CYB5R4 Gene Methylation as a Potential Epigenetic Marker for Ovarian Cancer [0.03%]
CYB5R4基因甲基化作为卵巢癌的潜在表观遗传标志物
Aysegul Gonc,Ozge Sukruoglu Erdogan,Seda Kilic Erciyas et al.
Aysegul Gonc et al.
Background: Ovarian cancer (OC) is a significant health problem often diagnosed at an advanced stage due to the lack of early symptoms and effective screening methods. This study aimed to explore the role of CYB5R4 gene m...
Antibiotic Usage During Surgery may be Correlated With Survival in Radically Resected Non-Small-Cell Lung Cancer Patients [0.03%]
手术中使用抗生素可能与根治性切除的非小细胞肺癌患者的生存率相关
Qianwen Ye,Long Liu,Meiqi Cui et al.
Qianwen Ye et al.
Background: Accumulating evidence suggests that the use of antibiotics (ATBs) is harmful to the survival of patients with non-small-cell lung cancer (NSCLC). However, the association between the prophylactic use of these ...
Evaluating Patient Adherence and Persistence to Tyrosine-Kinase Inhibitors for Metastatic Renal Cell Carcinoma: A Retrospective Analysis of Real-World Data [0.03%]
MET转移性肾细胞癌酪氨酸激酶抑制剂的患者依从性和持续性的回顾性分析:真实世界数据的评估
Zhaohui Liao Arter,David J Benjamin,Yen Cao et al.
Zhaohui Liao Arter et al.
Background: Combination therapy using an immune checkpoint inhibitor (ICI) and a tyrosine kinase inhibitor (TKI) is the standard first-line treatment for metastatic renal cell carcinoma (RCC). Oral TKIs enhance patient au...
Immunohistochemical Evaluation of SARS-CoV-2 Nucleoprotein and ACE2 Markers in Testicular Tumors Diagnosed During the COVID-19 Pandemic [0.03%]
SARS-CoV-2核蛋白和ACE2标记在COVID-19大流行期间诊断的睾丸肿瘤中的免疫组化评估
Mahi Balcı,Merva Aydemir Akkaya
Mahi Balcı
Background: The incidence of testicular tumors during the COVID-19 pandemic has raised questions about the potential impact of viral infection on tumor development. This study aimed to explore the relationship between COV...
Causal Association Between Lung Cancer and Rash: A Bidirectional Mendelian Randomization Study [0.03%]
肺癌和皮疹的因果关系:双向孟德尔随机化研究
Yang Xiao,Tian-Tian Li,Ming Li Yuan et al.
Yang Xiao et al.
Background: Skin involvement is one of the many clinical manifestations of lung cancer patients. However, there are fewer in-depth studies exploring the causal relationship between skin rashes and lung cancer subtypes, an...
Efficacy of Immunotherapy in Patients With Bone Metastases From Driver Gene-Negative Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [0.03%]
驱动基因阴性非小细胞肺癌骨转移患者免疫治疗疗效的系统评价和 meta 分析
Weixing Zhao,Xiaoni Jin,Bo Li et al.
Weixing Zhao et al.
Background: This study systematically assesses the efficacy of immunotherapy as a first-line treatment for patients with non-small-cell lung cancer (NSCLC) and bone metastases who lack driver gene mutations. This analysis...
Distribution of PAX1 and ZNF582 Hypermethylation in the Oral Exfoliated Cells of Oral Squamous Cell Carcinoma [0.03%]
口腔鳞癌患者脱落细胞中PAX1和ZNF582高甲基化分布特点
Ya-Qing Mao,Rui Sun,Shuo Liu et al.
Ya-Qing Mao et al.
Background: The DNA methylation statuses of PAX1 and ZNF582 show great promise as biomarkers for the detection of oral squamous cell carcinoma (OSCC). This study aims to investigate the distribution of PAX1 or ZNF582 meth...
Potency and Safety of KRAS G12C Inhibitors in Solid Tumors: A Systematic Review [0.03%]
KRAS G12C抑制剂在实体瘤中疗效和安全性的系统综述
Sara El Zaitouni,Abdelilah Laraqui,Youssra Boustany et al.
Sara El Zaitouni et al.
Background: The Kirsten rat sarcoma viral oncogene homolog (KRAS) gene, specifically the cysteine residue mutation KRAS (G12C), has garnered significant attention as a therapeutic target for solid cancer patients with KRA...
Prognostic Value of Tertiary Lymphoid Structures in Stage I Nonsmall Cell Lung Cancer: Does Location Matter? [0.03%]
位置影响III型淋巴器官在I期非小细胞肺癌中的预后价值吗?
Tianhui Xue,Xiaohuan Zhang,Qianwen Ye et al.
Tianhui Xue et al.
Background: Emerging evidence indicates the importance of tertiary lymphoid structures (TLSs) in predicting the outcomes of nonsmall cell lung cancer (NSCLC) patients; however, their prognostic value and correlations with...
Pain Management Adequacy in Patients With Bone Metastases: A Secondary Analysis From the Palliative Radiotherapy and Inflammation Study Trial [0.03%]
骨转移患者疼痛管理的有效性:来自姑息放疗和炎症研究试验的二次分析
Savino Cilla,Romina Rossi,Costanza Maria Donati et al.
Savino Cilla et al.
Background: Bone metastases (BMs) are a common complication in patients with cancer, often leading to significant pain that adversely affects quality of life, necessitating effective pain management strategies. This study...