Vitamin k antagonist warfarin for palliative treatment of metachromatic leukodystrophy, a compassionate study of four subjects [0.03%]
四种病患的代谢白质脑病的临终关怀治疗——华法林钾盐的作用力研究
Mitra Assadi,Dah-Jyuu Wang,Kelly Anderson et al.
Mitra Assadi et al.
MLD is characterized by accumulation of sulfatides in the brain. Vitamin K regulates two enzymes in sphingolipid biosynthesis and warfarin is known to lower brain sulfatides in rats and mice. We hypothesized that warfarin may mitigate the M...
Sentra PM (a Medical Food) and Trazodone in the Management of Sleep Disorders [0.03%]
Sentra PM（一种医疗食品）和曲唑酮在睡眠障碍管理中的应用
William E Shell,Lawrence A May,Debora H Bullias et al.
William E Shell et al.
Sleep disorders are a common and poorly treated disease state. This double blind, four arm placebo-controlled, randomized trial compared (1) low dose trazodone, (2) Sentra PM, a neurotransmitter based medical food, (3) the joint administrat...
The safety and tolerability of newer antiepileptic drugs in children and adolescents [0.03%]
新抗癫痫药在儿童及青少年中的安全性及其耐受性
Saima Kayani,Deepa Sirsi
Saima Kayani
Childhood epilepsy continues to be intractable in more than 25% of patients diagnosed with epilepsy. The introduction of new anti-epileptic drugs (AEDs) provides more options for treatment of children with epilepsy. We review the safety and...
R Shahien,K Beiruti
R Shahien
Migraine is among the 10 most disabling disorders worldwide. It is characterized by episodes of moderate or severe headaches with various degree of disability, resulting in a considerable health burden upon the sufferers and their family. T...
Hideo Matsuzaki,Keiko Iwata,Takayuki Manabe et al.
Hideo Matsuzaki et al.
This report reviews the research on the factors that cause autism. In several studies, these factors have been verified by reproducing them in autistic animal models. Clinical research has demonstrated that genetic and environmental factors...
M A Quera Salva,S Hartley
M A Quera Salva
Recent advances in the understanding of circadian rhythms have led to an interest in the treatment of major depressive disorder with chronobiotic agents. Many tissues have autonomous circadian rhythms, which are orchestrated by the master c...
Current and emerging therapies for the treatment of multiple sclerosis: focus on cladribine [0.03%]
多发性硬化症的当前和新兴疗法：聚焦克拉屈滨治疗
Teri L Schreiner,Augusto Miravalle
Teri L Schreiner
Multiple Sclerosis (MS) is a chronic inflammatory, immune-mediated, demyelinating disorder of the central nervous system with a heterogeneous clinical presentation and pathology in which activated lymphocytes play an important role in media...
Patient and Health Care Provider Perspectives on Long Acting Injectable Antipsychotics in Schizophrenia and the Introduction of Olanzapine Long-Acting Injection [0.03%]
患者和医护提供者对长效注射用抗精神病药物治疗精神分裂症的见解以及奥氮平长效注射制剂的引入
Heidi J Wehring,Sheryl Thedford,Maju Koola et al.
Heidi J Wehring et al.
Olanzapine long acting injection has joined risperidone and paliperidone as the second generation long acting antipsychotic injection options for treatment of patients with schizophrenia. Long acting injections are important alternatives to...