Inter- and intratumoral heterogeneity of aldosterone-producing adenomas: recent advances and clinical implications [0.03%]
醛固酮分泌腺瘤的异质性：近期研究进展及临床意义
Masanori Murakami
Masanori Murakami
Primary aldosteronism is the most common form of secondary hypertension, and aldosterone-producing adenoma (APA) is the most prevalent surgically curable subtype of primary aldosteronism. Over the past decade, the identification of recurren...
Metachronous multiple insulinomas in oculo-facio-cardio-dental syndrome harboring a novel BCOR deletion: a case report with review of literature [0.03%]
眼脸心牙征候群伴新颖的BCOR基因缺失继发多发异时性胰岛细胞瘤一例及文献复习
Shinsuke Noso,Hiroki Miki,Yoshihisa Hiromine et al.
Shinsuke Noso et al.
Oculo-facio-cardio-dental (OFCD) syndrome is a rare X-linked dominant disorder caused by pathogenic variants in the BCOR gene and is characterized by distinctive craniofacial, ocular, cardiac, and dental abnormalities. Although OFCD syndrom...
Establishment of a prognostic score for distant recurrence in follicular thyroid carcinoma [0.03%]
一种预测滤泡甲状腺癌远处转移的预后评分系统
Yasuhiro Ito,Masashi Yamamoto,Mitsuyoshi Hirokawa et al.
Yasuhiro Ito et al.
Follicular thyroid carcinoma (FTC) is known to occasionally show distant recurrence (DR); however, no prognostic scoring system has been established. Furthermore, although prognostic factors have been identified, their weights as predictors...
Recurrent Cushing's disease due to postoperative seeding of tumor cells in the sphenoid sinus: a case report with review of the literature [0.03%]
术后蝶窦肿瘤细胞种植引起的库欣病复发：病例报告及文献复习
Tatsuma Matsuda,Noriaki Fukuhara,Masahiko Tosaka et al.
Tatsuma Matsuda et al.
Recurrent Cushing's disease is most commonly caused by residual or newly developed pituitary neuroendocrine tumor (PitNET) tissue within the sellar region. Extrasellar recurrence due to postoperative tumor cell seeding is exceedingly rare. ...
The clinical significance of SIGLEC1 mRNA levels derived from peripheral leukocytes in autoimmune thyroid diseases and type 1 diabetes [0.03%]
自身免疫性甲状腺疾病和1型糖尿病外周白细胞衍生的SIGLEC1 mRNA水平的临床意义
Mami Gamo-Kawasaki,Shiori Kawai,Ayano Takei et al.
Mami Gamo-Kawasaki et al.
Autoimmune thyroid diseases (AITD), including Graves' disease (GD) and Hashimoto's thyroiditis (HT), may coexist with Type 1 diabetes mellitus (T1DM) as autoimmune polyglandular syndrome type 3 (APS3). Sialic acid-binding immunoglobulin-lik...
Intracrine androgen metabolism in the meibomian gland: regulation, circadian control, and implications in dry eye disease [0.03%]
眼睑板腺内的类固醇内分泌代谢：调控、昼夜节律及干眼病发病机制中的作用
Takahito Miyake,Masao Doi
Takahito Miyake
The meibomian glands play a central role in maintaining ocular surface homeostasis by producing meibum, which is the lipid layer of the tear film that suppresses tear evaporation. Dysregulation of the secretion of this lipid leads to meibom...
Effect of social jetlag on metabolic syndrome varies by body mass index: evidence from Taiwan Biobank [0.03%]
社交时差对代谢综合征的影响因体质指数而异：来自台湾生物样本库的证据
Shih-Kai Kao,Kai-Hsuan Cheng,Jerry Cheng-Yen Lai et al.
Shih-Kai Kao et al.
Social jetlag (SJL), the misalignment between biological and social time, has been linked to adverse metabolic outcomes. However, the effect of body mass index (BMI) on this association remains unclear, particularly in Asian populations. Th...
Hiroaki Masuzaki,Izumi Fukuda,Tadahiro Kitamura et al.
Hiroaki Masuzaki et al.
Multimodal management of giant prolactinoma with extensive amyloid spherule deposition: a case report with review of the literature [0.03%]
巨大泌乳素瘤伴广泛类黏液体沉积的多模式治疗：病例报告及文献复习
Aysel Unver Ozkahraman,Merve Korkmaz Yilmaz,Huseyin Karatay et al.
Aysel Unver Ozkahraman et al.
Amyloid spherule-containing prolactinomas are rare entities associated with dopamine agonist (DA) resistance and aggressive behaviour. We report a giant amyloid spherule-containing prolactinoma with a substantial tumour burden and markedly ...
Nilufer Ozdemir,Seda Sabah Ozcan,Ayse Ece Turkmen et al.
Nilufer Ozdemir et al.
Telomeres maintain genomic integrity during cell replication by preventing chromosomal fusions. Beside genetic influences, telomere length is affected by environmental factors such as oxidative stress and inflammation. These mechanisms also...