Hardware and quality-control factors influencing digital pathology reproducibility [0.03%]
影响数字病理学再现性的硬件和质量控制因素
Yan Li,Tiantian Li
Yan Li
Digital pathology (DP) converts glass slides into whole-slide images (WSI), enabling quantitative and remote diagnostics. This systematized review examines how hardware and instrumentation (HI) form the technical basis for reliable DP. Evid...
Correct answer to the quiz. Check your diagnosis Cellular dermatofibroma [0.03%]
测验的正确答案。检查您的诊断结果：细胞海绵状血管瘤皮肤纤维瘤
Magdalena Justyna Kacperska-Olborska,Bogusław Olborski,Jerzy Ogłuszka
Magdalena Justyna Kacperska-Olborska
Dermatofibroma (DF), also known as fibrous histiocytoma, is one of the most common cutaneous soft-tissue lesions, accounting for approximately 3% of skin lesion specimens received by dermatopathology laboratories. Dermatofibroma is a benign...
Spontaneous pathological splenic rupture as a first manifestation of mantle cell lymphoma - a case report and literature review [0.03%]
自发性脾病理性破裂作为套细胞淋巴瘤的首发表现一例报告及文献复习
Antoni Knera,Wojciech Ciesielski,Adam Placek et al.
Antoni Knera et al.
Splenic rupture is a critical surgical condition that poses an immediate threat to the patient's life. In most cases, mechanical trauma to the organ results in the rupture of the capsule, leading to hemorrhage into the peritoneal cavity. Sp...
Joško Beziæ,Toni Čeprnja
Joško Beziæ
Invasive breast papillary carcinoma is a rare type of breast cancer histologically characterized by infiltrative papillary growth without visible surrounding fibrous capsule. Here, we report the case of an invasive papillary carcinoma in wh...
TROP-2 expression in triple-negative and human epidermal growth factor receptor 2 enriched breast cancers and its relationship with clinicopathologic parameters [0.03%]
TROP-2在三阴性及富含人表皮生长因子受体2型乳腺癌中的表达及其与临床病理参数的关系
Hale Kivrak,Duygu Simsek,Egemen Akincioglu et al.
Hale Kivrak et al.
TROP-2 is a transmembrane calcium signaling molecule that is detected at a high rate (63%) in breast cancers. There are conflicting data on its relationship with subtypes, clinical, and pathological data in breast cancer. TROP-2 expression ...
Unravelling the link between mismatch repair protein deficiency and immune checkpoint markers - programmed death ligand 1 and galectin-9 expression in malignant melanoma [0.03%]
Mismatch修复蛋白缺陷与免疫检查点分子pd-l1和gal-9在恶性黑色素瘤中的表达相关性研究
Gizem Teoman,Mustafa Emre Ercin,Safak Ersoz et al.
Gizem Teoman et al.
Malignant melanoma is an aggressive skin cancer, with immune evasion mechanisms contributing to tumour progression. This study evaluated the relationship between mismatch repair (MMR) protein loss and the expression of immune checkpoint mol...
A retrospective analysis of secondary malignancy development in nevus sebaceus [0.03%]
关于脂溢性角化病样丘疹发病的回顾分析
Fatma Seher Pehlivan,Ömer Atmış,Hanife Seda Mavili et al.
Fatma Seher Pehlivan et al.
Nevus sebaceous (NS) is a benign hamartomatous lesion; however, benign proliferative lesions are less frequently associated with secondary neoplasms. The aim of this study is to evaluate the prevalence of secondary benign and malignant tumo...
MiR-21-5p regulates colon adenocarcinoma cell progression and epithelial-mesenchymal transition by negatively regulating Tensin 1 [0.03%]
微RNA-21-5p通过抑制张力蛋白1的表达调控结肠腺癌细胞进展及上皮间质转化作用机制研究
Lingqing Cai,Jiangrong Chen,Chuanqing Ke et al.
Lingqing Cai et al.
Colon adenocarcinoma (COAD) is one of the most prevalent forms of cancer in the world. Still, the molecular mechanism of COAD development remains unknown, making it especially important to investigate the molecular mechanism of COAD develop...
Molecular profiling of sporadic medullary thyroid carcinomas - a next-generation sequencing-based study [0.03%]
基于下一代测序的散发性甲状腺髓样癌分子分型研究
Serdar Altinay,Altan Kara,Mustafa Gülbağcı et al.
Serdar Altinay et al.
Medullary thyroid carcinomas (MTCs) are 75% sporadic and 25% hereditary. This study aimed to determine the histopathological parameters and molecular changes of sporadic MTCs in a university hospital by targeted next-generation sequencing (...
Clinicopathological features of anaplastic lymphoma kinase-rearranged lung adenocarcinoma initially misdiagnosed with invasive mucinous adenocarcinoma - a retrospective study [0.03%]
肉芽肿型肺腺癌误诊为浸润性黏液腺癌的临床病理特征回顾性研究
Xiaomin Dai,Xiaoyue Feng,Yanbo Lu et al.
Xiaomin Dai et al.
Anaplastic lymphoma kinase (ALK) rearranged lung adenocarcinoma is frequently characterised by prominent mucin secretion and a heterogeneous population of mucinous cells. These histological features may result in misdiagnosis as invasive mu...