Targeting Bone Metastases in Metastatic Castration-Resistant Prostate Cancer [0.03%]
转移性去势抵抗性前列腺癌骨转移的治疗
Joelle El-Amm,Jeanny B Aragon-Ching
Joelle El-Amm
Skeletal involvement in metastatic castrate-resistant prostate cancer (mCRPC) is common and results in significant morbidity and mortality. The interaction of prostate cancer with the bone microenvironment contributes to progression of canc...
Resistance to Novel Antiandrogen Therapies in Metastatic Castration-Resistant Prostate Cancer [0.03%]
转移性去势抵抗性前列腺癌患者新型抗雄激素治疗的耐药性
Karim Boudadi,Emmanuel S Antonarakis
Karim Boudadi
Despite the introduction of novel therapies that maximally decrease androgen-receptor (AR) signaling activity, metastatic castration-resistant prostate cancer (mCRPC) remains a lethal disease. Even though abiraterone and enzalutamide repres...
Molecular Analysis of Central Nervous System Disease Spectrum in Childhood Acute Lymphoblastic Leukemia [0.03%]
儿童急性淋巴细胞白血病中枢神经系统疾病谱的分子分析
Chindo Hicks,Jitsuda Sitthi-Amorn,Jessica Douglas et al.
Chindo Hicks et al.
Treatment of the central nervous system (CNS) is an essential therapeutic component in childhood acute lymphoblastic leukemia (ALL). The goal of this study was to identify molecular signatures distinguishing patients with CNS disease from t...
A Rare Occurrence of Simultaneous Venous and Arterial Thromboembolic Events - Lower Limb Deep Venous Thrombosis and Pulmonary Thromboembolism as Initial Presentation in Acute Promyelocytic Leukemia [0.03%]
急性早幼粒细胞白血病并发下肢深静脉血栓形成和肺动脉栓塞作为起病初发症状的罕见病例报告
Aditya S Kutiyal,Pramila Dharmshaktu,Babita Kataria et al.
Aditya S Kutiyal et al.
The development of acute myeloid leukemia has been attributed to various factors, including hereditary, radiation, drugs, and certain occupational exposures. The association between malignancy and venous thromboembolism events is well estab...
Delaying Chemotherapy in the Treatment of Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer [0.03%]
治疗激素受体阳性、人表皮生长因子受体2阴性的晚期乳腺癌时推迟化疗的效果
Adam M Brufsky
Adam M Brufsky
Global guidelines for the management of locally advanced or metastatic hormone receptor-positive (HR-positive), human epidermal growth factor 2-negative (HER2-negative) breast cancer recommend endocrine therapy as first-line treatment for a...
William C Cho
William C Cho
An Unusual Case of Hepatosplenic αβ T-Cell Lymphoma Presenting with Coombs'-Negative Hemolytic Anemia [0.03%]
一名以Coombs'试验阴性溶血性贫血表现为肝脾T细胞淋巴瘤的罕见病例报告
Feryal A Ibrahim,Vignesh Shanmugam,Aliaa Amer et al.
Feryal A Ibrahim et al.
Hepatosplenic T-cell lymphoma (HSTCL) is a rare and aggressive extranodal T-cell lymphoma that comprises
Akira Tadokoro,Nobuhiro Kanaji,Tomoya Ishii et al.
Akira Tadokoro et al.
We report a case of squamous cell lung cancer with transbronchial dissemination in a 73-year-old man. Bronchoscopic examination revealed multiple bronchial mucosal nodules that existed independently of one another. We reviewed 16 previous c...
Hafiz Ahmed,Dina M M AlSadek
Hafiz Ahmed
Interactions between two cells or between cell and extracellular matrix mediated by protein-carbohydrate interactions play pivotal roles in modulating various biological processes such as growth regulation, immune function, cancer metastasi...
Obesity Correlation With Metastases Development and Response to First-Line Metastatic Chemotherapy in Breast Cancer [0.03%]
肥胖与乳腺癌转移发生及一线转移性化疗疗效的相关性研究
Mohammed A Osman,Bryan T Hennessy
Mohammed A Osman
Study objectives: To compare breast cancer metastases between obese and nonobese women and to evaluate the effect of first-line metastatic chemotherapy in each group. ...