Review of the management of relapsed small-cell lung cancer with amrubicin hydrochloride [0.03%]
氨柔比星治疗小细胞肺癌复发的文献回顾
Tatsuo Kimura,Shinzoh Kudoh,Kazuto Hirata
Tatsuo Kimura
Lung cancer is the leading cause of cancer death, and approximately 15% of all lung cancer patients have small-cell lung cancer (SCLC). Although second-line chemotherapy can produce tumor regression, the prognosis is poor. Amrubicin hydroch...
The emerging role of ofatumumab in the treatment of chronic lymphocytic leukemia [0.03%]
Ofatumumab在慢性淋巴细胞白血病治疗中的作用不容小觑
Chadi Nabhan,Neil E Kay
Chadi Nabhan
The treatment of chronic lymphocytic leukemia (CLL) has evolved over the past decade. Our better understanding of disease biology and risk stratification has allowed delivering more effective therapies. In fact, front-line chemoimmunotherap...
The combined influence of oral contraceptives and human papillomavirus virus on cutaneous squamous cell carcinoma [0.03%]
口服避孕药和人类乳头瘤病毒对皮肤鳞状细胞癌的联合影响
Jimmy T Efird,Amanda E Toland,C Suzanne Lea et al.
Jimmy T Efird et al.
The vast majority of cutaneous squamous cell carcinoma (CSCC) will occur in those with fair complexion, tendency to burn, and high ultraviolet radiation (UVR) exposure. Organ transplant recipients also are an important population at great r...
Esther Uña Cidón,Christian Perea,Francisco López-Lara
Esther Uña Cidón
Background: In recent years, breast cancer (BC) mortality rates have declined, reflecting advances in early detection. Prevention and management of treatment sequelae that could impair function or quality of life have inc...
The use of patient navigators to improve cancer care for Hispanic patients [0.03%]
使用患者引导员改善西班牙裔癌症患者护理的效果
Loreley Robie,Daniela Alexandru,Daniela A Bota
Loreley Robie
Background: Although the United States is one of the countries at the leading edge of medical breakthroughs and treatments, there are great disparities in the access to care among different socioeconomic strata. One of th...
Early Detection of t(8;21) Chromosomal Translocations During Treatment of PML-RARA Positive Acute Promyelocytic Leukemia: A Case Study [0.03%]
PML-RARA阳性急性早幼粒细胞白血病治疗期间早期检测t(8;21)染色体易位的病例报告
Walter Kleine Neto,Mariana Serpa,Sabri Saeed Sanabani et al.
Walter Kleine Neto et al.
Here we describe a female patient who developed acute promyelocytic leukemia (APL) characterized by t(l5;17) translocation at diagnosis. The patient began treatment with all-trans retinoic acid (ATRA) + chemotherapy. During follow up, the p...
Efficacy and tolerability after unusually low doses of dasatinib in chronic myeloid leukemia patients intolerant to standard-dose dasatinib therapy [0.03%]
对标准剂量达沙替尼治疗不耐受的慢性髓性白血病患者小剂量达沙替尼疗效及耐受性的研究
Mariana Serpa,Sabri S Sanabani,Israel Bendit et al.
Mariana Serpa et al.
We report our experience in 4 patients with chronic myeloid leukemia (CML) who had discontinued imatinib as a result of adverse events and had switched to dasatinib. The chronic phase (n 2) and accelerated phase (n 2) CML patients received ...
Julien Hadoux,Stephane Vignot,Thibault De La Motte Rouge
Julien Hadoux
Metastatic renal cell carcinoma has harboured a poor prognosis for decades with immunotherapy being the only available therapy with high toxicity and modest effect. Dependance of renal cell carcinoma oncogenesis on the mTOR pathway has led ...
Esther Uña,Francisco López-Lara
Esther Uña
Background: Rectal cancer is a highly prevalent disease which needs a multidisciplinary approach to be treated. The absence of specific protocols implies a significant and unjustifiable variability among the different pro...
Andrew M Roecker,Amy Stockert,David F Kisor
Andrew M Roecker
Nelarabine is a nucleoside analog indicated for the treatment of adult and pediatric patients with T-cell acute lymphoblastic leukemia (T-ALL) or T-cell lymphoblastic lymphoma (T-LBL) that is refractory or has relapsed after treatment with ...