Deep learning deciphers behavioral states from muscle activation patterns [0.03%]
深度学习从肌肉激活模式中解析行为状态
Honoka Kuroyanagi,Yuji Ikegaya,Nobuyoshi Matsumoto
Honoka Kuroyanagi
Accurate assessment of animal behavior is limited by manual video observation. Here, we demonstrate that deep learning-based analysis of multi-site electromyograms enables classification of behavioral states. Electromyograms were recorded f...
Postoperative administration of 2,5-dimethylcelecoxib attenuates ischemia-reperfusion injury-induced cardiac dysfunction [0.03%]
术后服用2,5-二甲基塞乐西布可减轻缺血再灌注损伤引起的心功能障碍
Shin Ishikane,Takehiro Kishigami,Eigo Ikushima et al.
Shin Ishikane et al.
Ischemia-reperfusion (I/R) following reperfusion therapy for ischemic heart disease is a driver of adverse cardiac remodeling and eventual heart failure. We investigated the therapeutic potential of 2,5-dimethylelcelecoxib (DM-C) to prevent...
S-allyl-l-cysteine ameliorates sensorimotor functions after intracerebral hemorrhage in mice concomitantly with prevention of axon tract fragmentation and reduction of brain lesion volume [0.03%]
S-烯丙基-L半胱氨酸通过防止神经纤维轨迹断裂和减少脑梗死体积来改善脑出血后的感觉和运动功能失调
Yuma Hirata,Keita Kinoshita,Keisuke Ushida et al.
Yuma Hirata et al.
Intracerebral hemorrhage (ICH) is a devastating type of stroke with high mortality and limited treatment options. Brain tissue injury featured by neuroinflammation and axonal damage plays a pivotal role in poor outcome. S-allyl-l-cysteine, ...
Protective role of early Tnfsf15 upregulation in limiting glomerular injury and proteinuria in experimental Alport Syndrome [0.03%]
早期Tnfsf15上调在实验性Alport综合征中限制肾小球损伤和蛋白尿的保护作用
Aimi Owaki,Shota Kaseda,Shunsuke Tanigawa et al.
Aimi Owaki et al.
Alport syndrome is a progressive kidney disease caused by pathogenic variants in genes encoding type IV collagen, a major structural component of the glomerular basement membrane (GBM). Abnormal GBM architecture impairs filtration and trigg...
Tacrolimus attenuates Th17 cell-mediated allergic skin inflammation in mice [0.03%]
他克莫司通过抑制Th17细胞减轻小鼠过敏性皮肤炎症反应
Fatemeh Beygom Mirkatouli,Yukiko Tao,Uyanga Enkhbaatar et al.
Fatemeh Beygom Mirkatouli et al.
Tacrolimus, a topical calcineurin inhibitor, is used to treat atopic dermatitis (AD). AD is classically T helper type (Th) 2-driven, but Th17 cells are implicated in chronic AD, yet its efficacy against Th17-dependent pathology remains uncl...
DHODH inhibition impairs mitochondrial function and extravillous trophoblast invasion: Protective roles of quercetin and riboflavin [0.03%]
DHODH抑制会损害线粒体功能和绒毛外滋养细胞侵袭：芦丁和核黄素的保护作用
Kanoko Yoshida,Kazuya Kusama,Kana Kanazawa et al.
Kanoko Yoshida et al.
Hypertensive disorders of pregnancy (HDPs) are serious complications that pose significant risks to both maternal and fetal health. In HDP, placental circulatory impairment is generally attributed to defective differentiation and invasion o...
Retraction notice to "Ameliorating effect of hypothalamic brain-derived neurotrophic factor against impaired glucose metabolism after cerebral ischemic stress in Mice" [J. Pharmacol. Sci. 118 (2012) 109-116] [0.03%]
有关《脑室内注射脑源性神经营养因子对脑缺血应激致糖代谢障碍小鼠的影响》的撤稿声明
Shinichi Harada,Wakako Fujita-Hamabe,Shogo Tokuyama
Shinichi Harada
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Authors. In Figure 1C some of...
Published Erratum
Journal of pharmacological sciences. 2020 Apr;142(4):176. DOI:10.1016/j.jphs.2020.02.002 2020
Retraction notice to "Effect of Orexin-A on post-ischemic glucose intolerance and neuronal damage" [J Pharmacol Sci 115 (2011) 155-163] [0.03%]
有关“下丘脑素A对缺血后糖耐量异常及神经元损伤的影响”的撤稿声明[J Pharmacol Sci 115 (2011) 155-163]
Shinichi Harada,Wakako Fujita-Hamabe,Shogo Tokuyama
Shinichi Harada
Published Erratum
Journal of pharmacological sciences. 2020 Jul;143(3):243. DOI:10.1016/j.jphs.2020.04.002 2020
Magnesium deficiency differentially modulates hippocampal and prefrontal oscillations and cardiac rhythms [0.03%]
镁缺乏对海马区和前额叶振荡及心脏节律有不同的调节作用
Sora Inoue,Yuji Ikegaya,Nobuyoshi Matsumoto et al.
Sora Inoue et al.
Magnesium (Mg) is an essential cation critical for neuronal and cardiac homeostasis, principally by modulating N-methyl-d-aspartate (NMDA) receptor function. While magnesium deficiency (MgD) is known to impair memory and autonomic function,...
Delayed response of the median raphe serotonin neurons projecting to the ventral hippocampus to aversive stimuli [0.03%]
投射到海马区的中缝背核5-HT神经元对厌恶刺激产生延迟反应
Hinako Morishita,Harune Hori,Hiroyuki Kawai et al.
Hinako Morishita et al.
Appropriate processing of aversive information is essential for survival. We previously demonstrated that serotonin neurons in the median raphe nucleus (MRN) play a key role in such processing; however, MRN responses to predictive cues of a...