Cisplatin and Alternating Temozolomide in Recurrent High-Grade Gliomas: Efficacy and the Role of Tumor-Infiltrating Lymphocytes in a Phase II Clinical Trial [0.03%]
复发性高级别脑胶质瘤的顺铂和替莫唑胺交替治疗：II期临床试验的有效性和肿瘤浸润淋巴细胞的作用
Xiaojie Ding,Di Chen,Zhenyu Zhang et al.
Xiaojie Ding et al.
Background: To evaluate the efficacy and safety of cisplatin combined with alternating temozolomide (TMZ) for recurrent high-grade glioma, as current treatments lack standardized protocols and predictive markers. ...
Response to Comment on "Artificial Intelligence Can Facilitate Application of Risk Stratification Algorithms to Bladder Cancer Patient Case Scenarios" [0.03%]
关于“人工智能可以促进风险分层算法在膀胱癌病例场景中应用”的评论答复
Max S Yudovich,Ahmad N Alzubaidi,Jay D Raman
Max S Yudovich
Comment on: "Artificial Intelligence Can Facilitate Application of Risk Stratification Algorithms to Bladder Cancer Patient Case Scenarios" [0.03%]
对“人工智能可以促进风险分层算法在膀胱癌病例场景中的应用”的评论
Hinpetch Daungsupawong,Viroj Wiwanitkit
Hinpetch Daungsupawong
Real-World Efficacy and Safety of S-1 Monotherapy in Non-Small Cell Lung Cancer Management: Insights From a Multicenter Retrospective Cohort Study [0.03%]
一项多中心回顾性队列研究：S-1单药治疗非小细胞肺癌的疗效和安全性分析
I-Lin Tsai,Chien-Yu Lin,Po-Lan Su et al.
I-Lin Tsai et al.
Background: S-1, an oral chemotherapy combining tegafur, gimeracil, and oteracil, has shown efficacy comparable with docetaxel for advanced non-small cell lung cancer (NSCLC) in clinical trials. However, its real-world ef...
WD40 Protein NLE1 as a Novel Diagnostic Biomarker Promoting Hepatocellular Carcinoma Proliferation [0.03%]
WD40蛋白NLE1作为促进肝细胞癌增殖的新诊断生物标志物
Rutong Zhang,Dehua Liu,Xiaoxi Feng et al.
Rutong Zhang et al.
Background: Hepatocellular carcinoma (HCC) is associated with poor prognosis and high mortality. Notchless homolog 1 (NLE1) is an important WD40 protein. Although several studies have shown that NLE1 is dysregulated in ca...
Contribution of TP53 and MDM4 Genetic Polymorphisms as a Risk Factor in Non-Hodgkin Lymphoma in Adult Egyptian Patients [0.03%]
TP53和MDM4基因多态性在成年埃及非霍奇金淋巴瘤患者中的致病风险研究
Eman A Helal,Naglaa M Hassan,Mahmoud M Kamel et al.
Eman A Helal et al.
Background: Non-Hodgkin Lymphoma (NHL) is an increasingly prevalent hematological malignancy in Egypt, highlighting the need for a better understanding of its genetic risk factors. The TP53 and MDM4 genes play critical ro...
Role of Oral and Esophageal Microbiota in Esophageal Squamous Cell Carcinoma [0.03%]
口腔及食道菌群在食管鳞癌发生中的作用研究进展
Kong Jinyu,Wang Jian,Liu Yiwen et al.
Kong Jinyu et al.
In China, esophageal cancer (EC) is one of the most prevalent malignant tumors of the digestive system. EC has a high incidence and mortality rate, of which esophageal squamous cell carcinoma (ESCC) accounts for more than 90%. Due to a lack...
Jakub Karwacki,Justyna Kiełbasa,Zuzanna Szczepaniak et al.
Jakub Karwacki et al.
Cryoablation is gaining attention as a minimally invasive treatment option for prostate cancer (PCa), offering a balance between effective oncological control and preserving genitourinary functions and quality of life. Focal cryoablation is...
The Role of Allogeneic Stem Cell Transplantation in Adult Patients With Peripheral T-Cell Lymphoma: A Systematic Review and Meta-Analysis [0.03%]
异基因干细胞移植治疗成人外周T细胞淋巴瘤患者的疗效分析：系统评价和Meta分析
Ahmad Alazzam,Mosab Said,Mohammad AlElaimat et al.
Ahmad Alazzam et al.
Objectives: Peripheral T-cell lymphomas (PTCLs) are rare, aggressive non-Hodgkin lymphomas with limited treatment options and poor prognosis, especially upon relapse. Both autologous and allogeneic stem cell transplants h...
Primary Management of Localized Gastrointestinal Stromal Tumors With Imatinib Monotherapy: An Alternative to Resection of Patients Precluded From Surgery [0.03%]
伊马替尼单药作为手术禁忌的局部胃肠道间质瘤患者的主要治疗手段
John S Wang,Brandon L Ellsworth,Rusul Al-Marayaty et al.
John S Wang et al.
Background: In this study, our goal was to elucidate the role for imatinib monotherapy for treatment of patients with localized gastrointestinal stromal tumors (GISTs) who are precluded from standard-of-care surgical rese...