Zanubrutinib in Mantle Cell Lymphoma Management: A Comprehensive Review [0.03%]
赞布鲁替尼在套细胞淋巴瘤治疗中的应用：全面回顾
Nada Alsuhebany,Congshan Pan,Eileen Holovac et al.
Nada Alsuhebany et al.
Purpose: The pharmacology, pharmacokinetics, pharmacodynamics, clinical efficacy, and safety of zanbrutinib are described. Summary: Man...
90Yttrium Ibritumomab Tiuxetan (Zevalin) for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Report of 5 Cases [0.03%]
钇[90Y]依替妥珠单抗治疗慢性淋巴细胞白血病/小淋巴细胞淋巴瘤5例报告
Jing Wang,Firas Baidoun,Han W Tun et al.
Jing Wang et al.
Radioimmunotherapy (RIT) with radio-labeled monoclonal antibodies to CD20 produces a high response rate in patients with low-grade B-cell lymphomas. The use of this modality in patients with chronic lymphocytic leukemia (CLL) has been spora...
Differential Diagnosis and Therapeutic Advances in Multiple Myeloma: A Review Article [0.03%]
浆细胞瘤的鉴别诊断与治疗进展：综述文章
Munawwar Hussain,Sarvari Yellapragada,Samer Al Hadidi
Munawwar Hussain
Multiple myeloma (MM) is a hematologic malignancy characterized by the abnormal clonal proliferation of plasma cells that may result in focal bone lesions, renal failure, anemia, and/or hypercalcemia. Recently, the diagnosis and treatment o...
Successful Anatomy Adapted Therapeutic Management and Genetic Profiling of Primary Pituitary Diffuse Large B-Cell Lymphoma [0.03%]
原发垂体弥漫大B细胞淋巴瘤的治疗适应解剖学和基因特征谱分析成功经验总结
ErinMarie O Kimbrough,Vivek Gupta,Liuyan Jiang et al.
ErinMarie O Kimbrough et al.
Primary pituitary diffuse large B-cell lymphoma (PPL) has been regarded as a subtype of primary central nervous system lymphoma (PCNSL); however, the pituitary gland is located outside the blood brain barrier (BBB) with neural and vascular ...
Tesfaye Gessese,Fikir Asrie,Zewudu Mulatie
Tesfaye Gessese
Human immunodeficiency virus infection is related with an increased risk of hematological malignancy principally, non-Hodgkin lymphoma. Most non-Hodgkin lymphomas are acquired immunodeficiency syndrome defining and constitute greater than 5...
Naji Bou Zeid,Victor Yazbeck
Naji Bou Zeid
Phosphatidylinositol 3-kinases (PI3Ks) are a family of intracellular signal transducer enzymes that can attach a phosphate group to the 3'-hydroxyl of the inositol moiety of membrane-embedded phosphatidylinositol (PI). PI3Ks have been shown...
FLT3 Inhibitors as Maintenance Therapy after Allogeneic Stem-Cell Transplantation [0.03%]
异基因干细胞移植后 FLT3 抑制剂作为维持治疗
Amanda Blackmon,Ibrahim Aldoss,Brian J Ball
Amanda Blackmon
Mutations in the FLT3 gene are associated with poor prognosis in patients with AML, even after consolidation with allogeneic hematopoietic cell transplantation (alloHCT) in first remission. Treatment failure in FLT3-mutated AML is largely d...
CAR T-Cell Therapy for Patients with Multiple Myeloma: Current Evidence and Challenges [0.03%]
多发性骨髓瘤CAR-T细胞疗法现状及挑战
Matthew J Rendo,Jacinth J Joseph,Liem Minh Phan et al.
Matthew J Rendo et al.
The therapeutic landscape of multiple myeloma (MM) has benefited from an emergence of novel therapies over the last decade. By inducing T-cell kill of target cancer cells, chimeric antigen receptor (CAR) T-cell therapies have improved outco...
Differential Diagnosis of Waldenström's Macroglobulinemia and Early Management: Perspectives from Clinical Practice [0.03%]
Waldenström巨球蛋白血症的鉴别诊断及早期处理：临床实践观点
Shashank Cingam,Surbhi Sidana
Shashank Cingam
Waldenström's Macroglobulinemia (WM) is a clonal B-lymphocyte neoplasm characterized by the presence of IgM monoclonal protein and ≥10% bone marrow involvement with lymphoplasmacytic cells. Several mature B-cell and plasma cell disorders ...
A Promising Future for Precision Epigenetic Therapy for Follicular and Diffuse Large B-Cell Lymphoma? [0.03%]
精确表观遗传治疗滤泡性和弥漫性大B细胞淋巴瘤的前景如何？
Clement Chung
Clement Chung
Epigenetic mechanisms such as DNA hypermethylation or histone deacetylation normally silence gene expression that regulates numerous cellular activities. Germinal center-derived lymphomas such as follicular lymphoma (FL) and diffuse large B...