Differentiating TRAb-positive painless thyroiditis from Graves' disease using biochemical and ultrasound findings [0.03%]
利用生化和超声检查结果区分无痛性甲状腺炎伴TRAb阳性与Graves病
Yoshiki Furumura,Mitsuru Ito,Itaru Monno et al.
Yoshiki Furumura et al.
Differentiating painless thyroiditis (PT) from Graves' disease (GD) is important for appropriate management. This study evaluated whether thyroid-stimulating hormone (TSH) receptor antibody (TRAb)-positive PT can be differentiated from GD u...
Indicators for predicting continuous insulin infusion therapy-related hypokalemia: multicenter retrospective cohort study [0.03%]
预测连续胰岛素输注相关低钾血症的指标：多中心回顾性队列研究
Yuichiro Iwamoto,Tomohiko Kimura,Masato Kubo et al.
Yuichiro Iwamoto et al.
Hypokalemia is a common and potentially life-threatening complication of continuous intravenous insulin infusion (CII) in patients with hyperglycemic crises. However, no simple quantitative indicator can estimate the risk of hypokalemia at ...
From cross-section to prognosis: risk factors for renal function deterioration in primary hyperparathyroidism [0.03%]
从横断面到预后：原发性甲状旁腺功能亢进症肾功能恶化的影响因素分析
Takuma Yamoto,Masakazu Notsu,Keizo Kanasaki
Takuma Yamoto
Renal dysfunction is an important complication of primary hyperparathyroidism (pHPT). However, the factors associated with a decline in estimated glomerular filtration rate (eGFR) in patients with pHPT have not been fully investigated. This...
γ-Secretase inhibitor ameliorates thyroid autoimmune damage via blocking Notch1 signaling and reducing γδT17 cells in EAT mice [0.03%]
通过抑制Notch1信号通路和减少γδT17细胞改善甲状腺自身免疫损伤的γ-分泌酶抑制剂的研究(EIF临床前研究)
Jue Wang,Longfei Ding,Chengyan He et al.
Jue Wang et al.
In order to explore if γ-secretase inhibitor can regulate γδT17 cells by blockading Notch1 signaling pathway and then affect thyroid autoimmune damage in experimental autoimmune thyroiditis (EAT) mice. Twenty-four female C57BL/6 mice, 6 ...
Efficacy and safety of dabrafenib plus trametinib in BRAFV600E-mutated advanced thyroid carcinoma: Real world experience in 37 patients [0.03%]
达拉菲尼联合曲美替尼治疗BRAF V600E突变型甲状腺癌患者的有效性和安全性：37例患者的现实世界经验
Haruhiko Yamazaki,Nobuyasu Suganuma,Mei Kadoya et al.
Haruhiko Yamazaki et al.
This study aimed to investigate the clinical efficacy and safety of dabrafenib plus trametinib for BRAFV600E-mutated advanced thyroid carcinoma in a Japanese real-world setting. We analyzed 37 BRAFV600E-mutated advanced thyroid carcinoma pa...
Efficacy of iodine-131-metaiodobenzylguanidine therapy for multiple endocrine neoplasia type 2A-associated metastatic pheochromocytoma: case report and literature review [0.03%]
碘131-MIBG治疗多发性内分泌腺瘤病ⅡA型伴发转移性嗜铬细胞瘤的疗效观察：病例报告及文献复习
Kentaro Suda,Noriko Kimura,Toshihiro Maeda et al.
Kentaro Suda et al.
Malignant transformation in multiple endocrine neoplasia type 2 (MEN2)-associated pheochromocytoma is rare, and there have been few reports of treatment with 131I-metaiodobenzylguanidine (MIBG) therapy. Here, we describe a 47-year-old woman...
Anti-pituitary-specific transcription factor-1 hypophysitis developing after thymoma resection: a case report with review of literature [0.03%]
垂体特异性转录因子-1垂体炎继发于胸腺瘤切除术后一例报告及文献复习
Hitomi Konishi,Yui Yamashita,Yuma Motomura et al.
Hitomi Konishi et al.
Anti-pituitary-specific transcription factor-1 (PIT-1) hypophysitis is an acquired autoimmune disorder characterized by selective deficiencies of growth hormone (GH), prolactin (PRL), and thyrotropin (TSH). It is typically driven by ectopic...
Acanthosis nigricans as a diagnostic clue for familial partial lipodystrophy type 2: a case report with review of literature on Japanese cases [0.03%]
棘皮病可作为诊断家族性部分脂odystrophy类型2的线索：带有日本病例文献回顾的病例报告
Takuya Kitamura,Toru Kusakabe,Yuki Ishihara et al.
Takuya Kitamura et al.
Familial partial lipodystrophy (FPLD) is a rare inherited disorder characterized by limb adipose tissue atrophy and metabolic abnormalities, including severe insulin resistance. However, diagnosis is often delayed because the characteristic...
Overlap syndrome between sarcoidosis and Sjögren's disease presenting as hypopituitarism: case report and review of literature [0.03%]
与Sjogren病重叠的肺泡出血型狼疮样肉芽肿病伴垂体功能减退症一例及文献复习
Yuichiro Iwamoto,Noriko Yoshimura,Ayaka Harada et al.
Yuichiro Iwamoto et al.
Sarcoidosis is a granulomatous disease that affects multiple organs; however, pituitary involvement is extremely rare. Although autoimmune diseases, such as Sjögren's disease (SjD), may coexist, overlapping cases presenting with hypopituit...
Soluble tumor necrosis factor receptors in diabetes: risk sensing and receptor-resolved targeting [0.03%]
可溶性肿瘤坏死因子受体与糖尿病：风险感应和受体解析靶向治疗
Qi Zhu,Yu Liu,Chen Yang et al.
Qi Zhu et al.
Diabetes drives a major burden of kidney failure, cardiovascular disease, and premature mortality, yet current clinical markers incompletely capture individual trajectories of organ decline. Soluble tumor necrosis factor receptors 1 and 2 (...