Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells [0.03%]
骨髓间充质干细胞与睾丸细胞共培养分化的雄性生殖细胞样细胞研究
Nasim Malekmohamadi,Alireza Abdanipour,Mehrdad Ghorbanlou et al.
Nasim Malekmohamadi et al.
Objective: Stem cell therapy, specifically, pre-induction of mesenchymal stem cells toward male germ-like cells may be useful in patients with azoospermia. The aim of this study was to evaluate in vitro differentiation of...
Insulin resistance in obese adolescents affects the expression of genes associated with immune response [0.03%]
肥胖青少年的胰岛素抵抗影响与免疫反应相关的基因表达
Dmytro O Minchenko
Dmytro O Minchenko
Objective: The development of obesity and its metabolic complications is associated with dysregulation of various intrinsic mechanisms, which control basic metabolic processes through changes in the expression of numerous...
Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance [0.03%]
肥胖且具有胰岛素抵抗的青少年血液中IGF1、IGF2和IGFBPs编码基因表达式的调查研究
Dmytro O Minchenko,Dariia O Tsymbal,Vadim V Davydov et al.
Dmytro O Minchenko et al.
Objective: The development of obesity and its metabolic complications is associated with dys-regulation of various intrinsic mechanisms, which control basic metabolic processes via changes in the expression of numerous re...
Evaluation of ameliorative effect of sodium nitrate in experimental model of streptozotocin-induced diabetic neuropathy in male rats [0.03%]
评估硝酸钠对链脲佐菌素诱导的雄性大鼠糖尿病神经病变的改善作用评价
Hajar Oghbaei,Mohammad Reza Alipour,Gisou Mohaddes et al.
Hajar Oghbaei et al.
Objective: Diabetes induces sensory symptoms of neuropathy as positive (hyperalgesia), negative (hypoalgesia), or both. Methods: In the...
Lack of association between TCF7L2 gene variants and type 2 diabetes mellitus in a Brazilian sample of patients with the risk for cardiovascular disease [0.03%]
TCF7L2基因变异与巴西心血管病高危患者中2型糖尿病无相关性
Camile Wunsch,Thais Fernanda Dornelles,Pricila Girardi et al.
Camile Wunsch et al.
Objective: Genetic variants in the transcription factor 7-like 2 (TCF7L2) gene have been described as the most noteworthy ones regarding the type 2 diabetes mellitus (T2DM) liability. This work is aimed to evaluate the as...
Neuronal morphology alterations in autism and possible role of oxytocin [0.03%]
自闭症相关的神经元形态改变及其可能的催产素调节机制
Hisham El Falougy,Barbora Filova,Daniela Ostatnikova et al.
Hisham El Falougy et al.
Current understanding of the neuroanatomical abnormalities in autism includes gross anatomical changes in several brain areas and microstructural alterations in neuronal cells as well. There are many controversies in the interpretation of t...
The effect of peptide tyrosine tyrosine (PYY3-36), a selective Y2 receptor agonist on streptozotocin-induced diabetes in albino rats [0.03%]
肽酪氨酸酪氨酸(PYY3-36)，一种选择性Y2受体激动剂对链脲佐菌素致肥胖仓鼠糖尿病的作用
Heba A Abdel-Hamid,Mona M I Abdalla,Nagwa M Zenhom et al.
Heba A Abdel-Hamid et al.
Objective: The aim of the present study was to assess the effect of the PYY3-36, as a potential therapy for the type 2 diabetes mellitus (T2DM), induced by high fat diet (HFD) and an intraperitoneal (i.p.) administration ...
One-month of high-intensity exercise did not change the food intake and the hypothalamic arcuate nucleus proopiomelanocortin and neuropeptide Y expression levels in male Wistar rats [0.03%]
高强度一个月运动未改变Wister大鼠的摄食量以及下丘脑弓状核促黑激素和神经肽Y表达水平
Nazli Khajehnasiri,Homayoun Khazali,Farzam Sheikhzadeh et al.
Nazli Khajehnasiri et al.
Objective: The hypothalamic arcuate nucleus proopiomelanocortin (POMC) and neuropeptide Y (NPY) circuitries are involved in the inhibition and stimulation of the appetite, respectively. The aim of this study was to invest...
Dampening of neurotransmitter action: molecular similarity within the melatonin structure [0.03%]
神经传递素作用的抑制：褪黑激素结构内的分子相似性
Wynford R Williams
Wynford R Williams
Objectives: Melatonin initiates physiologic and therapeutic responses in various tissues through binding to poorly defined MT receptors regulated by G-proteins and purine nucleotides. Melatonin's interaction with other G-...
Enhanced intestinal 2-deoxy-2-[18F]fluoro-D-glucose uptake under metformin is not fully suppressed by loperamide [0.03%]
二甲双胍增强的肠黏膜2-脱氧-2-[18F]氟-D-葡萄糖摄取不能被洛哌amide完全抑制
Tomomi Nobashi,Tsuneo Saga,Yuji Nakamoto et al.
Tomomi Nobashi et al.
Objective: This study investigated whether the metformin (Met)-induced enhanced intestinal uptake of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) is reduced by loperamide, a long-acting anti-diarrheal agent. ...