Origin of dedifferentiated adipocyte-derived cells (DFAT) during ceiling culture in an Adiponectin Cre-Recombinase mouse model [0.03%]
顶叶培养过程中脂库创伤病灶中DED分化而来细胞（DFAT）起源的单细胞测序分析：Adiponectin-Cre小鼠模型中的证据
Marie-Frédérique Gauthier,Giada Ostinelli,Mélissa Pelletier et al.
Marie-Frédérique Gauthier et al.
DFAT cells represent an attractive source of stem cells in tissue engineering and in the potential treatment of several clinical conditions. Our objective was to determine whether DFAT cells originate from mature adipocytes and address whet...
Fusarium graminearum Ste2 and Ste3 receptors undergo peroxidase-induced heterodimerization when expressed heterologously in Saccharomyces cerevisiae [0.03%]
当异源表达于酿酒酵母中时，Fusarium graminearum 的Ste2和Ste3受体经历过氧化物酶诱导的异二聚化
Tanya Sharma,Robert Y Jomphe,Dongling Zhang et al.
Tanya Sharma et al.
Fusarium graminearum FgSte2 and FgSte3 are G-protein-coupled receptors (GPCRs) shown to play roles in hyphal chemotropism and fungal plant pathogenesis in response to activity arising from host-secreted peroxidases. Here, we follow up on th...
Antibiofilm activities of lactoferricin-related Trp- and Arg-rich antimicrobial hexapeptides against pathogenic Staphylococcus aureus and Pseudomonas aeruginosa strains [0.03%]
几种抗菌六肽类乳铁氨基末端片段的抗绿脓杆菌和金黄色葡萄球菌生物被膜活性
Gopal Ramamourthy,Hans J Vogel
Gopal Ramamourthy
Recently, several antimicrobial peptides (AMPs), varying in length from 12 to 37 residues, have been shown to act as antibiofilm agents. Here, we report a study of 23 hexapeptides modeled after four different Trp- and Arg-rich AMPs, includi...
Treatment of lactoferrin and antimicrobial peptide N6 on bacterial enteritis caused by Escherichia coli in mice [0.03%]
乳铁蛋白和抗菌肽N6治疗鼠致病性大肠杆菌感染的研究
Xuanxuan Ma,Kun Zhang,Na Yang et al.
Xuanxuan Ma et al.
Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in humans and animals. The study aimed to evaluate the efficacy of bovine lactoferrin (bLf) as an adjuvant combined with AMP (N6) in the treatment of E. coli-induced bacte...
Lactoferrin modulates oxidative stress and inflammatory cytokines in a murine model of dysbiosis induced by clindamycin [0.03%]
乳铁蛋白通过调节小鼠克林霉素诱导的菌群失调模型中的氧化应激和炎症因子起治疗作用
Inés Abad,Andrea Bellés,Ana Rodríguez-Largo et al.
Inés Abad et al.
Antibiotics, specifically clindamycin (Clin), cause intestinal dysbiosis, reducing the microbiota with anti-inflammatory properties. Furthermore, Clin can induce alterations in the immune responses and oxidative stress. Lactoferrin, among o...
Neuroprotective effects of whey and buttermilk-based formulas on a DSS-induced colitis murine model [0.03%]
一种新的结肠炎小鼠模型的神经保护效应的研究：以乳清和发酵乳为基础的配方奶粉的研究
Berta Buey,Eva Latorre,Marta Castro et al.
Berta Buey et al.
Inflammatory bowel disease is a gut-brain axis disorder that comprises chronic inflammatory conditions affecting the gastrointestinal tract, where alterations in the mood of patients are common. Gut-brain axis is a bidirectional communicati...
Canada's contributions to RNA research: past, present, and future perspectives [0.03%]
加拿大在RNA研究上的贡献：过去、现在和未来展望
Eric Lécuyer,Martin Sauvageau,Ute Kothe et al.
Eric Lécuyer et al.
The field of RNA research has provided profound insights into the basic mechanisms modulating the function and adaption of biological systems. RNA has also been at the center stage in the development of transformative biotechnological and m...
Structure and Function of Fermentation-Derived Bovine Lactoferrin Produced from Komagataella phaffii [0.03%]
假丝酿酒酵母发酵生产的乳铁蛋白的结构和功能研究
Emma Skoog,Vanessa Feher Castagna,Shafraz Omer et al.
Emma Skoog et al.
Bovine lactoferrin (bLf) confers significant functional benefits for human health, but low concentrations in milk and high cost of commercial production limit availability and thus product application. Precision fermentation offers a soluti...
Neurodevelopmental functions and activities of the KAT3 class of lysine acetyltransferases [0.03%]
赖氨酸乙酰化酶3类（KAT3）的神经发育功能和作用机制研究
Ashraf K Shahib,Mojgan Rastegar,Andre J van Wijnen et al.
Ashraf K Shahib et al.
The human lysine acetyltransferases KAT3A (CREBBP) and KAT3B (EP300) are essential enzymes in gene regulation in the nucleus. Their ubiquitous expression in metazoan cell types controls cell proliferation and differentiation during developm...
Bovine lactoferrin and chimera lactoferrin prevent and destroy Salmonella Typhimurium biofilms in Caco-2 cells [0.03%]
牛乳铁蛋白和嵌合乳铁蛋白可预防和破坏Caco-2细胞中的伤寒沙门氏菌生物膜
Laura E Quintero-Martínez,Adrián Canizalez-Román,Uriel A Angulo-Zamudio et al.
Laura E Quintero-Martínez et al.
Salmonellosis is a common foodborne disease caused by Salmonella bacteria. The emergence of multidrug-resistant (MDR) Salmonella serotypes, such as Typhimurium, and Salmonella's ability to form biofilms contribute to their resistance and pe...