Palopegteriparatide in Japanese adults with hypoparathyroidism: 52-week results from the phase 3 PaTHway Japan trial [0.03%]
日本成人低甲状旁腺素血症患者的palopega特立帕肽治疗:III期PaTHway Japan研究的第52周结果
Kenji Ashida,Masatoshi Nomura,Noriko Makita et al.
Kenji Ashida et al.
PaTHway Japan is an ongoing, phase 3, multicenter, single-arm, open-label trial comprised of a 26-week efficacy period with an extension period through week 182 designed to demonstrate the efficacy, safety, and tolerability of palopegteripa...
Maki Fukami,Kohji Okamura,Shoko Sasaki et al.
Maki Fukami et al.
Males and females show significant differences in body structure, typical behavior, average life expectancy, and disease susceptibility. This review article introduces the current understanding and recent findings on the factors that lead t...
Genetic screening of the insulin-like growth factor 1 receptor gene in children born small for gestational age: the continuing importance of insulin-like growth factor 1 signaling [0.03%]
胰岛素样生长因子1受体基因在宫内发育迟缓儿童中的遗传筛查:胰岛素样生长因子1信号通路的持续重要性
Jun-Hong Park,Yena Lee,Hwal Rim Jeong et al.
Jun-Hong Park et al.
Children born small for gestational age (SGA) who fail to experience catch-up growth often remain short-statured with heterogeneous etiologies, including genetic factors. This study aimed to investigate Insulin-like Growth Factor 1 Receptor...
Association of HLA-DRB1 pocket structures with susceptibility and prognosis of Graves' and Hashimoto's disease [0.03%]
HLA-DRB1袋结构与Graves病和桥本病遗传易感性和预后的关联性研究
Yusuke Noguchi,Yuya Arakawa,Naoya Inoue et al.
Yusuke Noguchi et al.
The physical and/or electrical properties of the peptide-binding pockets of Human Leukocyte Antigen (HLA) class II molecules vary depending on their amino acid sequence, influencing peptide-binding affinity. Previous studies have reported a...
Differences in thyroid hormone prescribing practices between Japan Thyroid Association-certified thyroid specialists and non-certified members: a nationwide survey in Japan [0.03%]
日本甲状腺协会认证的甲状腺专科医生与非认证会员之间甲状腺激素处方习惯差异:一项全国调查研究
Yuji Nagayama,Junichi Tajiri,Tsukasa Murakami et al.
Yuji Nagayama et al.
Thyroid hormone (TH) prescribing practices, particularly on hypothyroid and euthyroid patients, were compared between Japan Thyroid Association (JTA)-certified thyroid specialists and non-certified members. A nationwide questionnaire survey...
Diagnostic criteria for acquired hypothalamic obesity - international expert guidance document [0.03%]
获得性下丘脑肥胖的诊断标准-国际专家指导文件
Hermann L Müller,Tomohiro Tanaka,Tomonobu Hasegawa et al.
Hermann L Müller et al.
Acquired hypothalamic obesity (aHO) presents as rapid, clinically relevant, and persistent weight gain due to hypothalamic damage, and leads to significant morbidity/mortality and decreased quality of life. Causes include craniopharyngioma ...
Comparison of two puncture techniques for fine-needle capillary biopsy in thyroid nodules: a randomized controlled trial [0.03%]
甲状腺结节细针毛细血管活检两种穿刺技术的比较:一项随机对照试验
Pengfei Luo,Wei Ma,Yingguo Jia et al.
Pengfei Luo et al.
To-and-fro puncture and to-and-fro whirling puncture are two common specimen acquisition methods of thyroid fine-needle capillary (FNC) biopsy. While both techniques are widely used, a direct comparison of their outcomes has been lacking. T...
Age-related changes in thyroid hormone profile in pediatric patients with Down syndrome [0.03%]
儿童唐氏综合征患者甲状腺激素谱的年龄相关变化
Machiko Toki,Satoshi Narumi,Junko Hanakawa et al.
Machiko Toki et al.
Children with Down syndrome (DS) have a high prevalence of thyroid dysfunction; however, age-related changes in thyroid hormone profiles remain unclear. We investigated the age-related changes in thyroid function in children with DS. We ret...
Dietary fiber density as an important modifying factor in the association between rice intake and obesity in Japanese type 2 diabetes outpatients: a sex and age-stratified cross-sectional investigation (JDDM 80) [0.03%]
日本2型糖尿病门诊患者中膳食纤维密度为大米摄入和肥胖相关性的重要修饰因子:分性别和年龄的横断面研究(JDDM 80)
Efrem dAvila Ferreira,Mariko Hatta,Laymon Khin et al.
Efrem dAvila Ferreira et al.
A meta-analysis of cohort studies found a positive association between white rice consumption and chronic disease risk, particularly in women. However, the association between rice intake and obesity remains inconsistent across populations....
Efficacy and safety of once-weekly somatrogon following up to 4 years of treatment in Japanese children with growth hormone deficiency: results from an open-label extension of a phase 3 study [0.03%]
一项针对日本生长激素缺乏儿童为期长达4年治疗的一周一次somatrogon疗效和安全性研究:III期临床试验开放标签延长试验结果
Reiko Horikawa,Toshiaki Tanaka,Yukihiro Hasegawa et al.
Reiko Horikawa et al.
Somatrogon is a long-acting recombinant human growth hormone approved in several countries, including Japan, for the treatment of children with growth hormone deficiency (GHD). In this study (Clinicaltrials.gov:NCT03874013) Japanese patient...