Pediatric Stroke in Asia and Africa: Epidemiology, Etiology, and Resource-Stratified Care Across Geographic and System-Level Disparities [0.03%]
亚洲和非洲的儿童卒中：地理和系统差异下的流行病学、病因及分层资源治疗
Anne Francine Pino,Afton Widdershins,Gayatra Mainali
Anne Francine Pino
Pediatric stroke is a rare but serious cause of morbidity and mortality, with disproportionately high burden in low- and middle-income countries (LMICs). Asia and Africa report the highest global incidence and prevalence, driven by region-s...
Pediatric Stroke in Asia and Africa: Epidemiology, Etiology, and Resource-Stratified Care Across Geographic and System-Level Disparities [0.03%]
亚洲和非洲的儿童卒中：地理及系统差异背景下的流行病学、病因及分层资源治疗方案
Anne Francine Pino,Afton Widdershins,Gayatra Mainali
Anne Francine Pino
Pediatric stroke is a rare but serious cause of morbidity and mortality, with disproportionately high burden in low- and middle-income countries (LMICs). Asia and Africa report the highest global incidence and prevalence, driven by region-s...
Factors Associated With Improved Physical Performance in Individuals With Parkinson's Disease Using the Fisior® Sequential Square Mat Walking Training Program: A Secondary Gender-Stratified Analysis of a Randomized Controlled Trial [0.03%]
基于性别分层分析的随机对照试验中使用Fisió®步态方格垫训练方案改善帕金森病患者运动表现的影响因素：次级结果分析
José Alegre-Tamariz,Carlos Ramírez-Moreno,Fernando M Runzer-Colmenares et al.
José Alegre-Tamariz et al.
Background: Variability in functional response to exercise interventions in Parkinson's disease (PD) remains poorly understood. Sex-related differences in motor performance and rehabilitation outcomes have been described ...
Neurodegeneration in Parkinson's Disease: The Role of Environmental Toxins [0.03%]
帕金森病中的神经退行性变：环境毒素的作用
Jamir Pitton Rissardo,Megan Katz,Vishnu Vardhan Byroju et al.
Jamir Pitton Rissardo et al.
Parkinson's disease (PD) is a rapidly growing global health challenge, with prevalence projected to reach 13-14 million cases by 2040. While aging and improved diagnostic awareness partly explain this trend, mounting evidence implicates env...
A Translational Readiness Checklist for Stem-Cell-Based Trials in Movement Disorders: A Practical Roadmap [0.03%]
干细胞治疗运动障碍的临床转化清单：实用路线图
Sahar Hemeda,József Janszky,Dávid Pintér et al.
Sahar Hemeda et al.
Stem cell-based therapies for movement disorders show inconsistent translation due to variations in product characterisation, delivery, endpoints, safety, and follow-up. Regulatory guidance provides principles but lacks a unified trial fram...
Construction and Validation of a Risk Prediction Model Incorporating Temporal Muscle Thickness for Adverse Outcome in Acute Ischemic Stroke Patients [0.03%]
结合时间肌厚度构建和验证急性缺血性卒中患者不良结局的风险预测模型
Huanpeng Wang,Yanchun Wu,Xiaojia Wu et al.
Huanpeng Wang et al.
Background: Sarcopenia significantly impacts stroke prognosis. Temporal muscle thickness (TMT) is an emerging metric for sarcopenia. Objectives: ...
Following Severe Pediatric Malaria, Epilepsy Screening Is Needed Even Among Children Without Coma: Findings From a Prospective Cohort Study [0.03%]
重度儿童疟疾后需要进行癫痫筛查：一项前瞻性队列研究的发现
Archana A Patel,Shaida Nishat,Rasesh B Joshi et al.
Archana A Patel et al.
Background: Severe pediatric malaria with neurological presentation has a spectrum of severity, from frank coma (Cerebral Malaria (CM)) to impaired consciousness and/or complex seizures without coma (malaria with central ...
The Impact of COVID-19 Infection and Vaccination on Neuromyelitis Optica Spectrum Disorder and Myelin Oligodendrocyte Glycoprotein Antibody Disease: A Narrative Review [0.03%]
COVID-19感染和疫苗接种对视神经脊髓炎谱系障碍及少突胶质细胞甘露糖蛋白抗体疾病的影响：综述文章
Jeffrey Hernandez,Silvia Delgado,Micheline McCarthy et al.
Jeffrey Hernandez et al.
Despite the estimated 776 million coronavirus disease 2019 (COVID-19) cases globally, little is known about its impact on immune-mediated neurological disorders such as neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocy...
Correlation Is Not Prediction: Reassessing Predictive MRI Evidence in Guidelines for Persons With Relapsing-Remitting Multiple Sclerosis [0.03%]
相关性并非预测性：重新评估在复发缓解型多发性硬化症患者指南中的预测性MRI证据
Dulat Minas,Stefan Buchka,Joachim Havla et al.
Dulat Minas et al.
Background: Effective treatment monitoring and treatment decisions in relapsing-remitting multiple sclerosis (RRMS) require accurate and individualized prediction of future disease courses. Guidelines from the Magnetic Re...
Beyond Time Is Brain: The Time, Tissue, and Systems Framework for Acute Stroke [0.03%]
时间已超出脑卒中的黄金治疗期：急性卒中治疗的时间、组织和系统框架
Sonu Bhaskar
Sonu Bhaskar
Acute ischaemic stroke care has long been guided by the maxim "time is brain," yet outcome variability suggests that clock time alone is insufficient. We propose the Time, Tissue, and Systems (TTS) framework, a quantitative model integratin...