Atorvastatin can ameliorate left atrial stunning induced by radiofrequency ablation for atrial fibrillation [0.03%]
阿托伐他汀能改善射频消融治疗房颤后的左心房顿抑症状
Ruiqin Xie,Yingtao Yang,Wei Cui et al.
Ruiqin Xie et al.
The objective of this study was to study the functional changes of the left atrium after radiofrequency ablation treatment for atrial fibrillation and the therapeutic effect of atorvastatin. Fifty-eight patients undergoing radiofrequency ab...
Mozhgan Ghobadi Pour,Naser Mirazi,Hojjatollah Alaei et al.
Mozhgan Ghobadi Pour et al.
Silymarin, a mixture of antihepatotoxic flavonolignans used in the treatment of liver diseases, and lactulose, a nonabsorbable synthetic disaccharide, were investigated to analyze their probable synergic and healing effects in a hepatic cir...
Characterization of the role of endogenous nitric oxide in myogenic vascular oscillations during cooling-evoked hemodynamic perturbations of rats [0.03%]
内源性一氧化氮在冷却诱发的大鼠血管动力学扰动期间的肌源性振荡中的作用机制研究
Yi-Hsien Lin,Yia-Ping Liu,Yu-Chieh Lin et al.
Yi-Hsien Lin et al.
Rapid immersion of a rat's limbs into 4 °C water, a model of cold stress, can elicit hemodynamic perturbations (CEHP). We previously reported that CEHP is highly relevant to sympathetic activation and nitric oxide production. This study id...
Danah Al Hattab,Michael P Czubryt
Danah Al Hattab
Cardiac fibrosis is a significant global health problem that is closely associated with multiple forms of cardiovascular disease, including myocardial infarction, dilated cardiomyopathy, and diabetes. Fibrosis increases myocardial wall stif...
Yan Lu,Hope D Anderson
Yan Lu
Cannabis sativa has long been used for medicinal purposes. To improve safety and efficacy, compounds from C. sativa were purified or synthesized and named under an umbrella group as cannabinoids. Currently, several cannabinoids may be presc...
Anti-inflammatory and neuroprotective activity of boswellic acids in rotenone parkinsonian rats [0.03%]
乳香酸抗炎和神经保护作用的罗tenone帕金森病大鼠中的研究
Angie M Ameen,Amany Y Elkazaz,Hala M F Mohammad et al.
Angie M Ameen et al.
There is evidence that inflammation and oxidative stress contribute to the neurodegenerative changes observed in Parkinson's disease. Unfortunately, there is a lack of curative treatment for this debilitating movement disorder. Boswellic ac...
Primary human monocytes differentiate into M2 macrophages and involve Notch-1 pathway [0.03%]
原人单核细胞向M2型巨噬细胞分化与Notch-1信号通路的关系
Dinender K Singla,Jing Wang,Reetu Singla
Dinender K Singla
The current study investigates whether inhibiting the Notch-1 signaling pathway in primary human monocytes enhances M2 macrophage differentiation. We generated a primary human monocyte cell culture model to understand the effect of the Notc...
Effects of trimetazidine on interleukin-2 and interleukin-8 concentrations in patients with coronary artery disease [0.03%]
曲美他嗪对冠心病患者血清中白介素-2和白介素-8浓度的影响
Aleksander Danikiewicz,Janusz Szkodziński,Bartosz Hudzik et al.
Aleksander Danikiewicz et al.
Trimetazidine (TMZ) exhibits metabolic and cardioprotective effects. The aim of this study was to assess the effects of TMZ on interleukin-2 (IL-2) and interleukin-8 (IL-8) serum concentrations in 156 patients with stable coronary artery di...
Long-acting PDE5 inhibitor tadalafil prevents early doxorubicin-induced left ventricle diastolic dysfunction in juvenile mice: potential role of cytoskeletal proteins [0.03%]
长效PDE5抑制剂坦洛新预防左旋多巴诱发的幼年小鼠心室舒张功能障碍：细胞骨架蛋白的潜在作用
Mohamed Nagiub,Scott Filippone,David Durrant et al.
Mohamed Nagiub et al.
The chemotherapeutic use of doxorubicin (Dox) is hindered due to the development of irreversible cardiotoxicity. Specifically, childhood cancer survivors are at greater risk of Dox-induced cardiovascular complications. Because of the potent...
Myocardial homing of mesenchymal stem cells following intrapericardial application and amplification by inflammation - an experimental pilot study [0.03%]
心内膜应用和炎症放大的间充质干细胞的心肌定位-一项实验性研究
Nina Jung,Heinz Rupp,A Rembert Koczulla et al.
Nina Jung et al.
Recent studies demonstrated potential effects of stem cells on cardiac function in heart failure. However, influences of the technique of application remained undetermined. In the present study, the pericardial sac was used as depot for flu...