Enhanced synthesis of antibody-functionalized gold nanoparticles for multiplexed exosome detection via mass signal amplification in LDI-TOF MS [0.03%]
通过LDI-TOF MS中的质量信号放大进行多重外泌体检测的抗体功能化金纳米粒子的增强合成
Gaon Jo,Woon-Seok Yeo
Gaon Jo
We present a novel method for sensitive exosomal protein detection using organic matrix-free laser desorption/ionization time-of-flight mass spectrometry (LDI-TOF MS) and gold nanoparticles (AuNPs) functionalized with mass tags for signal a...
A high-throughput sequence determination for one cyclic peptide immobilized on a single bead by the one-pot cyanidation followed by MALDI-TOF-MS/MS for discovery of interacting peptides [0.03%]
一种高通量测定固定在单珠上的一个环形肽的方法：通过一步氰化后结合基质辅助激光解吸飞行时间串联质谱法发现相互作用的多肽
Takeshi Kasama,Kiyoshi Nokihara
Takeshi Kasama
One cyclic peptide immobilized on one gel-type bead has been employed for the discovery of both interacting peptides and/or medicinal medium-sized molecules. Although high-throughput characterization of recognized peptides has been a bottle...
Optical lateral flow assays in early diagnosis of SARS-CoV-2 infection [0.03%]
SARS-CoV-2感染早期诊断的光学侧向流动测定法
Rushi Liang,Aiping Fan,Feiqian Wang et al.
Rushi Liang et al.
So far, the 2019 novel coronavirus (COVID-19) is spreading widely worldwide. The early diagnosis of infection by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is essential to provide timely treatment and prevent its furth...
Application of on-line sample preconcentration by large-volume dual preconcentration by isotachophoresis and stacking (LDIS) on straight-channel microchips [0.03%]
大体积同向流动电泳-装样富集法在线样品预处理及其在直线微芯片上的应用研究
Fumihiko Kitagawa,Kazuki Takahashi,Reina Osanai et al.
Fumihiko Kitagawa et al.
In this study, large-volume dual preconcentration by isotachophoresis and stacking (LDIS) which is an on-line sample preconcentration technique coupling large-volume sample stacking with an electroosmotic flow pump (LVSEP) with transient is...
Comprehensive extraction study using N,N-dioctylthiodiglycolamic acid: effect of S donor on metal extraction [0.03%]
S供体对金属萃取影响的全面研究：N，N-辛基硫代二甘醇酸的萃取行为研究
Kojiro Shimojo,Iori Fujiwara,Takumi Saito et al.
Kojiro Shimojo et al.
Extraction ability of N,N-dioctylthiodiglycolamic acid (T-DODGAA), a soft-base sulfur donor ligand with an amide group and a carboxylic acid connected by a thioether chain, for 56 metal ions have been comprehensively investigated and compar...
In vitro evaluation of novel SN-38 prodrug activated by α-rhamnosidase of exogenous enzyme [0.03%]
体外评价一种新的伊立替康前药及其利用外源酶α-L岩藻糖苷酶的激活实验
Teruki Nii,Shoichi Hijii,Ryosuke Kaneko et al.
Teruki Nii et al.
This study introduces the α-rhamnose (Rham)-conjugated prodrug of SN-38 (Rham-SN-38) as a promising alternative to irinotecan. α-rhamnosidase, responsible for SN-38 release from Rham-SN-38, does not express in human cells, minimizing indi...
Revolutionizing scandium detection in real samples: Unleashing the power of sol-gel-based optical sensor [0.03%]
变革性钪检测方法在真实样品中的应用——基于溶胶-凝胶光学传感器的强大功能解锁
Salah M El-Bahy,Abdullah A A Sari,Alaa S Amin et al.
Salah M El-Bahy et al.
The development of a highly selective and ultra-sensitive optical sensor for detecting scandium (Sc3+) ions involves incorporating the reagent 2,3-dichloro-6-(3-carboxy-2-hydroxy-1-naphthylazo)quinoxaline (DCHNAQ) into a silica sol-gel thin...
Thiol-based chemically modified carbon screen-printed electrode for simultaneous quantification of trace level Pb(II) and Cd(II) [0.03%]
一种巯基化学修饰的碳印刷电极同时检测痕量Pb(II)和Cd(II)的新方法研究
Mritunjay S Tiwari,Arun K Kadu
Mritunjay S Tiwari
Present work reports, the development of a novel electrochemical sensor based on a diazonium-coupling reaction and covalent attachment of the -NH2 group of cysteamine (Cyst) on screen-printed carbon electrode (SPCE), for simultaneous determ...
Highly sensitive and novel dual-emission fluorescence nanosensor utilizing hybrid carbon dots-quantum dots for ratiometric determination of chlorpromazine [0.03%]
一种新型比率检测氯丙嗪的双发射荧光纳米传感器（碳点-量子点杂化材料）
Saeedeh Narimani,Naser Samadi,Elnaz Delnavaz
Saeedeh Narimani
Herein, a ratiometric fluorimetric nanosensor is introduced for the sensitive and selective analysis of chlorpromazine (CPZ) via employing blue-emitting B-doped carbon dots (B-CDs) as the reference fluorophore and green-emitting CdTe capped...
Anodized CuO-based reusable non-enzymatic glucose sensor as an alternative method for the analysis of pharmaceutical glucose infusions: a cyclic voltammetric approach [0.03%]
一种用于制药葡萄糖输液分析的替代方法：作为可重复使用的非酶型葡萄糖传感器的阳极CuO及其循环伏安法研究
Suhan P Panditharatne,D Yureka Imali,E Chavin J Perera et al.
Suhan P Panditharatne et al.
Analyzing pharmaceutical products is a quality control requirement in a production facility. This study presents a CuO electrode-based reusable non-enzymatic sensor as an alternative method for rapid analysis of glucose levels in glucose in...