Metabolomic-genomic prediction realizes small increases in accuracy of estimated breeding values for daily gain in pigs [0.03%]
代谢组-基因组预测可小幅提高猪平均日增重表型育种值的估计准确性
Xiangyu Guo,Pernille Sarup,Anders Bay Nord et al.
Xiangyu Guo et al.
Background: Metabolomic profiling of blood samples can be done on selection candidates and could be a valuable information source for genetic evaluation of pigs. We hypothesized that integrating metabolomic data from pigs...
A bovine model of rhizomelic chondrodysplasia punctata caused by a deep intronic splicing variant in the GNPAT gene [0.03%]
GNPAT基因深层内含子剪接变异所致远端肢体畸形软骨发育不良点状小体病的牛模型
Arnaud Boulling,Julien Corbeau,Cécile Grohs et al.
Arnaud Boulling et al.
Background: Genetic defects that occur naturally in livestock species provide valuable models for investigating the molecular mechanisms underlying rare human diseases. Livestock breeds are subject to the regular emergenc...
Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs [0.03%]
伊比利亚猪和杜洛克猪味觉受体基因的表达及结构分析
Cristina Óvilo,Rita Benítez,Yolanda Núñez et al.
Cristina Óvilo et al.
Background: Taste receptor genes are expressed in sensory cells located in the tongue and influence food preferences, voluntary feed intake, and other relevant traits. Taste perception may differ between livestock breeds ...
Estimating mutation rate and characterising single nucleotide de novo mutations in pigs [0.03%]
猪的突变率估计及其新生单核苷酸突变特征分析
Christina M Rochus,Marije J Steensma,Marco C A M Bink et al.
Christina M Rochus et al.
Background: Direct estimates of mutation rates in humans have changed our understanding of evolutionary timing and de novo mutations (DNM) have been associated with several developmental disorders in humans. Livestock spe...
Comparison of genomic prediction accuracies in dairy cattle lactation traits using five classes of functional variants versus generic SNP [0.03%]
基于五类功能性变异和通用SNP的奶牛乳用性状基因组预测准确度比较研究
Setegn Worku Alemu,Thomas J Lopdell,Alexander J Trevarton et al.
Setegn Worku Alemu et al.
Background: Genomic selection, typically employing genetic markers from SNP chips, is routine in modern dairy cattle breeding. This study assessed the impact of functional sequence variants on genomic prediction accuracy ...
Comparative Study
Genetics, selection, evolution : GSE. 2025 Apr 11;57(1):20. DOI:10.1186/s12711-025-00966-2 2025
Quantitative genetic analysis of late spring mortality in triploid Crassostrea virginica [0.03%]
三倍体金刚蛤幼虫迟发性春夏季死亡的定量遗传分析
Joseph L Matt,Jessica Moss Small,Peter D Kube et al.
Joseph L Matt et al.
Background: Triploid oysters, bred by crossing tetraploid and diploid oysters, are common worldwide in commercial oyster aquaculture and make up much of the hatchery-produced Crassostrea virginica farmed in the mid-Atlant...
Analysis of different genotyping and selection strategies in laying hen breeding programs [0.03%]
不同基因分型和选择策略在蛋鸡育种项目中的分析
Lisa Büttgen,Henner Simianer,Torsten Pook
Lisa Büttgen
Background: Genomic selection has become an integral component of modern animal breeding programs, having the potential to improve the efficiency of layer breeding programs both by obtaining higher prediction accuracies a...
SIRE 2.0: a novel method for estimating polygenic host effects underlying infectious disease transmission, and analytical expressions for prediction accuracies [0.03%]
SIRE 2.0：一种估计传染病传播背景下多基因宿主效应的新方法及其预测准确性的解析表达式
Christopher M Pooley,Glenn Marion,Jamie Prentice et al.
Christopher M Pooley et al.
Background: Genetic selection of individuals that are less susceptible to infection, less infectious once infected, and recover faster, offers an effective and long-lasting solution to reduce the incidence and impact of i...
High performance imputation of structural and single nucleotide variants using low-coverage whole genome sequencing [0.03%]
利用低覆盖率全基因组测序高效地填补结构变异和单核苷酸变异
Manu Kumar Gundappa,Diego Robledo,Alastair Hamilton et al.
Manu Kumar Gundappa et al.
Background: Whole genome sequencing (WGS), despite its advantages, is yet to replace methods for genotyping single nucleotide variants (SNVs) such as SNP arrays and targeted genotyping assays. Structural variants (SVs) ha...
Multitrait genome-wide association best linear unbiased prediction of genetic values [0.03%]
多性状全基因组关联最佳线性无偏预测遗传值
Theo Meuwissen,Vinzent Boerner
Theo Meuwissen
Background: The GWABLUP (Genome-Wide Association based Best Linear Unbiased Prediction) approach used GWA analysis results to differentially weigh the SNPs in genomic prediction, and was found to improve the reliabilities...