Drug-induced hyperglycemia in the Japanese Adverse Drug Event Report database: association of evelolimus use with diabetes [0.03%]
日本药品不良事件报告数据库中的药物诱发性高血糖与依维莫司使用相关的糖尿病
Hiromi Konishi,Jun Shirakawa,Masanori Arai et al.
Hiromi Konishi et al.
Some categories of drugs are known for causing hyperglycemia or diabetes such as steroids, antipsychotics, and immunosuppressant. However, there has been little evidence from studies about the proportion of each drug in the context of drug-...
Comparison of therapeutic effects of acarbose and metformin under different β-cell function status in Chinese patients with type 2 diabetes [0.03%]
不同β细胞功能状态下阿卡波糖与二甲双胍治疗2型糖尿病疗效比较研究
Jing Fu,Jia Liu,Yuan Xu et al.
Jing Fu et al.
MARCH study suggested that acarbose had similar therapeutic effect on glycated hemoglobin reduction compared to metformin in newly diagnosed type 2 diabetes patients as initial therapy in China. We aimed to investigate whether the efficacy ...
Randomized Controlled Trial
Endocrine journal. 2019 May 28;66(5):443-450. DOI:10.1507/endocrj.EJ18-0466 2019
Falsely elevated plasma ACTH levels measured by the Elecsys assay related to heterophilic antibody in a case of secondary adrenocortical insufficiency [0.03%]
异磷脂抗体导致的二次肾上腺皮质功能减退患者血浆ACTH水平假性升高1例报告
Koji Morita,Masumi Ogawa,Michiko Kimura et al.
Koji Morita et al.
A 49-year-old woman with membranous nephropathy was referred to our hospital during the tapering of oral prednisolone, because of suspicion of primary adrenal insufficiency based on a plasma ACTH level of 399.1 pg/mL in the Elecsys assay an...
Tezcan Sezgin,Muhammet İrfan Dönmez,Aylin Dirican et al.
Tezcan Sezgin et al.
Partial androgen insensitivity syndrome (PAIS) is a form of disorders of sexual development. Besides the issues of gender assignment, the fate of gonads in these patients poses a challenging problem. Debate still remains on the need and/or ...
Molecular analysis and literature-based hypothesis of an immunonegative prostate small cell carcinoma causing ectopic ACTH syndrome [0.03%]
分子分析及基于文献的假说：一种免疫阴性的前列腺小细胞癌引发异位ACTH综合征
Maki Takeuchi,Junichiro Sato,Katsunori Manaka et al.
Maki Takeuchi et al.
Ectopic ACTH syndrome (EAS) due to a prostate small cell carcinoma (SCC) is very rare with only 26 cases reported to date and has a poor prognosis. We here describe another case of this disorder that was clinically typical based on prior re...
The long-term follow-up of patients with thionamide-treated Graves' hyperthyroidism [0.03%]
硫脲类药物治疗的Graves病甲亢患者的长期随访研究
Sachiko Bandai,Ken Okamura,Megumi Fujikawa et al.
Sachiko Bandai et al.
Since there have been few reports on the long-term prognosis of Graves' hyperthyroidism, the prognosis of 549 Graves' hyperthyroidism patients initially treated with thionamide and followed for >8 (range: 8.6-36.4) years was studied, evalua...
Circulating zinc-α2-glycoprotein is reduced in women with polycystic ovary syndrome, but can be increased by exenatide or metformin treatment [0.03%]
环锌-α2-甘露糖蛋白在多囊卵巢综合征女性中降低，但可以通过艾塞那肽或二甲双胍治疗而升高
Siyuan Zheng,En Liu,Ying Zhang et al.
Siyuan Zheng et al.
The study was to investigate circulating zinc-α2-glycoprotein (ZAG) concentrations in women with PCOS, and changes in ZAG levels after exenatide or metformin treatment. One hundred eighty-two women with polycystic ovary syndrome (PCOS) who...
Randomized Controlled Trial
Endocrine journal. 2019 Jun 28;66(6):555-562. DOI:10.1507/endocrj.EJ18-0153 2019
Urinary iodine is increased in papillary thyroid carcinoma but is not altered by regional population iodine intake status: a meta-analysis and implications [0.03%]
尿碘与乳头状甲状腺癌关系的meta分析及意义：未受区域人口碘营养状况的影响
Ann-Rong Yan,Xiaojuan Zhang,Hong Shen et al.
Ann-Rong Yan et al.
Excessive iodine intake has been associated with increased risk of thyroid cancer (TC) in many studies, but the results have not been consistent. Since it was common knowledge that urinary iodine (UI) is considered a sensitive marker of cur...
Meta-Analysis
Endocrine journal. 2019 Jun 28;66(6):497-514. DOI:10.1507/endocrj.EJ18-0532 2019
Reducing the gender gap in academic activities: a 10-year progress report by the Japan Endocrine Society Women Endocrinologists Association (JES-We-Can) [0.03%]
日本内分泌学会女性内分泌学家协会(JES-We-Can)关于学术活动中性别差距的十年进展报告
Miyuki Katai,Kanako Sakurai,Megumi Fujita et al.
Miyuki Katai et al.
The Japan Endocrine Society (JES) has the largest ratio of female membership among societies associated with Internal Medicine in Japan; half of female members are in their 20s or 30s at present. In 2009, JES organized the "JES-We-Can" comm...
Lapatinib decreases the ACTH production and proliferation of corticotroph tumor cells [0.03%]
拉帕替尼减少促肾上腺皮质激素的产生和促肾上腺皮质肿瘤细胞的增殖
Yuko Asari,Kazunori Kageyama,Aya Sugiyama et al.
Yuko Asari et al.
Cushing's disease is almost always caused by hypersecretion of adrenocorticotropic hormone (ACTH) from a pituitary adenoma. A mutation in the deubiquitinase gene USP8 has been found in human ACTH-producing pituitary adenoma cells. This muta...