Acanthosis nigricans as a diagnostic clue for familial partial lipodystrophy type 2: a case report with review of literature on Japanese cases [0.03%]
棘皮病可作为诊断家族性部分脂odystrophy类型2的线索：带有日本病例文献回顾的病例报告
Takuya Kitamura,Toru Kusakabe,Yuki Ishihara et al.
Takuya Kitamura et al.
Familial partial lipodystrophy (FPLD) is a rare inherited disorder characterized by limb adipose tissue atrophy and metabolic abnormalities, including severe insulin resistance. However, diagnosis is often delayed because the characteristic...
Overlap syndrome between sarcoidosis and Sjögren's disease presenting as hypopituitarism: case report and review of literature [0.03%]
与Sjogren病重叠的肺泡出血型狼疮样肉芽肿病伴垂体功能减退症一例及文献复习
Yuichiro Iwamoto,Noriko Yoshimura,Ayaka Harada et al.
Yuichiro Iwamoto et al.
Sarcoidosis is a granulomatous disease that affects multiple organs; however, pituitary involvement is extremely rare. Although autoimmune diseases, such as Sjögren's disease (SjD), may coexist, overlapping cases presenting with hypopituit...
Soluble tumor necrosis factor receptors in diabetes: risk sensing and receptor-resolved targeting [0.03%]
可溶性肿瘤坏死因子受体与糖尿病：风险感应和受体解析靶向治疗
Qi Zhu,Yu Liu,Chen Yang et al.
Qi Zhu et al.
Diabetes drives a major burden of kidney failure, cardiovascular disease, and premature mortality, yet current clinical markers incompletely capture individual trajectories of organ decline. Soluble tumor necrosis factor receptors 1 and 2 (...
A predictive nomogram for progression-free survival in radioiodine-refractory papillary thyroid carcinoma after reoperation: a longitudinal study in Vietnam [0.03%]
越南放射性碘难治性甲状腺乳头状癌术后无进展生存预测列线图：一项纵向研究
Nguyen Thi Nhung,Le Ngoc Ha,Van Dong Hoang et al.
Nguyen Thi Nhung et al.
Radioiodine-refractory (RAI-R) papillary thyroid carcinoma (PTC) with disease progression is associated with poor prognosis. This study aimed to develop a predictive nomogram for progression-free survival (PFS) in RAI-R PTC by integrating c...
Machine learning-based prediction of impaired arginine vasopressin secretion during hypertonic saline test [0.03%]
基于机器学习的预测高渗盐水试验期间精氨酸血管加压素分泌受损的效果
Satoshi Naito,Daisuke Hagiwara,Masaki Kitamura et al.
Satoshi Naito et al.
Hypertonic saline infusion and water deprivation tests are commonly used to stimulate arginine vasopressin (AVP) for the diagnosis of AVP deficiency (AVP-D); however, these procedures impose a considerable burden on patients. We aimed to de...
Association of hypothyroidism with adverse pregnancy outcomes: a single-center cohort study in an iodine-sufficient country [0.03%]
原发性甲状腺功能减退症与不良妊娠结局的相关性：碘充足条件下单中心队列研究
Akiko Sankoda,Nagayoshi Umehara,Yusuke Okubo et al.
Akiko Sankoda et al.
Hypothyroidism is reported to associate with adverse pregnancy outcomes. However, there are few reports in iodine-sufficient or -excess areas. We investigated the association of hypothyroidism in early pregnancy with pregnancy outcomes in a...
Long-term survival in MIRAGE syndrome: Insights into systemic manifestations and management with review of literature [0.03%]
MIRAGE综合征的长期生存分析：系统性表现及治疗（附12例文献复习）
Yuki Yamada,Hidehito Kondo,Masashi Nishida et al.
Yuki Yamada et al.
MIRAGE syndrome is a multisystemic disorder with a poor prognosis, caused by gain-of-function mutations in the SAMD9 gene. To date, no comprehensive reports on the systemic manifestations and management of MIRAGE syndrome in adult survivors...
ZFP36-ferroptosis axis as a key renal protective pathway in diabetic kidney disease [0.03%]
ZFP36-铁死亡轴在糖尿病肾脏病中的关键肾保护作用
Anni Li,Yuxuan Ye,Huimin Cao et al.
Anni Li et al.
Diabetic Kidney Disease (DKD) is strongly related to ferroptosis, an iron-dependent form of programmed cell death characterized by the accumulation of lipid peroxides. While ferroptosis is a pivotal mediator in DKD pathogenesis, its upstrea...
Insights from maturity-onset diabetes of the young into impaired insulin secretion in type 2 diabetes [0.03%]
年轻时发病的成熟期糖尿病对2型糖尿病患者胰岛素分泌受损的认识
Yukio Horikawa,Yoshihiro Takahashi,Kazuyoshi Hosomichi
Yukio Horikawa
Monogenic diabetes arises from pathogenic variants in a single gene that are sufficient to cause disease predisposition. In general, a greater functional impact of genetic abnormalities is associated with an earlier age of onset. Accordingl...
Low-affinity IgG-mediated macro-TSH: diagnostic limitations of peak-based gel filtration chromatography-a case report with review of literature [0.03%]
低亲和力的IgG介导的巨TSH：基于峰值的凝胶过滤色谱法诊断的局限性——病例报告及文献综述
Toshihiko Kasahara
Toshihiko Kasahara
Macro-thyroid-stimulating hormone (macro-TSH) is a well-recognized cause of spuriously elevated TSH results. However, its characterization still relies largely on gel filtration chromatography (GFC), which may fail to detect macro-TSH assoc...