Hypoxia controls the expression of genes responsible for serine synthesis in U87MG cells on ERN1-dependent manner [0.03%]
缺氧通过ERN1依赖性方式控制U87MG细胞丝氨酸合成基因的表达
Myroslava Y Sliusar,Dmytro O Minchenko,Olena O Khita et al.
Myroslava Y Sliusar et al.
Objective. Serine synthesis as well as endoplasmic reticulum stress and hypoxia are important factors of malignant tumor growth including glioblastoma. Previous studies have shown that the knockdown of ERN1 (endoplasmic reticulum to nucleus...
Sana Rafaqat,Aqsa Sattar,Amber Khalid et al.
Sana Rafaqat et al.
Diabetes mellitus is characterized by hyperglycemia and abnormalities in insulin secretion and function. This review article focuses on various liver parameters, including albumin, alanine aminotransferase (ALT), aspartate aminotransferase ...
Effect of the GHRL gene (rs696217) polymorphism on the metabolic disorders in patients with obesity in the Ukrainian population [0.03%]
GHRL基因多态性(rs696217)对乌克兰肥胖人群代谢异常的影响
Andrii Prodan,Ihor Dzubanovsky,Oleksandr Kamyshnyi et al.
Andrii Prodan et al.
Objective. Over the past four decades, the prevalence of obesity has tripled and limited genetic studies with specific SNPs have been conducted, but no investigations using ghrelin and obestatin prepropeptide (GHRL) gene have been reported ...
Expression of selected nuclear receptors in human epithelial ovarian cell line Caov3 exposed to bisphenol derivatives [0.03%]
双酚类衍生物诱导人卵巢上皮癌细胞系Caov3中核受体的表达变化
Alzbeta Bujnakova Mlynarcikova,Dana Macejova,Sona Scsukova
Alzbeta Bujnakova Mlynarcikova
Objectives. Bisphenol A (BPA) is an indispensable industrial chemical. However, as a proven endocrine disruptor, it may be associated with several health disturbances, including the reproductive functions impairment and cancer. Due to the r...
Correlation between the size of pheochromocytoma and the level of metanephrines [0.03%]
嗜铬细胞瘤大小与血、尿儿茶酚胺代谢产物甲氧基肾上腺素类物质水平的关系研究
Emad Rezkallah,Andrew Elsaify,Ragai Hanna et al.
Emad Rezkallah et al.
Objective. Pheochromocytomas (PHEO) and paraganglioma (PGLs) are rare neuroendocrine catecholamine-producing tumors that arise from the chromaffin cells of either the adrenal medulla or extra-adrenal paraganglionic tissues. Despite the rece...
Effects of antipsychotics, haloperidol and olanzapine, on the expression of apoptosis-related genes in mouse mHippoE-2 cells and rat hippocampus [0.03%]
氟哌啶醇和奥氮平对小鼠mHippoE-2细胞和大鼠海马凋亡相关基因表达的影响
Jana Osacka,Alexander Kiss,Zuzana Bacova et al.
Jana Osacka et al.
Objective. Modified levels of pro- (caspase3, Bax) and anti-apoptotic (Bcl-2) regulatory proteins have been detected in certain brain areas of schizophrenic patients indicating a possible dysregulation of apoptosis. In the present study, ef...
Expression of DNAJB9 and some other genes is more sensitive to SWCNTs in normal human astrocytes than glioblastoma cells [0.03%]
DNAJB9和其他一些基因在正常人类星形胶质细胞中对SWCNTs的反应比胶质母细胞瘤细胞更敏感
Dmytro O Minchenko,Olha V Rudnytska,Olena O Khita et al.
Dmytro O Minchenko et al.
Objective. Single-walled carbon nanotubes (SWCNTs) are considered to be one of the nanomaterials attractive for biomedical applications, particularly in the health sciences as imaging probes and drug carriers, especially in the field of can...
Metabolic disorders during endogenous Cushing's syndrome: prevalence, associated factors, and outcome after remission [0.03%]
库欣综合征内源性发病时的代谢紊乱：流行病学特征、相关因素及痊愈后的预后情况
Melika Chihaoui,Ibtissem Oueslati,Nadia Khessairi et al.
Melika Chihaoui et al.
Objective. The prognosis of Cushing's syndrome (CS) is related to a higher cardiovascular morbidity and mortality. This study aimed to determine the prevalence of metabolic disorders in patients with CS, the associated factors, and the rate...
Efficacy and safety of SGLT2 inhibitors in individuals with type 1 diabetes under continuous subcutaneous insulin infusion: a real-world study [0.03%]
德谷胰岛素在1型糖尿病患者中与中国居民饮食指南推荐一致的碳水化合物饮食的比较：一项真实世界研究
Vania Benido Silva,Liliana Fonseca,Diana Borges Duarte et al.
Vania Benido Silva et al.
Objective. Adjuvant therapy with sodium-glucose cotransport 2 inhibitors (SGLT2i) in type 1 diabetes (T1D) is associated with an improvement in glycemic control, but increases the risk of diabetic ketoacidosis (DKA). However, real-life stud...
Anemia types in hypothyroid patients in a Coimbatore tertiary care hospital: A prospective observational study [0.03%]
印度科因卜图尔一家三级医院甲状腺功能减退患者贫血类型的一项前瞻性观察研究
Priyanka Sasidharan,Yoganathan Chidambaram,Bhargavi Kumar et al.
Priyanka Sasidharan et al.
Objective. Hypothyroidism is a syndrome characterized by clinical manifestations associated with thyroid hormone deficiency. The thyroid hormone plays a pivotal role in the hematopoietic system and stimulates precursors of erythropoietin ge...
Observational Study
Endocrine regulations. 2023 Jun 7;57(1):114-120. DOI:10.2478/enr-2023-0014 2023