Three Cases of Combined Therapy in Primary Breast Lymphoma (PBL) with Successful Outcomes [0.03%]
三例成功治疗原发性乳腺淋巴瘤(PBL)的综合疗法报告
Zorka Inic,Momcilo Inic,Milan Zegarac et al.
Zorka Inic et al.
Primary malignant lymphoma of the breast is a rare tumor, defined as a tumor localized in the breast with or without axillary lymph-node metastases. Such a tumor is mainly found in female patients and located more frequently in the right br...
A six-year study of the clinical presentation of cervical cancer and the management challenges encountered at a state teaching hospital in southeast Nigeria [0.03%]
尼日利亚东南部一所国家教学医院宫颈癌临床表现及治疗挑战六载研究
Justus N Eze,Esther N Emeka-Irem,Felix O Edegbe
Justus N Eze
Cervical cancer is still a major contributor to cancer-related mortality amongst women living in poor, rural communities of developing countries. The objective of this study is to establish the clinical presentation of cervical cancer and t...
April K S Salama
April K S Salama
Metastatic melanoma remains a difficult disease to treat, and long term survivors are rare. Over the past few years, however, breakthroughs in both immunotherapy as well as targeted agents have had a tremendous impact on patients diagnosed ...
Miguel J Gil-Gil,Carlos Mesia,Montserrat Rey et al.
Miguel J Gil-Gil et al.
Glioblastoma (GBM) or grade IV glioma is the most common primary brain tumor in adults. Standard treatment median overall survival (OS) is only 14-15 months and less than 10% of patients will survive 5 years after diagnosis. There is no sta...
Recent progress in mouse models for tumor suppressor genes and its implications in human cancer [0.03%]
肿瘤抑制基因的小鼠模型研究进展及其对人类癌症的意义
Kazushi Inoue,Elizabeth A Fry,Pankaj Taneja
Kazushi Inoue
Gain-of-function mutations in oncogenes and loss-of-function mutations in tumor suppressor genes (TSG) lead to cancer. In most human cancers, these mutations occur in somatic tissues. However, hereditary forms of cancer exist for which indi...
Zhengyu Wei,Cataldo Doria,Yuan Liu
Zhengyu Wei
Hepatocellular carcinoma (HCC) is the most common liver cancer and the third leading cause of cancer death. It has been a major worldwide health problem with more new cases being diagnosed each year. The current available therapies for pati...
Peripheral helper lymphocytes produce interleukin 12 in cancer patients [0.03%]
癌症患者的周边辅助淋巴细胞产生白细胞介素12
Márcia A Michelin,Douglas R Abdalla,André A R Aleixo et al.
Márcia A Michelin et al.
The aim of the study was to seek evidence for the production of IL-12 by CD4(+) T lymphocytes in in vitro and ex vivo trials. We performed in vitro trials with spleen cells from mice subjected to carcinogenesis, as well as ex vivo trials wi...
Efficacy of bortezomib as first-line treatment for patients with multiple myeloma [0.03%]
硼替佐米作为多发性骨髓瘤初治患者诱导治疗的疗效分析
Utkarsh Painuly,Shaji Kumar
Utkarsh Painuly
Recent years have seen a dramatic change in the approach towards diagnosing and treating Multiple Myeloma. Newer and more target specific approach to treatment has prolonged the survival for patients with multiple myeloma. The proteasome in...
Erik J Blok,Peter Jk Kuppen,Jeroen Em van Leeuwen et al.
Erik J Blok et al.
Trastuzumab, a humanized mouse monoclonal antibody directed against HER2 (Human Epidermal Growth Factor Receptor 2), is currently a keystone in the treatment of breast cancer. Meanwhile, trastuzumab has been validated for use in other types...