A predictive nomogram for progression-free survival in radioiodine-refractory papillary thyroid carcinoma after reoperation: a longitudinal study in Vietnam [0.03%]
越南放射性碘难治性甲状腺乳头状癌术后无进展生存预测列线图:一项纵向研究
Nguyen Thi Nhung,Le Ngoc Ha,Van Dong Hoang et al.
Nguyen Thi Nhung et al.
Radioiodine-refractory (RAI-R) papillary thyroid carcinoma (PTC) with disease progression is associated with poor prognosis. This study aimed to develop a predictive nomogram for progression-free survival (PFS) in RAI-R PTC by integrating c...
Machine learning-based prediction of impaired arginine vasopressin secretion during hypertonic saline test [0.03%]
基于机器学习的预测高渗盐水试验期间精氨酸血管加压素分泌受损的效果
Satoshi Naito,Daisuke Hagiwara,Masaki Kitamura et al.
Satoshi Naito et al.
Hypertonic saline infusion and water deprivation tests are commonly used to stimulate arginine vasopressin (AVP) for the diagnosis of AVP deficiency (AVP-D); however, these procedures impose a considerable burden on patients. We aimed to de...
Association of hypothyroidism with adverse pregnancy outcomes: a single-center cohort study in an iodine-sufficient country [0.03%]
原发性甲状腺功能减退症与不良妊娠结局的相关性:碘充足条件下单中心队列研究
Akiko Sankoda,Nagayoshi Umehara,Yusuke Okubo et al.
Akiko Sankoda et al.
Hypothyroidism is reported to associate with adverse pregnancy outcomes. However, there are few reports in iodine-sufficient or -excess areas. We investigated the association of hypothyroidism in early pregnancy with pregnancy outcomes in a...
Long-term survival in MIRAGE syndrome: Insights into systemic manifestations and management with review of literature [0.03%]
MIRAGE综合征的长期生存分析:系统性表现及治疗(附12例文献复习)
Yuki Yamada,Hidehito Kondo,Masashi Nishida et al.
Yuki Yamada et al.
MIRAGE syndrome is a multisystemic disorder with a poor prognosis, caused by gain-of-function mutations in the SAMD9 gene. To date, no comprehensive reports on the systemic manifestations and management of MIRAGE syndrome in adult survivors...
ZFP36-ferroptosis axis as a key renal protective pathway in diabetic kidney disease [0.03%]
ZFP36-铁死亡轴在糖尿病肾脏病中的关键肾保护作用
Anni Li,Yuxuan Ye,Huimin Cao et al.
Anni Li et al.
Diabetic Kidney Disease (DKD) is strongly related to ferroptosis, an iron-dependent form of programmed cell death characterized by the accumulation of lipid peroxides. While ferroptosis is a pivotal mediator in DKD pathogenesis, its upstrea...
Insights from maturity-onset diabetes of the young into impaired insulin secretion in type 2 diabetes [0.03%]
年轻时发病的成熟期糖尿病对2型糖尿病患者胰岛素分泌受损的认识
Yukio Horikawa,Yoshihiro Takahashi,Kazuyoshi Hosomichi
Yukio Horikawa
Monogenic diabetes arises from pathogenic variants in a single gene that are sufficient to cause disease predisposition. In general, a greater functional impact of genetic abnormalities is associated with an earlier age of onset. Accordingl...
Low-affinity IgG-mediated macro-TSH: diagnostic limitations of peak-based gel filtration chromatography-a case report with review of literature [0.03%]
低亲和力的IgG介导的巨TSH:基于峰值的凝胶过滤色谱法诊断的局限性——病例报告及文献综述
Toshihiko Kasahara
Toshihiko Kasahara
Macro-thyroid-stimulating hormone (macro-TSH) is a well-recognized cause of spuriously elevated TSH results. However, its characterization still relies largely on gel filtration chromatography (GFC), which may fail to detect macro-TSH assoc...
Endocrine disorders in pediatric medulloblastoma survivors treated with X-ray or proton beam therapy: a single-institution retrospective study [0.03%]
接受X射线或质子束治疗的儿童髓母细胞瘤幸存者的内分泌紊乱:一项单机构回顾性研究
Naoya Kaneko,Shuntaro Morikawa,Megumi Endo et al.
Naoya Kaneko et al.
Medulloblastoma, a common pediatric central nervous system disease, is managed with surgery, chemotherapy, and craniospinal irradiation (CSI) delivered with either X-rays or protons. Proton-beam CSI, introduced to protect the surrounding ti...
Early predictors of 6-month thyroid-stimulating antibody levels after radioactive iodine therapy for Graves' disease: implications for pregnancy planning [0.03%]
放射性碘治疗Graves病后6个月促甲状腺激素受体抗体水平的早期预测因素及其对妊娠规划的意义
Seigo Tachibana,Yuji Nagayama,Takashi Fukuda et al.
Seigo Tachibana et al.
Current guidelines recommend a 6-month contraception period following radioactive iodine therapy (RAIT) for Graves' disease (GD), based primarily on radiation safety considerations; however, they do not account for the post-treatment surge ...
Multiple thyroid cysts: a benign and stable clinical entity based on longitudinal data [0.03%]
基于纵向数据的多发甲状腺囊肿:一种良性且稳定的临床实体
Yuji Nagayama,Seigo Tachibana,Takashi Fukuda et al.
Yuji Nagayama et al.
Multiple thyroid cysts are commonly detected by ultrasonography, and are considered clinically insignificant. On the other hand, polycystic thyroid disease (PCTD) has been proposed as a cause of antibody-negative hypothyroidism in iodine-re...