Genomic solutions to metadata challenges: a case study on the 1000 Bull Genomes Project [0.03%]
基因组解决方案应对元数据挑战：1000头公牛基因组项目的案例研究
Johanna-Sophie Schlüter-Bartram,Felix Heinrich,Mehmet Gültas et al.
Johanna-Sophie Schlüter-Bartram et al.
Background: Advancements in sequencing technologies have led to an unprecedented availability of whole-genome sequencing data in all life sciences, including livestock research. However, this raises concerns regarding the...
Quantitative genetic analyses of traits related to calcium and phosphorus metabolism in two different laying hen strains [0.03%]
两个不同品系产蛋鸡与钙、磷代谢性状的定量遗传分析
Valentin P Haas,Markus Schmid,Vera Sommerfeld et al.
Valentin P Haas et al.
Background: Phosphorus (P) and calcium (Ca) are essential minerals for laying hens. Phosphorus in plant feeds is mainly stored as phytate and needs to be released by the enzyme phytase. Due to the high requirement of Ca, ...
Heat-load-dependent inbreeding depression for production traits in Italian Holstein cattle [0.03%]
意大利荷斯坦牛生产性状的热量负荷依赖的近交衰退现象
Francesco Tiezzi,Joao Claudio do Carmo Panetto,Simone Callegaro et al.
Francesco Tiezzi et al.
Background: The objective of this study was to test whether the negative effects of inbreeding on production traits varied according to the level of environmental load. Traits analyzed were milk, fat, and protein yields, ...
A non-linear game for two: genetic parameters and prediction of fertilization success using Bayesian and machine learning frameworks [0.03%]
基于贝叶斯和机器学习框架的两性非线性博弈：遗传参数及受精成功率预测
Fotis Pappas,Paul Vincent Debes,Martin Johnsson et al.
Fotis Pappas et al.
Fertility is an important but often cryptic and intrinsic characteristic of domesticated animals. Predicting reproductive potential is of great importance for the industry but assessment through indirect proxies is laborious and often impra...
Impact of QTL number, heritability and reference population size on the benefit of machine learning models over GBLUP in genomic prediction [0.03%]
数量性状位点数目、遗传力和参考群体大小对机器学习模型在基因组预测中相对于GBLUP的优势的影响
Jifan Yang,Yvonne C J Wientjes,Mario P L Calus et al.
Jifan Yang et al.
Background: With the successful application of machine learning (ML) in many areas, its potential for genomic prediction (GP) in animal and plant breeding has attracted growing attention. However, despite numerous studies...
A regulatory 24-bp insertion at the BCO2 gene region is associated with yellow skin in chickens [0.03%]
家鸡皮肤变黄与BCO2基因区域的调控插入序列有关
Li Rong,Xueying Wu,Jiao Li et al.
Li Rong et al.
Background: Chicken skin colour is an economically important trait influenced by consumer preferences across different markets. Previous studies established that white skin is dominant over yellow skin, with the β, β-ca...
Optimisation of selection for methane mitigation by integrating production traits with ruminal microbiome-driven breeding in beef cattle [0.03%]
通过整合生产性状和瘤胃微生物组驱动育种优化甲烷减排选择育种效果-肉牛案例分析
Tuan Q Nguyen,Marina Martínez-Álvaro,Joana Lima et al.
Tuan Q Nguyen et al.
Background: Breeding for reduced methane production is challenged by the high cost associated with its continuous measurements on individual animals. To address this, a microbiome-driven breeding methodology was developed...
Genomic dissection of hoof and leg conformation in Swiss dairy cattle populations reveals polygenic architecture and a recessive HYAL1 nonsense variant affecting longevity in Holstein cattle [0.03%]
对瑞士奶牛种群蹄和腿形态的基因组分析揭示了多基因结构以及HOUSTON1无义变异影响荷斯坦奶牛长寿的隐性变异
Stefan Vasiljevic,Franz R Seefried,Sarah Widmer et al.
Stefan Vasiljevic et al.
Background: The genetic architecture of bovine hoof and leg conformation traits remains incompletely understood, particularly in dairy cattle and with respect to non-additive effects. Moreover, the limited genetic resolut...
The mitogenome diversity of Alpine Rendena cattle: new clues on its maternal origin and the complex substructure of haplogroup T3 [0.03%]
阿尔卑斯山伦德纳奶牛线粒体基因组多样性：对其母系起源及T3谱系亚结构的新见解
Irene Cardinali,Anna Tommasi,Giacomo Villani et al.
Irene Cardinali et al.
Background: Val Rendena, an isolated Alpine valley in northern Italy, is home to an autochthonous, dual-purpose cattle breed with unique historical and morphological traits, which has been preserved by local breeders desp...
Genomic partitioning and functional dissection of inbreeding depression for stature in Brown Swiss cattle [0.03%]
基因组划分和布朗瑞士牛长势近交衰退的功能分析
Qiongyu He,Jessica Deuber,Franz R Seefried et al.
Qiongyu He et al.
Background: Small effective population size and the disproportionately large use of few genetically superior bulls in artificial insemination lead to extensive runs of homozygosity and an increased risk of homozygosity fo...