A Diagnostic Nomogram of Pathologic Grade for Preoperative Risk Stratification in Upper Tract Urothelial Carcinoma [0.03%]
上尿路尿道上皮癌病理分级诊断nomogram对术前危险分层的应用研究
Runzhuo Ma,Haizhui Xia,Min Qiu et al.
Runzhuo Ma et al.
Background: To develop a novel nomogram to improve the preoperative diagnosis of pathological grade of upper tract urothelial carcinoma (UTUC). Methods: ...
Joanna S Lee,Osman Toktas,Atilla Soran
Joanna S Lee
It is estimated that approximately 154000 women in the United States have stage IV breast cancer (BC). A subset of this group has metastatic disease at presentation, known as de novo stage IV disease. De novo stage IV BC accounts for approx...
Otto C Burghuber,Klaus Kirchbacher,Andrea Mohn-Staudner et al.
Otto C Burghuber et al.
Objectives: The Austrian Lung Cancer Audit (ALCA) is a pilot study to evaluate clinical and organizational factors related to lung cancer care across Austria. ...
Central Venous Catheter Thrombosis in Cancer: A Multi-Centre Retrospective Study Investigating Risk Factors and Contemporary Trends in Management [0.03%]
癌症患者的中央静脉导管血栓形成:一项多中心回顾性研究探讨危险因素及目前的管理趋势
Lucy Haggstrom,Gurdeep Parmar,Daniel Brungs
Lucy Haggstrom
Objectives: Central venous access is needed to facilitate chemotherapy for many cancer patients. Central venous catheter-related thrombosis (CVCT) is a major complication that can cause significant morbidity and mortality...
Genetic Heterogeneity Between Paired Primary and Brain Metastases in Lung Adenocarcinoma [0.03%]
肺腺癌配对原发灶与脑转移灶之间的遗传异质性
Li Li,Zhulin Liu,Rui Han et al.
Li Li et al.
Purpose: About one-third of nonsmall cell lung cancer (NSCLC) patients develop brain metastases (BM). However, there is an unmet need for early diagnosis and treatment of BM. The precise mechanism for BM is still unknown....
Efficacy of Docetaxel Plus Ramucirumab as Palliative Third-Line Therapy Following Second-Line Immune-Checkpoint-Inhibitor Treatment in Patients With Non-Small-Cell Lung Cancer Stage IV [0.03%]
多西他赛联合雷莫芦单抗作为二线免疫检查点抑制治疗后晚期非小细胞肺癌三线姑息治疗的疗效研究
Wolfgang M Brueckl,Martin Reck,Achim Rittmeyer et al.
Wolfgang M Brueckl et al.
Background: Antiangiogenic agents have been shown to stimulate the immune system and cause synergistic effects with chemotherapy. Effects might be even stronger after immune-checkpoint-inhibitor (ICI) therapy. The purpose...
Anti-EGFR Therapy in Metastatic Small Bowel Adenocarcinoma: Myth or Reality? [0.03%]
抗EGFR治疗在转移性小肠腺癌中的应用:神话还是现实?
Emanuela DellAquila,Tea Zeppola,Marco Stellato et al.
Emanuela DellAquila et al.
Background: Due to the relative rarity of small bowel adenocarcinoma (SBA), prospective trials, helping to guide therapeutic decisions, are lacking and the optimal therapy for advanced SBA is unknown. The role of targeted...
Gut Microbiota and Response to Immunotherapeutic Drugs in Oncology: More Questions Than Answers [0.03%]
肿瘤免疫治疗药物与肠道微生物群:更多的问题还是答案?
Dhiraj Abhyankar,Kelly T McKee Jr,Pavle Vukojevic
Dhiraj Abhyankar
Immuno-oncology drugs (IODs) have revolutionized the treatment of some cancers. Although IODs are enabling some patients with cancer to become long-time survivors, only 30% to 40% respond to these drugs. There is experimental and clinical e...
The Impact of Prolonged Chemotherapy to Surgery Interval and Neoadjuvant Radiotherapy on Pathological Complete Response and Overall Survival in Pancreatic Cancer Patients [0.03%]
新辅助放疗及术前长期化疗对胰腺癌患者病理完全缓解和总生存的影响
Basem Azab,Francisco Igor Macedo,David Chang et al.
Basem Azab et al.
Background: We aimed to study the impact of neoadjuvant chemotherapy to surgery (NCT-S) interval and neoadjuvant radiotherapy (NRT) on pathological complete response (pCR) and overall survival (OS) in pancreatic cancer (p...
Current State of the Art in the Adjuvant Systemic Treatment of Premenopausal Patients With Early Breast Cancer [0.03%]
早发型乳腺癌患者术前辅助系统治疗的现状及进展
Francesca Parisi,Maria Grazia Razeti,Eva Blondeaux et al.
Francesca Parisi et al.
Breast cancer is the most frequent malignancy diagnosed in premenopausal women. In this age group, breast tumors tend to be diagnosed at more advanced stages and to harbor more aggressive biological features. In addition, specific age-relat...