Venetoclax Plus Hypomethylating Agents for Treatment-Naïve Myelodysplastic Syndromes with Increased Blasts: A Prospective Multicenter Cohort Study [0.03%]
用于治疗初治的伴高比例原始细胞骨髓增生异常综合征患者的维奈克拉联合低甲基化药物方案：一项前瞻性多中心队列研究
Na Zhao,Lijun Zhu,Xing Hu et al.
Na Zhao et al.
Purpose: Evidence supporting venetoclax combined with hypomethylating agents (HMAs) in treatment-naïve myelodysplastic syndromes with increased blasts (MDS-IB), a biologically aggressive subset with high risk of leukemic...
Prognostic Value of the Aggregate Inflammation Systemic Index (AISI) in Patients with Diffuse Large B-Cell Lymphoma: A Multicenter Retrospective Study [0.03%]
炎症整体指数(AISI)在弥漫大B细胞淋巴瘤患者中的预后价值：多中心回顾性研究
Xicheng Chen,Linyu Huang,Qiming Zhang et al.
Xicheng Chen et al.
Background: The aggregate index of systemic inflammation (AISI, calculated as neutrophil count × monocyte count × platelet count/lymphocyte count) reflects systemic inflammatory status; however, its prognostic role in d...
Study on the Role of Neutrophil Extracellular Traps-Based Risk Model and Discriminative Gene LTF in the Prognosis of Acute Myeloid Leukemia and the Regulation of Immune Microenvironment [0.03%]
关于中性粒细胞胞外陷阱基风险模型及分化基因LTF在急性髓系白血病预后中的作用及对免疫微环境调节的研究
Yongjian Li,Jingru Zhang,Tingting Liu et al.
Yongjian Li et al.
Introduction: Dysregulation of neutrophil extracellular traps (NETs) formation is implicated in cancer progression, coagulation, and metastasis; however, the association with acute myeloid leukemia (AML) prognosis and the...
Crosstalk Between FOXN3 and E2F5 Reveals a Novel Tumor Suppressive Pathway in Acute Myeloid Leukemia via MAPK Signaling: Implications for Potential Future Targeted Therapy [0.03%]
FOXN3与E2F5的串扰通过MAPK信号转导揭示急性髓系白血病中的一种新型抑癌通路：对未来潜在靶向治疗的意义
Jinjing Zhang,Qiao Jiang,Tong Liu et al.
Jinjing Zhang et al.
Objective: To investigate the mechanism of FOXN3 in acute leukemia. Methods: ChIP-seq experiments were performed using FOXN3-specific a...
Safety and Efficacy of Flumatinib in Patients with Chronic Phase Chronic Myeloid Leukemia: A Real-Life Cohort Observational Study [0.03%]
氟马替尼治疗慢性期慢性髓性白血病患者的真实世界队列观察研究
Fang Cheng,Zheng Cui,Qiang Li et al.
Fang Cheng et al.
Background: This study aims to comprehensively evaluate the safety and effectiveness of flumatinib in both first-line and subsequent-line therapies in 244 chronic-phase chronic myeloid leukemia (CML-CP) patients. ...
Natural Killer/T-Cell Lymphoma-Associated Hemophagocytic lymphohistiocytosis-a Rare and Dangerous Disease [0.03%]
与自然杀伤T细胞淋巴瘤相关的噬血细胞性淋巴组织细胞增生症——一种罕见且危险的疾病
Guangqiang Meng,Manzhi Wang,Congcong Sun et al.
Guangqiang Meng et al.
Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome characterised by the reactive activation of cytotoxic T-lymphocytes and macrophages along with a substantial amount of cytokine secretion caused by various inductions. Natural ...
Construction and Validation of an N7-Methylguanosine-Related Prognostic Model for Acute Myeloid Leukemia [0.03%]
急性髓系白血病中N7-甲基鸟苷相关预后模型的构建与验证
Lina Wang,Ming Li,Yaming Xi
Lina Wang
Purpose: Increasing evidence suggests the involvement of N7-methylguanosine (m7G) in cancer biology. However, its role in acute myeloid leukemia (AML) remains unclear. Herein, bioinformatics approaches were used to obtain...
Health Disparities in Acute Myeloid Leukemia Patients Undergoing Treatment with Tyrosine Kinase Inhibitor (TKI) Therapy Targeting FLT3, IDH1, or IDH2 [0.03%]
FLT3、IDH1或IDH2酪氨酸激酶抑制剂(TKI)治疗急性髓系白血病患者的健康差异性
Manuel R Espinoza-Gutarra,Brooke A Jarrett,Xiaoliang Wang et al.
Manuel R Espinoza-Gutarra et al.
Acute Myeloid Leukemia (AML) is a common hematologic neoplasm in adults and usually carries a grim prognosis. Therapy has traditionally consisted of intensive chemotherapy; however, recent advances have led to the development of Tyrosine Ki...
Association Between Petroleum Compounds Exposure and Risk of Childhood Leukemia: A Systematic Review [0.03%]
儿童白血病与石油化合物暴露关系的系统评价
Hossam Mohamed Hassan Soliman,Wesal Youssef Hassan,Marwa Mostafa et al.
Hossam Mohamed Hassan Soliman et al.
Childhood leukemia remains a critical public health concern, necessitating comprehensive evaluations of environmental risk factors. This systematic review aims to evaluate the epidemiological evidence regarding the relationship between comb...
Global Patterns, Temporal Trends, and Potential Non-Infectious Risk Factors for Burkitt Lymphoma from 1990 to 2021 [0.03%]
1990至2021年Burkitt淋巴瘤的全球模式、时间趋势及其潜在非传染性危险因素
Shi-Kai Jin,Jun-Ting Lyu,Zi-Yu Feng et al.
Shi-Kai Jin et al.
Background: The heterogeneity in the health burden and non-infectious risk factors of Burkitt lymphoma (BL) across sex, age, and geographic distribution remain inadequately understood. ...