The Antibody Drug Conjugate, Belantamab-Mafodotin, in the Treatment of Multiple Myeloma: A Comprehensive Review [0.03%]
Belantamab-mafodotin治疗多发性骨髓瘤的疗效和安全性：综述分析
Adrian Alfonso Almodovar Diaz,Samhar Samer Alouch,Yogesh Chawla et al.
Adrian Alfonso Almodovar Diaz et al.
Despite recent advancements in treatments, including proteasome inhibitors, immunomodulators, and anti-CD38 monoclonal antibodies, multiple myeloma (MM) remains mostly incurable with patients frequently experiencing disease relapses due to ...
Highly Curative Treatment of High-Risk Acute Promyelocytic Leukemia: Induction and Consolidation with ATRA+ATO+anthracyclines and Maintenance with ATRA+RIF [0.03%]
高危急性早幼粒细胞白血病高治愈率的诱导及consolidation方案：ATRA+ATO+蒽环类，维持治疗期为ATRA+RIF
Dan Liu,Juan Tong,Erling Chen et al.
Dan Liu et al.
Background: The aim of the study was to evaluate the efficacy and safety of induction and consolidation with all-trans retinoic acid (ATRA) +arsenic trioxide (ATO) +anthracyclines and maintenance with ATRA +Realgar-Indigo...
Albumin-to-Globulin Ratio Combined with Neutrophil-to-Lymphocyte Ratio as a Prognostic Predictor in Multiple Myeloma with Renal Impairment [0.03%]
肾损害患者的多发性骨髓瘤中，白蛋白与球蛋白比值联合中性粒细胞与淋巴细胞比值的预后预测作用
Yingzi Zhang,Xiajuan Yao,Yaoquan Zhang et al.
Yingzi Zhang et al.
Background: The albumin-to-globulin ratio (AGR) and neutrophil-to-lymphocyte ratio (NLR) have been recently regarded as promising prognostic factors in various malignancies. The present study investigated the prognostic v...
Identification of a Prognostic Model Based on NK Cell-Related Genes in Multiple Myeloma Using Single-Cell and Transcriptomic Data Analysis [0.03%]
基于单细胞和转录组数据分析识别多发性骨髓瘤中与NK细胞相关基因的预后模型
Nan Mei,Sha Gong,Lizhao Wang et al.
Nan Mei et al.
Background: Multiple myeloma (MM), an incurable plasma cell malignancy. The significance of the relationship between natural killer (NK) cell-related genes and clinical factors in MM remains unclear. ...
AC024896.1/miR-363-3p Axis Regulates the Malignant Progression of Acute Myeloid Leukemia by Cuproptosis-Related Gene MYO1B [0.03%]
AC024896.1/miR-363-3p轴通过铜死亡相关基因MYO1B调控急性髓系白血病恶性进展
Jie Zhang,Yuhuan Zheng,Hongjuan Liu et al.
Jie Zhang et al.
Background: Acute myeloid leukemia (AML) is a hematological malignancy with poor patient prognosis. Cuprotosis is a newly discovered cell death that regulates the proliferation and progression of tumor cells. Long non-cod...
Francesco Malfona,Anna Maria Testi,Sabina Chiaretti et al.
Francesco Malfona et al.
Despite excellent results in frontline therapy, particularly in pediatric age, refractory Burkitt lymphoma still remains a therapeutic challenge, with dismal outcome. The prognosis is very poor, ranging from less than 10% to 30-40%, with lo...
Andrea Duminuco,Patrick Harrington,Claire Harrison et al.
Andrea Duminuco et al.
Polycythemia vera (PV) is a subtype of myeloproliferative neoplasms characterized by impaired quality of life and severe complications. Despite the increasingly in-depth knowledge of this condition, it necessitates a multifaceted management...
Zanubrutinib in Mantle Cell Lymphoma Management: A Comprehensive Review [0.03%]
赞布鲁替尼在套细胞淋巴瘤治疗中的应用：全面回顾
Nada Alsuhebany,Congshan Pan,Eileen Holovac et al.
Nada Alsuhebany et al.
Purpose: The pharmacology, pharmacokinetics, pharmacodynamics, clinical efficacy, and safety of zanbrutinib are described. Summary: Man...
90Yttrium Ibritumomab Tiuxetan (Zevalin) for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Report of 5 Cases [0.03%]
钇[90Y]依替妥珠单抗治疗慢性淋巴细胞白血病/小淋巴细胞淋巴瘤5例报告
Jing Wang,Firas Baidoun,Han W Tun et al.
Jing Wang et al.
Radioimmunotherapy (RIT) with radio-labeled monoclonal antibodies to CD20 produces a high response rate in patients with low-grade B-cell lymphomas. The use of this modality in patients with chronic lymphocytic leukemia (CLL) has been spora...
Differential Diagnosis and Therapeutic Advances in Multiple Myeloma: A Review Article [0.03%]
浆细胞瘤的鉴别诊断与治疗进展：综述文章
Munawwar Hussain,Sarvari Yellapragada,Samer Al Hadidi
Munawwar Hussain
Multiple myeloma (MM) is a hematologic malignancy characterized by the abnormal clonal proliferation of plasma cells that may result in focal bone lesions, renal failure, anemia, and/or hypercalcemia. Recently, the diagnosis and treatment o...