Immunohistochemical expression and association of hypoxia-inducible factor 1a and carbonic anhydrase IX in colorectal cancer [0.03%]
缺氧诱导因子-1α和碳酸酐酶IX在结直肠癌中表达及关系的免疫组化研究
Veronika Cígerová,Marian Adamkov,Marián Grendár et al.
Veronika Cígerová et al.
The presented work focuses on hypoxia-inducible factor 1a (HIF-1a) and carbonic anhydrase IX (CA IX) in colorectal cancer (CRC). The HIF-1a protein shows increased expression due to hypoxia, resulting in up-regulation of CA IX, which is inv...
Expression of C-terminal tensin-like in breast carcinoma and its correlation with known prognostic factors [0.03%]
乳腺癌中C末端张力蛋白样分子的表达及其与预后因素的相关性研究
Usma Arshad,Syeda Fatima Rizvi,Shahzada Khalid Sohail et al.
Usma Arshad et al.
C-terminal tensin-like (Cten) is a marker for poorly differentiated breast cancer. We evaluated the immunohistochemical expression of Cten in invasive breast carcinoma in our population and correlated it with known histopathologic prognosti...
Does SOX-2 expression have a prognostic value in triple-negative breast cancer? [0.03%]
SOX-2表达在三阴性乳腺癌中的预后价值分析
Ismail Guzelis,Betul Bolat Kucukzeybek,Merve Gursoy et al.
Ismail Guzelis et al.
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. At the cell of origin level, cancer stem cells (CSC) are the tumour initiators in breast cancer. SRY-box transcription factor 2 (SOX-2) is a CSC marker th...
Giant low-grade myofibroblastic sarcoma of the male breast: case report and literature review [0.03%]
男性乳房低级别肌纤维母细胞肉瘤巨块型病例报告及文献复习
Shiwei Xiao,Hongtao Chen,Juan Xu et al.
Shiwei Xiao et al.
Low-grade myofibroblastic sarcoma is an uncommon malignancy that can be difficult to identify and for which there is no unified treatment protocol. We report herein a case of an 81-year-old male who presented with a giant irregular breast m...
The impact of KRAS mutations on the tumour microenvironment and treatment response in non-small cell lung cancer [0.03%]
KRAS突变对非小细胞肺癌肿瘤微环境和治疗反应的影响
Guomin Gu,Chunling Liu,Yan Yang et al.
Guomin Gu et al.
Mutations in the KRAS gene in non-small cell lung cancer (NSCLC) are common drivers. Gene expression and mutation data of NSCLC were collected from the TCGA dataset. DEGs between KRAS mutations and wild type were identified, and enrichment ...
Fat mass and obesity-associated protein expression in colorectal cancer and its influence on the biological behaviour of colorectal cancer cells [0.03%]
脂肪质量与肥胖相关蛋白在结直肠癌的表达及其对结直肠癌细胞生物学行为的影响
Huihui Wu,Yibo Wu,Zhishan Zhang et al.
Huihui Wu et al.
Fat mass and obesity-associated protein (FTO) was the earliest discovered m6A RNA demethylase. Previous studies have indicated that m6A modifications significantly influence the development, progression, and prognosis of various cancers. Th...
Clinicopathological importance of immunohistochemical expression of OCT4, c-MYC and Ki-67 in colorectal cancer [0.03%]
OCT4、c-MYC和Ki-67在结直肠癌免疫组化表达的临床病理意义
Rabia Hursitoglu,Abdulkadir Yasir Bahar,Sezen Koçarslan et al.
Rabia Hursitoglu et al.
Cancer stem cells (CSCs) are cancer cells responsible for cancer initiation, growth, metastasis, recurrence and resistance to treatment. OCT4 and c-MYC are widely accepted as CSC markers. In this study, we examined the immunohistochemical c...
LncRNA-PVT1 enhances glucose metabolism of pediatric low-grade glioma cells through sponging miR-187-3p [0.03%]
长链非编码RNA-PVT1通过吸附miR-187-3p增强儿童低级别胶质瘤细胞的葡萄糖代谢
Beibei Li,Zijian Feng,Yanyan Zheng
Beibei Li
Pediatric low-grade glioma (PLGG) is a heterogeneous group of primary central nervous system malignancies which represent the most frequent brain tumors in children. Although diagnosis and treatment of PLGG have been improved recently, the ...
Morphological and immunohistochemical analysis in encapsulated follicular variant papillary thyroid carcinoma, invasive follicular variant papillary thyroid carcinoma and a new entity: non-invasive follicular thyroid neoplasm with papillary nuclear feature [0.03%]
包膜包裹的滤泡型乳头状甲状腺癌、侵袭性滤泡型乳头状甲状腺癌及一个新的实体：具有乳头核特征的非侵袭性滤泡性甲状腺肿瘤的形态学和免疫组化分析
Zeliha Çelik,Naile Kökbudak,Fahriye Kilinç et al.
Zeliha Çelik et al.
Thyroid cancers are the most common endocrine organ cancers. Encapsulated follicular variant papillary thyroid carcinomas (EFVPTC) are quite slow (indolent). Non-invasive follicular thyroid neoplasm with papillary nuclear feature (NIFTP) is...
Epithelial mesenchymal transition and cancer stem cell markers in oral epithelial dysplasia and oral squamous cell carcinoma [0.03%]
口腔黏膜上皮内瘤变和口腔鳞癌中上皮间质转化及肿瘤干细胞标志物的研究
Burcu Tokozlu,Özlem Özer Yücel,Sibel E Gültekin et al.
Burcu Tokozlu et al.
The role of cancer stem cells (CSC) in oral cancer is widely accepted. Yet, the existence of CSC in dysplastic tissue and the molecular pathways of progression from dysplasia to malignancy remain to be explored. Our retrospective study aime...