Clinicopathological and molecular features of non-small cell lung cancer that transform to small-cell lung cancer: Case reports and literature review [0.03%]
非小细胞肺癌转化成小细胞肺癌的临床病理和分子特征：病例报告及文献综述
Qiqi Gao,Lixin Zhang,Yulong Zheng
Qiqi Gao
The purpose of this study is to explore the clinical and pathological characteristics as well as the molecular pathogenesis of patients with non-small cell lung cancer (NSCLC) transforming into small cell lung cancer (SCLC). We investigated...
Does loss of ARID1A expression affect neoadjuvant chemoradiotherapy response in rectal carcinomas? [0.03%]
ARID1A表达缺失影响低位直肠癌新辅助放化疗疗效吗？
Nagehan O Barisik,Sibel Sensu,Sevinc H Keser et al.
Nagehan O Barisik et al.
This study evaluated the difference of ARID1A protein immunoexpression between responders and non-responders to neoadjuvant chemoradiotherapy in locally advanced rectal cancers. The biopsies before neoadjuvant chemoradiotherapy and resectio...
FOXC1 expression profile in invasive breast carcinomas and its relationship with prognostic parameters [0.03%]
FOXC1在侵袭性乳腺癌中的表达及其与预后参数的关系研究
Özge Bozkurt Öztürk,Remzi Arslan
Özge Bozkurt Öztürk
This study aimed to investigate the expression profile of FOXC1 in molecular sub-types of invasive breast cancer. Additionally, it sought to explore the association between FOXC1 expression and clinicopathological prognostic parameters to e...
Thoracic SMARCA4-deficient undifferentiated tumour - a case of an aggressive neoplasm [0.03%]
胸主动脉SMARCA4缺陷型未分化肿瘤-一例侵袭性肿瘤的病例报告
Gizem Teoman
Gizem Teoman
SMARCA4-deficient undifferentiated tumours exhibit undifferentiated and rhabdoid features. These highly aggressive neoplasms pose significant diagnostic challenges. They are characterised by an inactivating mutation of SMARCA4, leading to t...
Malignant transformation of the epithelial component of a Warthin tumour into adenocarcinoma [0.03%]
沃汀瘤上皮成分恶性变腺癌化
WenBin Gou,BeiWen Song,KeJia Tong et al.
WenBin Gou et al.
To study the clinicopathological features of malignant transformation of the epithelial component of a Warthin tumour into adenocarcinoma. The histological and immunophenotypic features of the malignant transformation of the epithelial comp...
Coexistence of head and face Merkel cell and squamous cell carcinomas in the elderly population - a case report and literature review [0.03%]
老年人同时发生头部和面部的梅克尔细胞癌和鳞状细胞癌的病例报告及文献回顾
Shiwei Zhang,Hongliang Ji,Pan Qin
Shiwei Zhang
Merkel cell carcinoma (MCC) is a rare and highly aggressive neuroendocrine cancer type that predominantly impacts sun-exposed skin areas in the elderly, particularly the head and neck (41-50%), followed by the limbs (32-38%). There is likel...
Assessment of the status of DNA mismatch repair proteins by immunohistochemistry. Proposal for evaluation with two antibodies [0.03%]
免疫组化法评估DNA错配修复蛋白状态的评价方案及两种抗体的选择建议
Leonardo Saul Lino-Silva,Ángeles Galán-Ramírez,Sabrina B Martínez-Villavicencio et al.
Leonardo Saul Lino-Silva et al.
Determining the status of DNA mismatch repair (MMR) proteins is crucial for patients because they may respond differently to specific treatments and have a better prognosis. We proposed a panel with only 2 antibodies to determine the status...
On interactions between fever, inflammation, and the autonomic nervous system [0.03%]
关于发热、炎症与自主神经系统的相互作用
Beato Suwa
Beato Suwa
The pathologist Simon Samuel, one of the pioneers in the field of the autonomic nervous system during the 19 th century, contributed significantly to the understanding of the pathological mechanisms underlying inflammation. The remarkable a...
Investigation of clinicopathological and prognostic association of TERT promoter mutation in non-small cell lung cancer in a Turkish population [0.03%]
土耳其人群非小细胞肺癌中TERT启动子突变的临床病理及预后相关性研究
Onur Dülger,Ilhan Yaylim,Ismail Yilmaz et al.
Onur Dülger et al.
Non-small cell lung cancer (NSCLC) is characterized by a complex and heterogeneous molecular basis. Telomerase reverse transcriptase ( TERT ) gene promoter mutations have been implicated in various cancer types. We aimed to investigate the ...
Crosstalk between OPG/RANKL/RANK in bone marrow mesenchymal stem cells and Wnt/b-catenin pathway in prostate cancer cells regulates bone metastasis of prostate cancer [0.03%]
骨髓间充质干细胞中的OPG/RANKL/RANK与前列腺癌细胞中Wnt/β-连环蛋白信号通路的串扰调控前列腺癌骨转移
Shihua Ye,Qiongyun Lin,Meihua Deng et al.
Shihua Ye et al.
This study aimed to investigate whether the crosstalk between the osteoprotegerin (OPG)/receptor activator of nuclear factor-kB (RANK)/receptor activator of nuclear factor-kB ligand (RANKL) in bone marrow mesenchymal stem cells (BMSCs) and ...