [0.03%]
C57BL/6和MRL/mpj小鼠断趾术后正常修复反应的组织病理学研究
Neill J Turner,Scott A Johnson,Stephen F Badylak
Neill J Turner
Mice are common models for the study of mammalian wound healing. However, the array of available phenotypes suggests that significant differences likely exist in the normal wound healing response between different mouse strains. It is there...
Neurocan contributes to the molecular heterogeneity of the perinodal ECM [0.03%]
神经粘连蛋白参与结间体细胞外基质分子异质性构建
Yoko Bekku,Toshitaka Oohashi
Yoko Bekku
Neurocan is a central nervous tissue-specific chondroitin sulfate proteoglycan of the lectican family. Mainly expressed during modeling and remodeling stages of this tissue, it is thought to play an important role via binding to various ext...
Fixation conditions affect the immunoreactivity of gustducin in rat vallate taste buds [0.03%]
固定条件影响味蕾中味觉受体蛋白的功能状态
Maiko Haga,Sumio Yoshie
Maiko Haga
This study aimed to examine gustducin immunoreactivities when adopting various immunostaining conditions in rat vallate taste buds. The occurrence and intensity of the immunoreactivities exhibited specific patterns in accordance with the fi...
The acid-sensing ion channel 2 (ASIC2) of ciliated cells in the developing rat nasal septum [0.03%]
发育大鼠鼻中隔纤毛细胞的酸敏感离子通道2(ASIC2)
Shin Kikuchi,Takafumi Ninomiya,Tomoyuki Kawamata et al.
Shin Kikuchi et al.
The airway epithelium is exposed to an acidic environment in certain conditions. The acid-sensing ion channel 2 (ASIC2) belongs to the epithelial amiloride-sensitive sodium channel and degenerin (ENaC/DEG) family and is expressed on cilia o...
Hypothermic and normothermic ischemia-reperfusion activate microglia differently in hippocampal formation [0.03%]
低温与常温下缺血再灌注诱发海马小胶质细胞活化差异性研究
Anzu Yamashita,Teruhito Kunimatsu,Kentaro Yamada et al.
Anzu Yamashita et al.
Using immunohistochemical methods, we investigated microglial profiles under normothermic ischemia and hypothermic ischemia using an anti-ionized calcium-binding adapter molecule 1 (Iba-1) antibody. In the early stages of ischemia-reperfusi...
PKH26 is an excellent retrograde and anterograde fluorescent tracer characterized by a small injection site and strong fluorescence emission [0.03%]
PKH26是一种优良的逆行和顺行荧光示踪剂，具有极小注射体积和强荧光信号等优点
Koji Kawaguchi,Yu Katsuyama,Satoshi Kikkawa et al.
Koji Kawaguchi et al.
The fluorescent dye PKH26, which binds mainly to the cell membrane, has long stability that enables the tracing of PKH26-labeled transplanted cells in host tissue. In the present study, we examined whether this fluorescent dye works as a re...