Ulmus minor bark hydro-alcoholic extract ameliorates histological parameters and testosterone level in an experimental model of PCOS rats [0.03%]
elmiumin皮氢醇提取物对实验性多囊卵巢综合征大鼠组织学参数及睾酮水平的影响
Mohammad Javad Hoseinpour,Alireza Ghanbari,Nahid Azad et al.
Mohammad Javad Hoseinpour et al.
Objective: Polycystic ovary syndrome (PCOS) is a common and multifactorial disease associated with female factor infertility. Ulmus minor bark (UMB) is one of the medicinal plants used in Persian folklore as a fertility e...
Pheochromocytoma [0.03%]
嗜铬细胞瘤
Frederick-Anthony Farrugia,Anestis Charalampopoulos
Frederick-Anthony Farrugia
Pheochromocytomas are rare tumors originating in the adrenal medulla. They may be sporadic or in the context of a hereditary syndrome. A considerable number of pheochromocytomas carry germline or somatic gene mutations, which are inherited ...
Sex and salt intake dependent renin-angiotensin plasticity in the liver of the rat [0.03%]
大鼠肝脏中性激素和食盐摄入量对肾素血管紧张素系统的调节作用
Paulina Pidikova,Pavel Svitok,Iveta Herichova
Paulina Pidikova
Objective: Epidemiological studies confirm that hypertensive patients respond differently to renin-angiotensin system (RAS) inhibition depending on their gender. The aim of present work is to focus on sex-dependent differ...
Aldosterone rapidly activates p-PKC delta and GPR30 but suppresses p-PKC epsilon protein levels in rat kidney [0.03%]
醛固酮快速激活大鼠肾脏中的p-PKC delta和GPR30但抑制p-PKC epsilon蛋白水平
Somchit Eiam-Ong,Mookda Chaipipat,Krissanapong Manotham et al.
Somchit Eiam-Ong et al.
Objectives: Aldosterone rapidly enhances protein kinase C (PKC) alpha and beta1 proteins in the rat kidney. The G protein-coupled receptor 30 (GPR30)-mediated PKC pathway is involved in the inhibition of the potassium cha...
Efficacy and safety of dulaglutide in patients with absolute insulin deficiency [0.03%]
德谷胰岛素在绝对性胰岛素缺乏患者中的疗效和安全性研究
Eiji Kutoh,Jyunka Hayashi,Alexandra N Kuto
Eiji Kutoh
Objective: While dulaglutide has been approved inpatients with type 2 diabetes (T2DM) in combination with insulin, it has not been studied in insulin-deficient patients, not whether they have type 1 diabetes (T1DM) or T2D...
Clinical Trial
Endocrine regulations. 2019 Jul 1;53(3):187-190. DOI:10.2478/enr-2019-0019 2019
Enkephalinase activity is modified and correlates with fatty acids in frontal cortex depending on fish, olive or coconut oil used in the diet [0.03%]
脑啡肽酶活性的改变及其与皮层脂肪酸的相关性取决于饮食中使用鱼类、橄榄或椰子油
Ana B Segarra,Isabel Prieto,Magdalena Martinez-Canamero et al.
Ana B Segarra et al.
Objective: Enkephalins are neuropeptides involved in functions such as pain modulation and/ or cognitive processes. It has been reported that dietary fat modifies enkephalins in the brain. Since enkephalins are hydrolyzed...
Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer's disease in the mice brain cortex [0.03%]
单次束缚或脂多糖刺激可增加小鼠大脑皮层中与阿尔茨海默病发生发展相关基因的表达
Alexandra Padova,Ivana Rokytova,Boris Mravec et al.
Alexandra Padova et al.
Objectives: Despite extensive research efforts, mechanisms participating on development of Alzheimer's disease (AD) are covered only partially. Data from the last decades indicate that various stressors, as etiological fa...
Clozapine impact on FosB/ΔFosB expression in stress preconditioned rats: response to a novel stressor [0.03%]
氯氮平对压力预处理大鼠FosB / ΔFosB 表达的影响：对新型应激原的反应
Jana Osacka,Lubica Horvathova,Alena Cernackova et al.
Jana Osacka et al.
Objective: Prolonged treatment with neuroleptics has been shown to induce FosB/ΔFosB expression in several brain regions including the medial prefrontal cortex, dorsomedial and dorsolateral striatum, ventrolateral and do...
Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat's bone marrow stromal cells [0.03%]
胃饥饿素通过PI3激酶信号途径诱导大鼠骨髓基质细胞HoxB4基因的表达
Shokoufeh Taherkhani,Fatemeh Moradi,Masoumeh Hosseini et al.
Shokoufeh Taherkhani et al.
Objective: Ghrelin, a 28 amino acid peptide, has diverse physiological roles. Phosphatidylino-sitol-bisphosphate 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) are involved in some of the recognized actions o...
Terezia Valkovicova,Martina Skopkova,Juraj Stanik et al.
Terezia Valkovicova et al.
MODY (Maturity Onset Diabetes of the Young) is a type of diabetes resulting from a pathogenic effect of gene mutations. Up to date, 13 MODY genes are known. Gene HNF1A is one of the most common causes of MODY diabetes (HNF1A-MODY; MODY3). T...