Heterogeneity of Microglia in Ischemic Stroke from the Perspective of Single-Cell RNA Sequencing: Subset Characteristics, Mechanisms and Therapeutic Potential [0.03%]
单细胞RNA测序视角下的缺血性卒中微环境中的小胶质细胞异质性：亚群特征、机制及治疗潜力
Daman Tian,Jiao Yang,Zhifeng Wang et al.
Daman Tian et al.
Ischemic stroke (IS), a predominant cerebrovascular disorder contributing to global disability and mortality, characterizes by a complex, multi-tiered cascade of pathological processes. As the primary innate immune cells within the central ...
Machine Learning-Based Detection of Parkinson's Disease From Arabic Speech: A Cross-Linguistic Validation Study [0.03%]
基于机器学习的帕金森病阿拉伯语语音检测：跨语言验证研究
Ahmad B Hassanat,Ahmad S Tarawneh,Enas Al-Khlifeh et al.
Ahmad B Hassanat et al.
Early detection of Parkinson's disease (PD) through speech analysis offers significant clinical advantages, yet no validated tools exist for Arabic-speaking populations, representing a critical gap in global healthcare. Previous studies hav...
Depression, Anxiety, and Stress After Acquired Brain Injury: The Role of Cognitive Reserve in Patients and Caregivers 'Symptoms [0.03%]
脑损伤后抑郁、焦虑和压力：认知储备在患者及照护者症状中的作用
Debora Bertoni,Benedetta Basagni,Sara Mondini et al.
Debora Bertoni et al.
Objectives: Severe acquired brain injury (sABI) can impact the psychological health not only in patients, but also in their caregivers. The present study was aimed at examining depression, anxiety and stress symptoms in p...
GLP-1 Receptor Agonists in Acute Ischemic Stroke and Secondary Stroke Prevention: A Narrative Review of Preclinical and Clinical Evidence [0.03%]
急性缺血性卒中和二级卒中预防中的胰高血糖素样肽-1受体激动剂：对临床前及临床证据的文献综述
Valentini Samanidou,Konstantinos Tsamis,Alexandr Ceasovschih et al.
Valentini Samanidou et al.
Background: Acute ischemic stroke (AIS) is a leading cause of death and disability. Glucagon-like peptide-1 receptor agonists (GLP-1RA) reduce atherosclerotic events in type 2 diabetes and obesity, and meta-analyses of ca...
Ofatumumab Treatment Used in Pediatric MOGAD: A Retrospective Case Series [0.03%]
儿科MOGAD患者使用奥法木单抗治疗的病例系列研究回顾
Wenlin Wu,Haixia Zhu,Chi Hou et al.
Wenlin Wu et al.
Background: Myelin oligodendrocyte glycoprotein antibody-associated disorder (MOGAD) is a rare central nervous system demyelinating disease with a variable course, including both monophasic and relapsing phenotypes. Effec...
Multiple Sclerosis in Charcot-Marie-Tooth Disease Type 1A - A Case Report and Literature Review [0.03%]
关于CMT1A并多发性硬化的病例报道及文献复习
Wen Yang,Lei Zhou,Gavin P Reynolds et al.
Wen Yang et al.
Central nervous system (CNS) demyelination is an uncommon observation in patients with Charcot-Marie-Tooth disease (CMT). Where it does occur, it is usually associated with X-linked CMT. We present a case of CMT type 1A with a likely de nov...
Modulation of EEG Background Rhythms in Sturge-Weber Syndrome: Impact of Surgical Timing on the Unaffected Hemisphere [0.03%]
Sturge-Weber综合征的脑电背景节律调控：手术时机对健康半球影响的不同效应
Jing Wang,Kun Lv,Zeming Wang et al.
Jing Wang et al.
Background: Epilepsy surgery improves seizure outcomes in Sturge-Weber syndrome (SWS), yet the electrophysiological patterns of postoperative recovery remain poorly characterized. Previous studies suggest that early inter...
Co-Existing Charcot-Marie-Tooth Disease Type II and Parkinson's Disease Linked to a Novel DNAjB2 Pathogenic Variant [0.03%]
新的DNAjB2致病突变联合导致夏科马里 tooth二型周围神经病和帕金森病病例报告
Alexandru N Lerint,Johanna S Canenguez Benitez,Vijaya Lakshmi Valaparla et al.
Alexandru N Lerint et al.
Background: The DNAjB2 gene encodes a co-chaperone protein that interacts with the heat shock protein (HSP) family to maintain protein quality control and preserve neuronal integrity. Variants in this gene have been assoc...
Assessing the Association of the Dietary Inflammatory Index With Stroke Risk and All-Cause Mortality Among Hypertension Patients: A NHANES Cross-Sectional Study (2005-2018) [0.03%]
基于NHANES横断面研究的高血压患者膳食炎症指数与脑卒中风险和全因死亡率关联分析（2005-2018）
Amu Jike,Shuming Wang,Erha Munai et al.
Amu Jike et al.
Objective: To investigate the association between the Dietary Inflammatory Index (DII) and stroke risk among hypertensive adults, as well as all-cause mortality post-stroke, utilizing data from the National Health and Nut...
Comparing the Efficacy and Safety of Endovascular Therapy Versus Best Medical Treatment in Acute Ischemic Stroke Patients With Distal Medium Vessel Occlusion: A Systematic Review and Meta-Analysis [0.03%]
急性缺血性卒中伴远端中动脉闭塞患者血管内治疗与最佳药物治疗有效性和安全性的系统评价和 meta 分析
Muhammad Hassan Waseem,Zain Ul Abideen,Eeshal Zulfiqar et al.
Muhammad Hassan Waseem et al.
Introduction: Distal Medium Vessel Occlusions (DMVOs) represent a significant subset of Acute Ischemic Stroke (AIS), with unique treatment challenges due to vessel size and location. While Endovascular Therapy (EVT) shows...