Characterization of the Cattle TCR β CDR3 Repertoire and Gene Rearrangement Bias Influenced by Recombination Signal Sequences and Physical Distance [0.03%]
受重组信号序列和物理距离影响的牛TCRβ CDR3库表征及其基因重排偏向性
Fengli Wu,Yunlan Deng,Yuanyuan Xu et al.
Fengli Wu et al.
Cattle exhibit distinct immune system features, including ultra-long IGH CDR3 regions, which are characteristic of their adaptive immunity. However, less is known about the diversity and functional aspects of their T cell receptor (TCR) β ...
Bordetella BcrH1 and BcrH2 Are Specific Chaperones for the Pore-Forming Complex [0.03%]
百日咳博德特氏菌菌毛素BcrH1和BcrH2是毒力因子复合物的分子伴侣蛋白质
Yuya Kishino,Toshinobu Ogawa,Hiroko Sato et al.
Yuya Kishino et al.
Bordetella has a type III secretion system that secretes virulence proteins crucial to the establishment of infection. The genes encoding components of the Bordetella type III secretion system are located in the bsc region on the chromosome...
Distinct 5' UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses [0.03%]
禽类正纤细病毒X/P双顺反子mRNA的5'-UTR在翻译需求上的差异性要求
Meng-Chi Wu,Takehiro Kanda,Ryo Komorizono et al.
Meng-Chi Wu et al.
Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5' untranslated region (5' UTR) of the X/P mRNA controls the translatio...
Tofazzal Md Rakib,Lipi Akter,Hiroshi Shimoda et al.
Tofazzal Md Rakib et al.
Oz virus (OZV) is a tick-borne, six-segmented, negative-strand RNA virus in the genus Thogotovirus, family Orthomyxoviridae. A fatal human infection was reported in Japan in 2023. In this study, we established a reverse genetics system to g...
Hydroxypropyl Cellulose Enhances Immune Responses to the Current Seasonal Influenza Vaccine in Mice [0.03%]
羟丙基纤维素可增强小鼠对当前季节性流感疫苗的免疫反应
Nantaporn Kaewaroon,Sara Yoshimoto,Luthfi Muawan et al.
Nantaporn Kaewaroon et al.
Influenza A and B viruses cause annual epidemics and continue to pose global public health concerns. The most effective approach to preventing or mitigating the severity of influenza is vaccination. Inactivated split influenza HA vaccines a...
Immunostimulatory Activity of Solubilized Peptidoglycan Derivatives Prepared From Lactic Acid Bacteria [0.03%]
乳酸菌多糖的免疫刺激活性研究
Sho Noguchi,Momoko Nakayama,Masahiro Eguchi et al.
Sho Noguchi et al.
To develop vaccine adjuvants from bacterial peptidoglycan (PG) the immunostimulatory activity of lysozyme-solubilized PG derived from Levilactobacillus brevis and Lactiplantibacillus plantarum was investigated. Solubilized PG from both bact...
OmpA_C-Like Domain of PorE Is Essential for PorE Function in the Type IX Secretion System (T9SS) of Porphyromonas gingivalis and Some T9SS Cargo Proteins Are Secreted in a PorE-Independent Manner [0.03%]
牙龈卟啉单胞菌PorE蛋白的OmpA_C结构域是T9SS分泌系统功能所必需的,并且某些通过T9SS分泌系统的效应物蛋白不需要PorE蛋白质参与而被分泌出来
Takashi Tominaga,Hideharu Yukitake,Paul D Veith et al.
Takashi Tominaga et al.
The periodontal pathogen Porphyromonas gingivalis secretes gingipains, highly hydrolytic proteases, to the cell surface or external environment via a type IX secretion system (T9SS). PorE is one of the T9SS component proteins essential for ...
Development of a Porcine Cell Line Stably Expressing Ephrin-B2 for Nipah Virus Research and Diagnostic Testing [0.03%]
用于尼帕病毒研究和诊断检测的稳定表达Ephrin-B2猪细胞系的建立
Hui Zhang,Akatsuki Saito
Hui Zhang
Nipah virus (NiV) is a highly pathogenic zoonotic virus transmitted from bats to humans through pigs as a crucial intermediate host. NiV outbreaks pose significant public health and economic threats, especially for pig farmers. Although the...
Administration of Lactiplantibacillus brownii Strain MH-1 During the Larval Stage Increases the Resistance Against Staphylococcus aureus subsp. aureus in Caenorhabditis elegans [0.03%]
芽孢杆菌MH-1株在幼虫阶段的管理增加了芽孢杆菌属亚种 aureus的耐受性蠕虫模型中的金黄色葡萄球菌_subsp
Mina Hashimoto,Yoshihiko Tanimoto,Eriko Kage-Nakadai
Mina Hashimoto
Lactiplantibacillus brownii is a new species of lactic acid bacteria discovered in sauerkraut in Russia, first reported in 2023. We previously isolated L. brownii strain MH-1 (MH-1) from homemade pickled Chinese cabbage in Japan and reporte...