Age-dependent discordance in chemiluminescent immunoassay-electrochemiluminescence immunoassay correlation for 25-hydroxyvitamin D measurement reveals methodological considerations for assessment in early infancy [0.03%]
化学发光免疫测定-电化学发光免疫测定法测量25-羟基维生素D的相关性随年龄的变化揭示了评估早期婴儿的方案需考虑的因素
Masashi Ota,Kazushige Ikeda,Kazumi Morisawa et al.
Masashi Ota et al.
Vitamin D (VD) status is assessed by measuring serum 25-hydroxyvitamin D (25(OH)D) levels using immunoassays. In December 2024, a Japanese diagnostic laboratory transitioned from chemiluminescent immunoassay (CLIA: LIAISON® 25 OH Vitamin D...
Adipose-derived stem cell exosomes mitigate ferroptosis and enhance osteogenesis via miR-215-5p-mediated ubiquitin-specific protease 1 suppression [0.03%]
脂肪源性干细胞外泌体通过miR-215-5p介导的泛素特异性蛋白酶1抑制来缓解铁死亡并增强成骨作用
Caihong Sun,Hongwei Wang,Xiulian Lu et al.
Caihong Sun et al.
Osteoporosis (OP) is a metabolic bone disease characterized by impaired bone formation and excessive resorption. Ferroptosis has been implicated in osteoblast dysfunction. Adipose-derived stem cell exosomes (ADSC-exos) have emerged as promi...
Impact of autonomous cortisol secretion on adrenal venous sampling with and without ACTH stimulation in patients with primary aldosteronism [0.03%]
自主性皮质醇分泌对原发性醛固酮增多症患者肾上腺静脉取样的影响（有和无ACTH刺激）
Norio Wada,Arina Miyoshi,Koichi Yamamoto et al.
Norio Wada et al.
The impact of autonomous cortisol secretion (ACS) on adrenal venous sampling (AVS) in patients with primary aldosteronism (PA) remains uncertain. This study aimed to evaluate the effects of ACS on success and lateralization of AVS. From the...
Associations among serum soluble T-cadherin levels, serum adiponectin levels, and metabolic risk factors in a Japanese population undergoing medical health checkups [0.03%]
日本人群医学健康检查中血清可溶性T-钙黏着蛋白与血清脂联素及代谢危险因素之间的关系
Masahito Iioka,Shiro Fukuda,Ryohei Mineo et al.
Masahito Iioka et al.
Soluble T-cadherin (sT-cad), which is a circulating form of membrane T-cadherin, is present in human serum. We examined the relationships among sT-cad levels, adiponectin (APN) levels, and the number of metabolic risk factors in individuals...
Fibroblast growth factor 21-inducing rare sugars prevent diet-induced obesity in male BL/6 mice [0.03%]
诱导稀有糖类预防雄性BL/6小鼠饮食诱导的肥胖症及机制研究
Oulan Ghnb Efendi,Sho Matsui,Daisuke Kohno et al.
Oulan Ghnb Efendi et al.
The consumption of a high-fat, high-sucrose diet (HFHSD) promotes obesity. Although dietary sugars are obesogenic, they activates a negative feedback mechanism between hepatic fibroblast growth factor 21 (FGF21) and oxytocin neurons in the ...
Use, efficacy, and safety of desmopressin for congenital nephrogenic diabetes insipidus in children: a nationwide survey [0.03%]
儿童抗利尿激素治疗先天性肾源性尿崩症的使用、疗效及安全性全国调查
Kento Ikegawa,Masanobu Fujimoto,Kohei Aoyama et al.
Kento Ikegawa et al.
Congenital nephrogenic diabetes insipidus (CNDI) is characterized by resistance of the distal nephrons and collecting ducts to arginine vasopressin (AVP). High doses of 1-deamino-8-D-arginine vasopressin (DDAVP), a V2-receptor-selective ago...
Effects of semaglutide, a GLP-1 receptor agonist, on food preferences in Japanese subjects with type 2 diabetes and visceral fat accumulation [0.03%]
司美格鲁肽对日本2型糖尿病合并向心性肥胖患者饮食偏好的影响研究
Tomoyuki Hara,Yuya Fujishima,Yu Kimura et al.
Tomoyuki Hara et al.
Obesity and type 2 diabetes mellitus (T2DM) are growing global health burdens, with dietary patterns, particularly high intake of carbohydrate- and fat-rich foods, contributing to disease progression. Semaglutide, a glucagon-like peptide-1 ...
Detection rate and maximum diameter of thyroid cysts among children and adolescents in thyroid ultrasound examination, The Fukushima Health Management Survey [0.03%]
福岛健康调查中儿童和青少年甲状腺超声筛查的结节检出率和直径分布特征分析
Mahiro Asano,Chisato Takahashi,Haruka Ejiri et al.
Mahiro Asano et al.
The Fukushima prefectural government is implementing the Thyroid Ultrasound Examination (TUE) program for residents aged 18 years or younger living in Fukushima Prefecture at the time of the nuclear accident. The results of the first-round ...
Consensus on the diagnosis of Cushing's disease: a collaborative statement from the Korean Endocrine Society and Japan Endocrine Society [0.03%]
库欣病诊断共识：来自韩国内分泌学会和日本内分泌学会的合作声明
Jeongmin Lee,Hidenori Fukuoka,Seung Shin Park et al.
Jeongmin Lee et al.
Cushing's disease (CD) is a rare but serious endocrine disorder caused by excessive cortisol secretion due to adrenocorticotropic hormone-secreting pituitary tumors. Despite recent developments in diagnostic criteria and treatment options, ...
Lenvatinib in radioiodine-refractory differentiated thyroid cancer: a real-world institutional analysis [0.03%]
仑伐替尼治疗放射性碘难治性分化型甲状腺癌的疗效分析
Sueyoshi Moritani,Masao Takenobu,Masakazu Yasunaga et al.
Sueyoshi Moritani et al.
Lenvatinib is a standard systemic therapy for radioiodine-refractory differentiated thyroid cancer (RAI-R DTC). Although pivotal trials such as SELECT demonstrated significant efficacy, real-world evidence remains limited, particularly rega...