Early diagnosis of capivasertib-associated severe hyperglycemia with diabetic ketosis diagnosed in routine clinical practice: a case report with review of literature [0.03%]
卡博维司特相关重度高血糖及糖尿病酮症的早期诊断——一例常规临床实践中的个案报告及文献回顾
Masashi Yoshikawa,Keiichiro Takahashi,Satoshi Yoshino et al.
Masashi Yoshikawa et al.
Capivasertib, an oral pan-AKT inhibitor, is a therapeutic option for hormone receptor-positive advanced breast cancer. While hyperglycemia is a recognized adverse effect of AKT inhibition, its diagnosis is often delayed in routine clinical ...
Mari Yamamoto,Yuri Mukoyama,Kentaro Kishi et al.
Mari Yamamoto et al.
Cushing's disease (CD) is very rare in children. Nineteen children (≤18 years) with CD (median age at diagnosis: 13 [6-17] years; 12 females) were retrospectively analyzed using medical records (1994-2025) from Toranomon Hospital, Tokyo, J...
Associations of stress hormones, autonomic function, and endothelial function in patients with diabetes [0.03%]
糖尿病患者的应激激素、自主神经功能和内皮细胞功能之间的关系
Takanobu Saheki,Keisuke Takahashi,Eri Harada et al.
Takanobu Saheki et al.
Endothelial dysfunction is an early feature of diabetic vascular injury. Stress-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis, together with autonomic imbalance, may contribute to endothelial dysfunction. However, its ...
Inter- and intratumoral heterogeneity of aldosterone-producing adenomas: recent advances and clinical implications [0.03%]
醛固酮分泌腺瘤的异质性：近期研究进展及临床意义
Masanori Murakami
Masanori Murakami
Primary aldosteronism is the most common form of secondary hypertension, and aldosterone-producing adenoma (APA) is the most prevalent surgically curable subtype of primary aldosteronism. Over the past decade, the identification of recurren...
Metachronous multiple insulinomas in oculo-facio-cardio-dental syndrome harboring a novel BCOR deletion: a case report with review of literature [0.03%]
眼脸心牙征候群伴新颖的BCOR基因缺失继发多发异时性胰岛细胞瘤一例及文献复习
Shinsuke Noso,Hiroki Miki,Yoshihisa Hiromine et al.
Shinsuke Noso et al.
Oculo-facio-cardio-dental (OFCD) syndrome is a rare X-linked dominant disorder caused by pathogenic variants in the BCOR gene and is characterized by distinctive craniofacial, ocular, cardiac, and dental abnormalities. Although OFCD syndrom...
Establishment of a prognostic score for distant recurrence in follicular thyroid carcinoma [0.03%]
一种预测滤泡甲状腺癌远处转移的预后评分系统
Yasuhiro Ito,Masashi Yamamoto,Mitsuyoshi Hirokawa et al.
Yasuhiro Ito et al.
Follicular thyroid carcinoma (FTC) is known to occasionally show distant recurrence (DR); however, no prognostic scoring system has been established. Furthermore, although prognostic factors have been identified, their weights as predictors...
Recurrent Cushing's disease due to postoperative seeding of tumor cells in the sphenoid sinus: a case report with review of the literature [0.03%]
术后蝶窦肿瘤细胞种植引起的库欣病复发：病例报告及文献复习
Tatsuma Matsuda,Noriaki Fukuhara,Masahiko Tosaka et al.
Tatsuma Matsuda et al.
Recurrent Cushing's disease is most commonly caused by residual or newly developed pituitary neuroendocrine tumor (PitNET) tissue within the sellar region. Extrasellar recurrence due to postoperative tumor cell seeding is exceedingly rare. ...
The clinical significance of SIGLEC1 mRNA levels derived from peripheral leukocytes in autoimmune thyroid diseases and type 1 diabetes [0.03%]
自身免疫性甲状腺疾病和1型糖尿病外周白细胞衍生的SIGLEC1 mRNA水平的临床意义
Mami Gamo-Kawasaki,Shiori Kawai,Ayano Takei et al.
Mami Gamo-Kawasaki et al.
Autoimmune thyroid diseases (AITD), including Graves' disease (GD) and Hashimoto's thyroiditis (HT), may coexist with Type 1 diabetes mellitus (T1DM) as autoimmune polyglandular syndrome type 3 (APS3). Sialic acid-binding immunoglobulin-lik...
Intracrine androgen metabolism in the meibomian gland: regulation, circadian control, and implications in dry eye disease [0.03%]
眼睑板腺内的类固醇内分泌代谢：调控、昼夜节律及干眼病发病机制中的作用
Takahito Miyake,Masao Doi
Takahito Miyake
The meibomian glands play a central role in maintaining ocular surface homeostasis by producing meibum, which is the lipid layer of the tear film that suppresses tear evaporation. Dysregulation of the secretion of this lipid leads to meibom...
Effect of social jetlag on metabolic syndrome varies by body mass index: evidence from Taiwan Biobank [0.03%]
社交时差对代谢综合征的影响因体质指数而异：来自台湾生物样本库的证据
Shih-Kai Kao,Kai-Hsuan Cheng,Jerry Cheng-Yen Lai et al.
Shih-Kai Kao et al.
Social jetlag (SJL), the misalignment between biological and social time, has been linked to adverse metabolic outcomes. However, the effect of body mass index (BMI) on this association remains unclear, particularly in Asian populations. Th...