Sarcopenia and body temperature-the significance of interorgan metabolic networks in skeletal muscle atrophy [0.03%]
sarcopenia和体温——骨骼肌萎缩的器官间代谢网络的的意义
Yuna Izumi-Mishima,Kazuhiro Nomura,Hiroshi Sakaue
Yuna Izumi-Mishima
The skeletal muscle plays a key role in thermogenesis and energy homeostasis in endotherms. Therefore, reduced skeletal muscle mass and function are closely associated with health disorders such as obesity and hypothermia. In humans, inacti...
Pancreatic α-cell sodium-glucose cotransporter 1 (SGLT1) does not appear to contribute to hyperglucagonemia and glucose intolerance in diabetic mice [0.03%]
在糖尿病小鼠中，胰岛α细胞的钠-葡萄糖共转运蛋白1(SGLT1)似乎不参与高血糖素血症和葡萄糖耐受不良的发展
Yuichi Ikeuchi,Osamu Kikuchi,Masaki Kobayashi et al.
Yuichi Ikeuchi et al.
Pancreatic α-cells secrete glucagon, a hormone that elevates blood glucose levels. In type 2 diabetes, high plasma glucagon levels are associated with hyperglycemia. However, the underlying mechanisms of increasing glucagon secretion remai...
The association between thyroid hormone levels and psychiatric symptoms in patients with mania or depression [0.03%]
甲状腺激素水平与躁狂或抑郁患者精神症状之间的关系
Mariko Hakoshima,Sarina Tanida,Hisayuki Katsuyama et al.
Mariko Hakoshima et al.
Thyroid hormones play a crucial role in regulating mood and cognitive function. However, the effect of thyroid function on psychiatric symptoms remains unclear. In this study, we investigated the association between psychiatric symptoms and...
Clinical practice guidelines for the management of differences of sex development in Japan [0.03%]
日本性别发育差异管理临床实践指南
Tomohiro Ishii,Kenichi Kashimada,Masanobu Kawai et al.
Tomohiro Ishii et al.
Differences of sex development (DSD) are congenital conditions in which chromosomal, gonadal, and anatomical sex characteristics are discordant with typical male or female development. These clinical practice guidelines provide evidence-bas...
Naomi Hizuka
Naomi Hizuka
A correlation analysis between TyG-derived indices and diabetes mellitus: based on the NHANES database [0.03%]
基于NHANES数据库的胰岛素抵抗衍生TyG指数与糖尿病的相关性分析
Xiaohua Yang,Zhuojing Cheng,Ting Sun
Xiaohua Yang
Diabetes mellitus (DM) is a key global public health issue with rising incidence. The triglyceride-glucose (TyG) index has been widely applied to assess insulin resistance and metabolic abnormalities in recent years. However, the relation o...
Impacts of physical, metabolic, and immunological factors on the exophthalmometry values of a contemporary Japanese population with/without Graves' disease [0.03%]
日本当代有/无Graves病人群的突眼度与物理、代谢和免疫学因素的关系
Erika Nakaji,Yuta Nakamura,Ichiro Horie et al.
Erika Nakaji et al.
Proptosis, a key clinical manifestation of thyroid eye disease (TED), serves as an objective indicator of this disease's severity. Although body compositions and the prevalences of myopia and tobacco smoking have changed in Japan, no update...
Long-term effectiveness and safety of daily growth hormone therapy in Japanese children with Noonan syndrome: a post-marketing surveillance study [0.03%]
长期生长激素治疗Noonan综合征日本儿童的有效性和安全性：上市后监测研究
Koji Muroya,Masanobu Kawai,Hiroyuki Yamagishi et al.
Koji Muroya et al.
Reports on long-term safety and effectiveness of daily GH replacement therapy in Japanese children with short stature due to Noonan syndrome (NS) are limited. This post-marketing, prospective, non-interventional study (ClinicalTrials.gov NC...
Congenital adrenal hypoplasia with neurodevelopmental delay due to contiguous Xp21 deletion: a case series with review of literature [0.03%]
Xp21区带连续性缺失导致的先天肾上腺发育不全合并神经发育障碍：一组病例及文献复习
Maki Gau,Ryosei Iemura,Ryuta Orimoto et al.
Maki Gau et al.
X-linked adrenal hypoplasia congenita (AHC) is a rare, life-threatening disorder caused by pathogenic variants in NR0B1 (DAX1), leading to adrenal insufficiency and hypogonadotropic hypogonadism. AHC is often associated with Xp21 contiguous...
Unintentional discontinuation of topical corticosteroids after emergency hospitalization can exacerbate adrenal insufficiency [0.03%]
在急诊住院后意外中断外用皮质类固醇治疗会加重肾上腺功能不全
Hiroya Kitsunai,Yumika Watanabe,Eisuke Nishikawa et al.
Hiroya Kitsunai et al.