Bevacizumab Plus EGFR-TKIs vs EGFR-TKIs Alone for Advanced EGFR-Mutant NSCLC: A Meta-Analysis [0.03%]
贝伐单抗联合表皮生长因子受体酪氨酸激酶抑制剂对比单纯表皮生长因子受体酪氨酸激酶抑制剂治疗晚期表皮生长因子受体突变型非小细胞肺癌： meta分析
Zexian Wang,Yaru Guo,Xiaohan Qin et al.
Zexian Wang et al.
Background: The goal of this comprehensive meta-analysis was to evaluate the efficacy and safety of combining Epidermal Growth Factor Receptor (EGFR)-tyrosine kinase inhibitors (TKIs) with bevacizumab vs EGFR-TKI monother...
Clinical Analysis of Peripheral Blood Indicators for Immune-Related Adverse Events (irAEs) in Patients With Advanced Lung Cancer [0.03%]
晚期肺癌患者免疫相关不良事件(irAEs)外周血指标的临床分析
Yin-Min Ji,Yu-Hui Qin,Ya-Hui Lv et al.
Yin-Min Ji et al.
Background: Immune checkpoint inhibitors (ICIs) have revolutionized advanced lung cancer treatment, but immune-related adverse events (irAEs) remain a significant challenge. This study aimed to identify peripheral blood i...
Effectiveness and Safety of Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma: A Multicenter, Retrospective Real-World Study in China [0.03%]
阿特朱单抗联合贝伐珠单抗治疗不可切除的肝细胞癌的有效性和安全性：中国多中心真实世界回顾性研究
Minghua Shao,Binbin Tan,Chao Fan et al.
Minghua Shao et al.
Background: Atezolizumab combined with bevacizumab (Atezo + Bev) has received regulatory approval as a first-line systemic therapy for unresectable hepatocellular carcinoma. This study aimed to evaluate the effectiveness ...
Development of Nomogram for Predicting Postoperative Progression Risk in High-Risk Thymoma and Thymic Carcinoma Utilizing Clinical and Preoperative CT Features [0.03%]
基于临床和术前CT特征的高危胸腺瘤及胸腺癌术后复发风险预测列线图的建立
Qian Meng,Nan Jiang,Jun Chen et al.
Qian Meng et al.
Background: Computed tomography (CT) features and clinical characteristics have been shown in recent studies to be effective predictive indicators for risk stratification of thymic epithelial tumors. High-risk thymoma and...
Prediction Model for Low Bone Mineral Density in Cancer Survivors and Age-Matched Controls Using a Causal Bayesian Network: A Nationwide Population-Based Study in Korea [0.03%]
基于因果贝叶斯网络的癌症幸存者和同龄对照组低骨矿质密度预测模型的全国人口为基础的研究
Sujeong Han,Sung-Bae Park,Sohee Oh et al.
Sujeong Han et al.
Background: With advances in cancer treatment, the number of cancer survivors has increased, bringing attention to long-term complications such as alterations in bone mineral density (BMD). Although survivors are at eleva...
Beta-Blocker Use and Survival Outcomes in Pancreatic Cancer Patients: A Systematic Review and Meta-Analysis [0.03%]
β受体阻滞剂的使用与胰腺癌患者预后之间的关系：系统评价和 meta 分析
Rui Li,Jie Chen,Yingkai Chen et al.
Rui Li et al.
Background: Pancreatic cancers (PCs)-especially pancreatic ductal adenocarcinoma (PDAC)-are among the deadliest digestive system cancers, with a 5 year survival of approximately 13%. Beta blockers (BBs), which inhibit bet...
Efficacy and Safety of Ribociclib Plus Endocrine Therapy Versus Endocrine Therapy Alone in HR-Positive/HER2-Negative Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [0.03%]
ribociclib联合内分泌治疗与单纯内分泌治疗在HR阳性/HER2阴性乳腺癌中疗效和安全性的系统评价和meta分析
Reechashree Dhungana,Parikshit Prasai,Bishal Paudel et al.
Reechashree Dhungana et al.
Background: Recent trials of ribociclib, a cyclin-dependent kinase inhibitor, have shown promising results in patients with hormone receptor-positive (HR+)/HER2-negative (HER2-) breast cancer. This meta-analysis evaluates...
Colonic Gastrointestinal Stromal Tumors Demonstrate Unique Biological Characteristics: A Retrospective, Propensity Score-Matched Cohort Study Pooling Multicenter and Literature-Derived Individual Patient Data [0.03%]
结肠胃肠间质瘤具有独特的生物学特征：一项基于多中心及文献个体患者数据汇总的回顾性倾向性匹配队列研究
Zhuo-Fei Li,Guo-Shuai Chen,Han Li et al.
Zhuo-Fei Li et al.
Background: Colonic gastrointestinal stromal tumors (cGISTs) represent an exceptionally rare subtype of gastrointestinal stromal tumors (GISTs) and exhibit distinct clinicopathological features. Nonetheless, limited resea...
Predictive Value of Patient-Derived Tumor Cell Cluster-Based Drug Sensitivity Assay in Advanced NSCLC [0.03%]
基于患者来源肿瘤细胞团的药物敏感性检测在晚期非小细胞肺癌中的预测价值
Yangchun Gu,Leilei Yang,Hua Zhang et al.
Yangchun Gu et al.
Background: Patient-derived tumor cell cluster (PTC)-based drug sensitivity assays show promise for enabling precision drug selection; however, their predictive value in advanced non-small cell lung cancer (NSCLC) require...
Machine Learning-Based Enhanced MRI Radiomics for PDCD1 Prognostication and Expression Prediction in Breast Cancer [0.03%]
基于机器学习的增强型MRI影像组学在乳腺癌PDCD1预后和表达预测中的应用
Yingying Gao,Zihan Li,Ziyun Li et al.
Yingying Gao et al.
Background: Programmed cell death 1 (PDCD1) is an immune checkpoint inhibitor that plays an important role in immune evasion in breast cancer (BC). In this study, we aimed to evaluate the correlation between PDCD1 express...