Neurogenic bowel dysfunction in patients with multiple sclerosis: prevalence, impact, and management strategies [0.03%]
多发性硬化患者的神经源性肠道功能障碍：患病率、影响及管理策略
Giuseppe Preziosi,Ayeshah Gordon-Dixon,Anton Emmanuel
Giuseppe Preziosi
Bowel dysfunction in patients with multiple sclerosis (MS) is highly prevalent. Constipation and fecal incontinence can coexist and alternate, impacting on the patient's quality of life and social interactions, as well as burdening the care...
Efficacy of stem cell therapy in ambulatory and nonambulatory children with Duchenne muscular dystrophy - Phase I-II [0.03%]
干细胞治疗杜氏肌营养不良门诊和非门诊儿童的疗效：I-II期临床试验
Alper Dai,Osman Baspinar,Ahmet Yeşilyurt et al.
Alper Dai et al.
Purpose: Duchenne muscular dystrophy (DMD) is an X-linked recessive pediatric disorder that ultimately leads to progressive muscle degeneration. It has been known that cell-based therapies were used to promote muscle rege...
Continuous noninvasive ventilation for respiratory failure in patients with amyotrophic lateral sclerosis: current perspectives [0.03%]
肌萎缩侧索硬化患者呼吸衰竭的持续性非侵入性通气：当前观点
Giuseppe Fiorentino,Anna Annunziata,Anna Michela Gaeta et al.
Giuseppe Fiorentino et al.
Respiratory failure is a recognized late complication of amyotrophic lateral sclerosis. It is related to the neurological progression of the diseases with the impairment of the respiratory musculature. Survival and quality of life of amyotr...
Cladribine tablets' potential role as a key example of selective immune reconstitution therapy in multiple sclerosis [0.03%]
克拉利din片作为选择性免疫重建疗法治疗多发性硬化症的关键范例的潜力
Alexey N Boyko,Olga V Boyko
Alexey N Boyko
Multiple sclerosis (MS) is one of the most important, disabling, and prevalent neurological disorders of young adults. It is a chronic inflammatory and neurodegenerative disease when autoreactive B and T cells have downstream effects that r...
Luca Prosperini,Letizia Castelli
Luca Prosperini
Multiple sclerosis (MS) is a disease that heavily affects postural control, predisposing patients to accidental falls and fall-related injuries, with a relevant burden on their families, health care systems and themselves. Clinical scales a...
Employment of patients with multiple sclerosis: the influence of psychosocial-structural coping and context [0.03%]
多发性硬化患者的就业情况：心理社会结构性应对机制和环境因素的影响
Lavanya Vijayasingham,Fatima Fanna Mairami
Lavanya Vijayasingham
Patients with multiple sclerosis tend to report higher levels of work difficulties and negative outcomes, such as voluntary and involuntary work termination and reduced work participation. In this article, we discuss the complex interaction...
Cristina Al-Khalili Szigyarto,Pietro Spitali
Cristina Al-Khalili Szigyarto
Numerous biomarkers have been unveiled in the rapidly evolving biomarker discovery field, with an aim to improve the clinical management of disorders. In rare diseases, such as Duchenne muscular dystrophy, this endeavor has created a wealth...
Anjana Sadanand,Anjali Janardhanan,Arun Sankaradoss et al.
Anjana Sadanand et al.
Neurodegenerative diseases have many similar pathological conditions, and very few studies exist which detail their molecular features. Proteins like Na+/K+-ATPase (NKA), α-spectrin (SPTA) and drebrin have been reported to be involved in t...
Leslie Sedal,Antony Winkel,Joshua Laing et al.
Leslie Sedal et al.
Over the past 20 years, the available therapies for multiple sclerosis have expanded exponentially. With several more agents likely to be approved for public funding in Australia in the next 12 months on top of the existing multitude of Aus...