Pheochromocytoma associated with a succinate dehydrogenase subunit B mutation: A minireview and a case report [0.03%]
与琥珀酸脱氢酶亚基B基因突变相关的嗜铬细胞瘤：综述和病例报告
Emad Rezkallah,Andrew Elsaify,Victorino Martin et al.
Emad Rezkallah et al.
Objective. Pheochromocytomas and paragangliomas are rare neuroendocrine tumors that arise from the chromaffin cells of the adrenal medulla or extra-adrenal tissues. These tumors are characterized by an excessive secretion of catecholamines,...
A narrative review on pathogenetic mechanisms of hyperinsulinemic hypoglycemia in Kabuki syndrome [0.03%]
卡布基综合征胰岛素分泌过多性低血糖的发病机制综述
Evelina Maines,Arianna Maiorana,Letizia Leonardi et al.
Evelina Maines et al.
Objective. Kabuki syndrome (KS) is associated with hyperinsulinemic hypoglycemia (HH) in 0.3-4% of patients, thus exceeding the prevalence in the general population. HH association is stronger for KS type 2 (KDM6A-KS, OMIM #300867) than KS ...
Comparison of aspartate aminotransferase platelet ratio index score and insulin resistance in type 2 diabetes mellitus with non-alcoholic fatty liver disease [0.03%]
2型糖尿病合并非酒精性脂肪肝病患者天冬氨酸氨基转移酶血小板比率指数评分与胰岛素抵抗对比研究
Nikhil Gupta,Waseem Ramzaan Dar,Asma Wani et al.
Nikhil Gupta et al.
Objective. Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver diseases characterized by the presence of ectopic fat in the liver and steatosis, which cannot be explained by alcohol consumption. The association between NAFLD and...
Observational Study
Endocrine regulations. 2023 Jun 7;57(1):106-113. DOI:10.2478/enr-2023-0013 2023
Bugra Zengin,Burak Yuzuguldu,Ilgin Yildirim Simsir et al.
Bugra Zengin et al.
Objective. Besides the early detection and treatment of diabetic foot ulcers, being aware of the risk factors for major amputation plays a crucial role in preventing the major lower limb amputations. Major lower limb amputations are not jus...
IGF-1 and IGFBP3 as indirect markers of hepatic insulin resistance and their relation to metabolic syndrome parameters in liver steatosis patients [0.03%]
肝脂肪变性患者中的胰岛素抵抗的间接标志IGF-1和IGFBP3及其与代谢综合征参数的关系
Emil Fraenkel,Ivica Lazurova
Emil Fraenkel
Objective. The aim of the present study was to assess insulin-like growth factor 1 (IGF-1) and IGF-binding protein 3 (IGFBP3) as markers of insulin resistance in patients with prediabetes and type 2 diabetes mellitus (TDM2). Patients and Me...
Observational Study
Endocrine regulations. 2023 May 15;57(1):69-79. DOI:10.2478/enr-2023-0009 2023
Lipid accumulation product and visceral adiposity index: two indices to predict metabolic syndrome and insulin resistance in chronic kidney disease patients [0.03%]
脂质积聚产物和内脏脂肪指数：用于预测慢性肾脏病患者代谢综合征和胰岛素抵抗的两个指标
Ahmed Mohamed Fahmy,Nelly El Shall,Ibrahim Kabbash et al.
Ahmed Mohamed Fahmy et al.
Objective. Chronic kidney disease (CKD), metabolic syndrome (MetS) and insulin resistance (IR) are the major health problems associated with the increasing risk of cardiovascular and cerebrovascular complications. Methods. This cross-sectio...
Analysis of the association between anxiety, depression and obesity in individuals with metabolic syndrome [0.03%]
代谢综合征个体焦虑、抑郁和肥胖关联分析
Jamile das Virgens Silva,Claubert Radames O Coutinho-Lima,Najara Amaral Brandao et al.
Jamile das Virgens Silva et al.
Objective. The aim of this study was to verify the association between anxiety, depression, and obesity in metabolic syndrome (MetS) patients. Methods. It is a retrospective study with 142 volunteers with MetS of both genders and age ≥20 y...
Richard Imrich,Andrea Zatkova,Olga Lukacova et al.
Richard Imrich et al.
Alkaptonuria (AKU, OMIM, No. 203500) is a rare, slow-progressing, irreversible, multisystemic disease resulting from a deficiency of the homogentisate 1,2-dioxygenase enzyme, which leads to the accumulation of homogentisic acid (HGA) and su...
Identification of DNA methylation change in TCF7L2 gene in the blood of type 2 diabetes mellitus as a predictive biomarker in Iraq Kurdistan region by using methylation-specific PCR [0.03%]
TCF7L2基因甲基化变化作为伊拉克库尔德斯坦地区2型糖尿病预测生物标志物的识别研究-使用甲基化特异性PCR检测外周血中的差异
Harem Othman Smail,Dlnya Asaad Mohamad
Harem Othman Smail
Objective. Nowadays, type 2 diabetes mellitus (T2D) is the most common chronic endocrine disorder affecting an estimated 5-10% of adults worldwide, and this disease also rapidly increased among the population in the Kurdistan region. This r...
Insulin receptor substrate-1 gene polymorphism and lipid panel data in type 2 diabetic patients with comorbid obesity and/or essential hypertension [0.03%]
胰岛素受体底物-1基因多态性与2型糖尿病合并肥胖和/或原发性高血压患者的血脂谱数据
Mariya Marushchak,Lyudmyla Mazur,Inna Krynytska
Mariya Marushchak
Objective. The hallmarks of type 2 diabetes mellitus (T2DM) are insulin resistance (IR) and insulin receptor substrate (IRS) proteins essential for the insulin signaling. IRS-1 gene has not only been shown to be associated with T2DM, but al...