Joseph F Murphy
Joseph F Murphy
Modulation of the immune system for therapeutic ends has a long history, stretching back to Edward Jenner's use of cowpox to induce immunity to smallpox in 1796. Since then, immunotherapy, in the form of prophylactic and therapeutic vaccine...
CD4 Count and Anti Retroviral Therapy for HIV Positive Patients With Cancer in Nigeria -A Pilot Study [0.03%]
尼日利亚HIV阳性肿瘤患者的CD4计数和抗逆转录病毒治疗-一项初步研究
Atara I Ntekim,Ayo M Folasire
Atara I Ntekim
Background: Highly Active Anti Retroviral Treatment (HAART) improves the outcome of HIV positive patients treated for cancer. In our center HAART is only commenced in HIV positive patients with malignancy if the CD4 T lym...
Early Diagnosis of Invasive Aspergillosis in Neutropenic Patients. Comparison between Serum Galactomannan and Polymerase Chain Reaction [0.03%]
中性粒细胞减少患者侵袭性曲霉病的早期诊断：血清半乳糖甘露聚糖检测与聚合酶链反应比较
Rodrigo Lopes da Silva,Patrícia Ribeiro,Natacha Abreu et al.
Rodrigo Lopes da Silva et al.
Background: Invasive aspergillosis (IA) is a major cause of morbidity and mortality in profoundly neutropenic patients, so early diagnosis is mandatory. A...
Z Nahleh,J Pruemer,J Lafollette et al.
Z Nahleh et al.
Purpose: Melatonin has neuroprotective effects in animal studies and has been suggested to decrease adverse reactions of chemotherapy including neuropathy. This pilot trial aimed at assessing whether melatonin, given duri...
Classical and Novel Prognostic Markers for Breast Cancer and their Clinical Significance [0.03%]
经典和新颖的乳腺癌预后标志物及其临床意义
Pankaj Taneja,Dejan Maglic,Fumitake Kai et al.
Pankaj Taneja et al.
The use of biomarkers ensures breast cancer patients receive optimal treatment. Established biomarkers such as estrogen receptor (ER) and progesterone receptor (PR) have been playing significant roles in the selection and management of pati...
Hemorrhagic cystitis in a patient receiving docetaxel for prostate cancer [0.03%]
多西他赛治疗前列腺癌引起的出血性膀胱炎
A I Ntekim,A Ajekigbe
A I Ntekim
A case is reported in which docetaxel was used to treat a patient with hormone refractory metastatic prostate cancer. The treatment was terminated at the third course of docetaxel following the development of hemorrhagic cystitis. This reac...
A Phase II Study of S-1 Monotherapy as a First-line Combination Therapy of S-1 Plus Cisplatin as a Second-line Therapy, and Weekly Paclitaxel Monotherapy as a Third-line Therapy in Patients with Advanced Gastric Carcinoma: A Second Report [0.03%]
S-1单药作为一线治疗、S-1联合顺铂作为二线治疗以及三线每周紫杉醇单药治疗晚期胃癌患者的II期临床研究第二篇报告
Yasushi Rino,Norio Yukawa,Hitoshi Murakami et al.
Yasushi Rino et al.
Background: We have previousy reported on a Phase II study of S-1 monotherapy as a first line, combination therapy of S-1 plus cisplatin as a second line, and weekly paclitaxel monotherapy as a third line therapy in patie...
Significance of GSTM1 and GSTT1 Gene Deletions in Glioma Patients in Polish Population: Pilot Study [0.03%]
波兰人群胶质瘤患者中GSTM1和GSTT1基因缺失的意義：初步研究
Background: Detoxification enzymes of the glutathione S-transferase (GST) family are cytosolic phase II detoxification enzymes and play an important role in the normal functioning of the human antioxidant system. When the...
The Clinical Impact of Heart Failure on the Postoperative Outcomes for Lung Cancer Patients Undergoing Lobectomy and Sublobar Resection by Video-Assisted Thoracic Surgery: A Propensity Score-Matched Analysis of 2016-2020 HCUP-NIS Data [0.03%]
基于2016-2020年HCUP-NIS数据的倾向性匹配分析：心脏衰竭对胸腔镜解剖性肺叶切除和亚肺叶切除术后肺癌患者预后的影响临床研究
Background: The clinical impact of heart failure (HF) on postoperative outcomes following video-assisted thoracic surgery (VATS) for lung cancer resection remains controversial. This study aimed to assess patient and hosp...