Focus on aging, heart failure, regeneration, and cardiovascular medicine [0.03%]
聚焦心脏衰老、心力衰竭、修复与再生及心血管医学
Srinivas M Tipparaju,Ravikumar Manickam,Guilherme H Oliveira et al.
Srinivas M Tipparaju et al.
The Guest Editors provide highlights and overview of the eCollection which was based on the International Academy of Cardiovascular Sciences-North American Section (IACS-NAS) 2023 annual meeting. The overall impact generated by the papers p...
Insulin modulates MMP-2 and 9 activities through the control of oxidative stress in the heart of diabetic rats Running title: Insulin modulates MMPs via oxidative stress control [0.03%]
胰岛素通过控制氧化应激调节糖尿病大鼠心脏中基质金属蛋白酶-2和-9的活性
Bruno Teixeira Martins,Isabela Jesus de Deus,Vitor Valadares Gutierres et al.
Bruno Teixeira Martins et al.
This study aimed to evaluate the effects of insulin therapy on oxidative stress markers, matrix metalloproteinases (MMPs) 2 and 9 activities and cardiac remodeling in alloxan-induced diabetic rats. Forty-two male Wistar rats were randomly a...
Finding a Link Between the TRPV4 Ion Channel and Angiogenesis: A Potential Therapeutic Target for Vascular Remodeling [0.03%]
TRPV4离子通道与血管生成之间的联系：血管重塑治疗靶点的潜在候选者
Gabriel Malka,Vanessa Salucci,Andreas Bergdahl
Gabriel Malka
Angiogenesis, the formation of new blood vessels, is crucial in ischemic heart disease to improve blood supply to the heart. Meanwhile, in cancer, inhibiting angiogenesis can limit tumor growth by reducing oxygen and nutrients. Calcium ions...
In memoriam: Morley D. Hollenberg (1944-2025), scientist, artist, mentor, and friend [0.03%]
缅怀莫尔利·霍伦伯格（1944-2025）：科学家、艺术家、导师和朋友
Rithwik Ramachandran
Rithwik Ramachandran
Lysine acetylation of aquaporin-3 does not improve lithium-induced nephrogenic diabetes insipidus [0.03%]
精氨酸加压素非肽类受体激动剂研究进展及未来方向
Nha V Huynh,Hung Nguyen,Kelly A Hyndman
Nha V Huynh
Aquaporin-3 (AQP3) is expressed in the basolateral membrane of the renal principal cell contributing to vasopressin-mediated water reabsorption and urine concentration. We reported that post-translational acetylation of lysine 282 of AQP3 p...
Aerobic and/or Resistance Exercise in Restoring Metabolic Dysregulation Induced by Chronic Sleep Restriction in Rats [0.03%]
有氧运动和/或抗阻训练改善慢性睡眠限制大鼠代谢紊乱的研究
Gülhan Cansu Şen,Muhammed Ali Aydın,Ozan Öner et al.
Gülhan Cansu Şen et al.
Chronic sleep restriction disrupts blood glucose regulation, leading to glucose intolerance and insulin resistance. Regular exercises, however, are known to enhance glycemic control. This study aimed to evaluate the regulatory effects of th...
Effects of vitamin B6 on cardiometabolic biomarkers, cardiac oxidative stress and enzymes activities, and cardiovascular histomorphometric parameters in hyperhomocysteinemic rats [0.03%]
维生素B6对高同型半胱氨酸血症大鼠心血管生化、氧化应激和心脏组织学参数的影响
Dušan Todorović,Marija Stojanović,Jovana Jakovljević Uzelac et al.
Dušan Todorović et al.
Hyperhomocysteinemia can induce significant alterations in the cardiovascular system, and vitamin B6 is one of the primary cofactors of enzymes involved in homocysteine metabolism. The aim of this study was to examine the effects of vitamin...
Suppression of protein kinase RNA-like endoplasmic reticulum kinase by probiotics circumvents cardiovascular risk profile in experimentally induced PCOS model [0.03%]
益生菌通过抑制实验性多囊卵巢综合征模型中的蛋白激酶R样内质网激酶来规避心血管风险指标
Stephanie Esosa Areloegbe,Linus Anderson Enye,Kehinde S Olaniyi
Stephanie Esosa Areloegbe
The present study was designed to investigate the role of PERK in CVD risk associated with polycystic ovarian syndrome (PCOS) in experimental rat model, and the therapeutic benefits of probiotics. Eight-weeks-old female Wistar rats were ass...