Igniting Hope for Tumor Immunotherapy: Promoting the "Hot and Cold" Tumor Transition [0.03%]
点燃肿瘤免疫治疗希望促进“冷热”肿瘤转换
Chen Wei,Yichao Ma,Fei Wang et al.
Chen Wei et al.
The discovery of immune checkpoint inhibitors (ICIs) has ushered a new era for immunotherapy against malignant tumors through the killing effects of cytotoxic T lymphocytes in the tumor microenvironment (TME), resulting in long-lasting tumo...
Chemotherapy for Metastatic Gastric Cancer: Does Age Matter? A Single-Center, Retrospective, Real-World Study [0.03%]
转移性胃癌的化疗：年龄有关系吗？一项单中心回顾性真实世界研究
Po-Wei Liao,Shao-Bin Cheng,Cheng-Wei Chou et al.
Po-Wei Liao et al.
Background: Palliative chemotherapy is the preferred standard of care for patients with metastatic gastric cancer (mGC). It remains uncertain whether older patients with mGC would benefit from palliative chemotherapy. Thi...
The Relationship Between D-dimer and Prognosis in the Patients with Serum Alpha-Fetoprotein-Positive Gastric Cancer: A Retrospective Cohort Study [0.03%]
D-二聚体与血清甲胎蛋白阳性胃癌患者预后关系的队列研究
Xiaofang Zhang,Weigang Wang,Baoguo Tian et al.
Xiaofang Zhang et al.
Background: Alpha-fetoprotein-positive gastric cancer (AFPGC) is a subtype of gastric cancer that is rare in clinical practice and extremely malignant. Malignant tumors are often associated with hemorrhage, thrombosis, an...
Immunohistochemical Detection and Prognostic Significance of p53, Epidermal Growth Factor Receptor, Murine Double Minute 2, and Isocitrate Dehydrogenase 1 in Glioblastoma Multiforme Patients of Pakistan [0.03%]
巴基斯坦胶质母细胞瘤患者的免疫组化检测及预后意义-p53、表皮生长因子受体、小鼠双微体2和异柠檬酸脱氢酶1的作用
Syed Muhammad Adnan Ali,Muhammad Shahzad Shamim,Syed Ather Enam et al.
Syed Muhammad Adnan Ali et al.
Introduction: Glioblastoma multiforme (GBM) is one of the deadliest cranial tumors occurring in adults. Various biomarkers have been tested for their significance in diagnosis, prognosis, and treatment of GBM. Some well-s...
Design and Development of an Intelligent System for Predicting 5-Year Survival in Gastric Cancer [0.03%]
一种预测胃癌患者五年生存率的智能系统的设计与开发
Mohammad Reza Afrash,Mostafa Shanbehzadeh,Hadi Kazemi-Arpanahi
Mohammad Reza Afrash
Background: Gastric cancer remains one of the leading causes of worldwide cancer-specific deaths. Accurately predicting the survival likelihood of gastric cancer patients can inform caregivers to boost patient prognostica...
Pilot Study of Combination Gemogenovatucel-T (Vigil) and Durvalumab in Women With Relapsed BRCA-wt Triple-Negative Breast or Ovarian Cancer [0.03%]
用于BRCA-wt 复发三阴性乳腺癌或卵巢癌女性患者的吉莫根诺瓦塞特(VIGIL)联合度伐利尤单抗的试点研究
Minal Barve,Phylicia Aaron,Luisa Manning et al.
Minal Barve et al.
Background: Gemogenovatucel-T (Vigil) is a triple-function autologous tumor cell immunotherapy which expresses granulocyte-macrophage colony-stimulating factor and decreases expression of furin and downstream TGF-β1 and ...
Roundabout Guidance Receptor 1 Is an Emerging Prognostic Biomarker for Nasopharyngeal Carcinoma [0.03%]
圆盘引导受体1是鼻咽癌新兴的预后生物标志物
Sung-Wei Lee,Ching-Chieh Yang,Hong-Yue Lai et al.
Sung-Wei Lee et al.
Background: Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from the nasopharynx with high morbidity and mortality in Southeast Asia and south of China. Roundabout guidance receptor 1 (ROBO1) can regulate ...
GRHL2 Expression Functions in Breast Cancer Aggressiveness and Could Serve as Prognostic and Diagnostic Biomarker for Breast Cancer [0.03%]
GRHL2表达与乳腺癌的恶性程度相关并可作为诊断和预后生物标志物服务于乳腺癌诊疗
Xiaoyu Bai,Yue Li,Yanlei Li et al.
Xiaoyu Bai et al.
Background: Breast cancer (BC) is the most frequent malignancy in women worldwide and the leading cause of female cancer-associated death in the world. Grainyhead-like 2 (GRHL2) is an important gene involved in human canc...
The m6A RNA Modification Quantity and the Prognostic Effect of Reader YTHDC2 in Colorectal Cancer [0.03%]
结直肠癌中m6A修饰量及其阅读蛋白YTHDC2的预后价值
Tianyu Liu,Wentao Tang,Yijiao Chen et al.
Tianyu Liu et al.
Background: N6-methyladenosine (m6A) modification plays crucial roles in cancers. However, its alteration in colorectal cancer (CRC) is still poorly described. The purpose of this study is to explore the change of m6A mod...
Bone-Related Extramedullary Disease in Newly Diagnosed Myeloma Patients is an Independent Poor Prognostic Predictor [0.03%]
骨髓瘤患者初次诊断时与骨骼有关的髓外病变是不良预后的独立预测指标
Ying Wang,Aijun Liu,Tingting Xu et al.
Ying Wang et al.
Background: Bone-related extramedullary disease (EMD-B) is mass of clonal plasma cells derived from adjacent bone lesions and has obvious heterogeneities in clinical outcomes. This retrospective study aims to evaluate the...