Development of dectin-1-binding peptides targeting dendritic cells for antigen delivery via ribosome display [0.03%]
基于核糖体显示技术筛选树突细胞特异性结合的Dectin-1肽拮抗剂用于抗原递呈
Yoshirou Kawaguchi,Md Shahin Sarker,Mina Yokoyama et al.
Yoshirou Kawaguchi et al.
Dendritic cells (DCs) are professional antigen-presenting cells that play a central role in initiating and shaping adaptive immune responses. Targeting antigens to DCs has emerged as a promising strategy to enhance vaccine efficacy and tail...
Nevin McCone,Masahito Hosokawa
Nevin McCone
Single-cell genomics (SCG) complements culture-independent metagenomics for accessing fungal genomes, particularly from lineages that remain uncultured. We contrast metagenomics, which excels when profiling community composition and metabol...
Zein/Fucoidan microcarriers promote myogenic differentiation via topographical cues and hydrodynamic modulation [0.03%]
苔藓虫多糖/角蛋白微载体促进成肌分化的拓扑和流体动力学调节作用
Wanli Xiong,Chengxin Ge,Botao Zhang et al.
Wanli Xiong et al.
Microcarrier surface topography and fluid shear stress (FSS) critically regulate cellular behavior. An edible zein/fucoidan microcarrier with 200 μm grooves was designed for this study. Computational fluid dynamics (CFD) simulations and ex...
Spatial, temporal, and biotic changes in the natural abundances of stable carbon and nitrogen isotopes in a biological treatment reactor [0.03%]
生物处理反应器中稳定碳氮同位素自然丰度的时空和生物变化规律
Takashi Onodera,Kengo Kubota,Akinori Iguchi et al.
Takashi Onodera et al.
The natural abundances of stable isotopes were used to determine prey-predator relationships and material flows in a biological treatment reactor for municipal wastewater. The reactor used in this study was a down-flow hanging sponge (DHS),...
Using pure oxygen aeration to increase recombinant protein production by an Aspergillus oryzae hyphal dispersion strain [0.03%]
采用纯氧曝气提高米曲霉菌丝簇产生的重组蛋白产量
Satoshi Ishibashi,Shunya Susukida,Kiyoaki Muto et al.
Satoshi Ishibashi et al.
A high growth rate is essential for increasing protein production efficiency in liquid fermentation of filamentous fungi, such as Aspergillus oryzae. However, the increase in culture viscosity due to fungal growth constrains the overall yie...
Selective vanillate production from sugarcane bagasse-derived aromatic compounds using an engineered Pseudomonas sp. NGC7-based strain [0.03%]
一种利用改良的施氏假单胞菌NGC7系产生香草酸的方法
Md Jahangir Alam,Naoya Kodama,Kazuma Ikeda et al.
Md Jahangir Alam et al.
In this study, Pseudomonas sp. NGC7 was engineered to selectively produce vanillate (VA) from aromatic compounds in the sugarcane bagasse alkaline extract. A VA O-demethylase gene (vanA4B4)-disrupted strain derived from NGC7 grew and produc...
Mingdong Chang,Ru Yin,Jianqiao Wang et al.
Mingdong Chang et al.
The understanding of white-rot fungi (WRF) and their role in degrading recalcitrant environmental pollutants has significantly advanced due to developments in bioremediation research. Considerable progress has been made in elucidating the d...
One-pot synthesis of β-alanine from 1,3-diaminopropane using two-enzyme cascade in cell-free biotransformation [0.03%]
基于无细胞生物转化的1,3-二氨基丙烷两步酶法合成β-丙氨酸研究
Shanthi Shanmugasundaram,Anitha Janet Roshni Yesudhas,Andrea Kagoo et al.
Shanthi Shanmugasundaram et al.
A novel two-enzyme cascade one-pot synthesis of β-alanine from 1,3-diaminopropane (DAP) has been developed. In the first step, DAP was oxidized to 3-aminopropionaldehyde (3-APAL) by diamine oxidase (DAO). In the second step, 3-APAL was oxi...
Aerobic degradation characteristics of cis-1,2-dichloroethene by Pseudonocardia sp. D17: Degradation kinetics, putative degradation pathways, and involvement of soluble di-iron monooxygenases in the initial oxidation [0.03%]
反硝化链丝菌D17的好氧顺式-1,2-二氯乙烯降解特性：降解动力学、可能的降解途径及可溶性二价铁单加氧酶在初始氧化中的作用
Ryugo Nishimine,Yuna Kaneko,Shinpei Fujiwara et al.
Ryugo Nishimine et al.
Pseudonocardia sp. D17 (D17) is a novel strain capable of aerobically metabolizing cis-1,2-dichloroethene (cDCE), a persistent contaminant in soil and groundwater. This study aimed to investigate the cDCE degradation characteristics of D17 ...
Breeding bafilomycin A1-resistant sake yeast to improve fermentative capacity [0.03%]
通过酿酒酵母培育巴非洛霉素A1抗性菌株来提高发酵能力
Mai Nakase,Hiroyuki Senjyu,Takuya Asai et al.
Mai Nakase et al.
Sake yeast exhibits remarkable fermentative capacity in mash environments, even under various stress conditions. Although breeding techniques aimed at improving the flavor of sake by modifying aroma compounds and organic acid composition ha...