The Impact of Baseline Vitamin D Level in Patients Receiving Gefitinib-Directed Therapy for EGFR-Mutant Non-Small-Cell Lung Cancer [0.03%]
基线维生素D水平对吉非替尼治疗EGFR突变型非小细胞肺癌的影响
Vanita Noronha,Manali Kolkur,R ArunKumar et al.
Vanita Noronha et al.
Background: There is contradicting evidence on vitamin D levels and cancer mortality rates. In this study, we aimed to evaluate the impact of baseline vitamin D level on the outcome in patients with estimated glomerular f...
Cost-Effectiveness Analysis of 6 Tyrosine Kinase Inhibitors as First-Line Treatment for ALK-Positive NSCLC in China [0.03%]
中国用于ALK阳性非小细胞肺癌一线治疗的六种酪氨酸激酶抑制剂的成本效益分析
Meiling Zhang,Bei Zheng,Wenjuan Yang et al.
Meiling Zhang et al.
Background: Lung cancer ranks first in both cancer incidence and mortality in China. The emergence of novel treatments for ALK-positive NSCLC led to an improvement in survival and quality of life for patients with advance...
RAS/RAF/MAPK Pathway Mutations as Predictive Biomarkers in Middle Eastern Colorectal Cancer: A Systematic Review [0.03%]
中东结直肠癌中RAS/RAF/MAPK通路突变作为预测性生物标志物的系统评价
Soukaina Benmokhtar,Abdelilah Laraqui,Farida Hilali et al.
Soukaina Benmokhtar et al.
Background: This review article aims to investigate the prevalence and spectrum of rat sarcoma (RAS) and V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) mutations, and their connection with geographical location, cli...
Utility of 18F-FDG PET/CT in Treatment Strategies for Patients With Cancer of Unknown Primary: A Single-Center, Retrospective Change-in-Management Study [0.03%]
18F-FDG PET/CT在原发不明癌症治疗策略中的应用价值：一项单中心回顾性改变管理研究
Rong Huang,Yuxiao Hu,Yun Zhang
Rong Huang
Background: Cancer of unknown primary (CUP) is difficult to diagnose and classify clinically, and the disease develops rapidly. Therefore, the primary tumor detected in patients with CUP plays a profound role in the diagn...
Min Zhang,Yuanhang Wang,Zhiyuan Song et al.
Min Zhang et al.
By modifying immune cells, immunotherapy can activate immune response to establish long-term immune memory and prevent tumor recurrence. However, their effectiveness is largely constricted by the poor immunogenicity, immune escape, and immu...
MiR-339-5p Inhibits Ferroptosis by Promoting Autophagic Degradation of FTH1 Through Targeting ATG7 in Liver Cancer Cells [0.03%]
MiR-339-5p通过靶向ATG7促进FTH1自噬降解从而抑制肝癌细胞铁死亡
Fei Cao,Weiyuan Hao,Weiren Liang et al.
Fei Cao et al.
Background: Liver cancer has a high incidence and mortality rate worldwide, and there is an urgent need to identify new therapeutic strategies and predictive targets to improve the clinical outcomes of advanced liver canc...
Prediction of High-Risk Gastrointestinal Stromal Tumor Recurrence Based on Delta-CT Radiomics Modeling: A 3-Year Follow-up Study After Surgery [0.03%]
基于Delta-CT影像组学模型预测胃肠道间质瘤术后高危复发：为期三年的随访研究
Xianqun Ji,Yu Shang,Lin Tan et al.
Xianqun Ji et al.
Background: Medium- to high-risk classification-gastrointestinal stromal tumors (MH-GIST) have a high recurrence rate and are difficult to treat. This study aims to predict the recurrence of MH-GIST within 3 years after s...
Diagnostic Performance of Node Reporting and Data System Magnetic Resonance Imaging Score in Detecting Metastatic Cervical Lymph Nodes of Nasopharyngeal Carcinoma [0.03%]
鼻咽癌颈淋巴结转移的磁共振影像评分诊断价值分析
Xinggang Yang,Jiaqing Yang,Jia Li et al.
Xinggang Yang et al.
Background: The Node Reporting and Data System (Node-RADS) is a recently proposed classification system for the categorization of lymph nodes in radiological images. This study was conducted to retrospectively evaluate th...
Helicobacter pylori and Gastrointestinal Cancers: Recent Advances and Controversies [0.03%]
幽门螺旋杆菌与胃肠道癌症：近期进展和争议点
Chuandong Zhang,Yuqi Chen,Yan Long et al.
Chuandong Zhang et al.
Helicobacter pylori (H pylori), a gastric bacterium, has been extensively studied for its association with gastritis, peptic ulcers, and gastric cancer. However, recent evidence suggests its potential implications beyond the stomach, linkin...
Cardiac Morbidity and Mortality in Patients with Sarcoma: A Population-Based Study [0.03%]
基于人群的肉瘤患者心脏发病率和死亡率研究
Rakan Alanazi,Ahmed Aljizeeri,Ahmed Alsaileek et al.
Rakan Alanazi et al.
Background: Soft tissue sarcoma (STS) is a rare malignancy that affects soft tissues. It encompasses various subtypes and requires different treatment strategies. Doxorubicin is a commonly used anthracycline in the manage...