Study Protocol for a Trial: A Single-Arm, Open-Labeled Study Evaluating Transcatheter Arterial Embolization Plus Everolimus Combination Therapy for Patients With Liver Metastasis of Gastroenteropancreatic Neuroendocrine Tumors [0.03%]
临床试验方案：经动脉栓塞联合依维莫司治疗胃肠胰神经内分泌肿瘤肝转移患者的单臂开放标签研究方案
Yasuto Takeuchi,Hironari Kato,Shigeru Horiguchi et al.
Yasuto Takeuchi et al.
Background: The number of patients with non-functional neuroendocrine tumors (NETs) has increased recently, and the rate of liver metastasis of NETs is about 20% in patients at the first diagnosis. Transcatheter arterial ...
First-Line Osimertinib in Patients With EGFR-Mutated Non-Small Cell Lung Cancer: Effectiveness, Resistance Mechanisms, and Prognosis of Different Subsequent Treatments [0.03%]
EGFR突变的非小细胞肺癌患者的一线奥西替尼治疗：有效性，耐药机制以及不同后续治疗的预后
Naifu Nie,Jianghua Li,Jian Zhang et al.
Naifu Nie et al.
Background: Although the clinical application of osimertinib, a third-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), has been a new step forward in the first-line treatment of non-small ...
The Association Between Gut Microbiota, Toll-Like Receptors, and Colorectal Cancer [0.03%]
肠道微生物群、 Toll样受体和结直肠癌之间的关联
Yongkun Fang,Cheng Yan,Qi Zhao et al.
Yongkun Fang et al.
The large number of microbes found in the gut are involved in various critical biological processes in the human body and have dynamic and complex interactions with the immune system. Disruptions in the host's gut microbiota and the metabol...
Cancer Biomarkers in Liquid Biopsy for Early Detection of Breast Cancer: A Systematic Review [0.03%]
液体活检中用于早期检测乳腺癌的癌症生物标志物的系统性回顾
Galo Duque,Carlos Manterola,Tamara Otzen et al.
Galo Duque et al.
Background: Breast cancer (BC) is the most common neoplasm in women worldwide. Liquid biopsy (LB) is a non-invasive diagnostic technique that allows the analysis of biomarkers in different body fluids, particularly in per...
Concordance of Genomic Profiles in Matched Tissue and Plasma Samples From Chinese Patients With Lung Cancer [0.03%]
中国肺癌患者组织和血浆样本的基因组谱一致性分析结果显示
Yueming He,Weifeng Guo,Meng Xu et al.
Yueming He et al.
Background: Next-generation sequencing (NGS) has been widely used to identify targetable variants for patients with solid tumors, especially lung cancer. Circulating tumor DNA (ctDNA) has emerged as an alternative approac...
Effect of Number of Retrieved Lymph Nodes on Prognosis in FIGO Stage IA1-IIA2 Cervical Cancer Patients Treated With Primary Radical Surgery [0.03%]
术前根治手术治疗FIGOⅠA1～ⅡA2期宫颈癌患者淋巴结取材数目对其预后的影响
Shan Jiang,Peng Jiang,Tingting Jiang et al.
Shan Jiang et al.
Background: The influence of the number of removed lymph nodes (RLNs) on patients with early-stage cervical cancer (ESCC) is still questionable. The objective of this study was to explore the prognostic value of RLNs on E...
Preoperative Absolute Lymphocyte Count to Carcinoembryonic Antigen Ratio Is a Superior Predictor of Survival in Stage I to III Colorectal Cancer [0.03%]
术前淋巴细胞绝对计数与癌胚抗原比值可更优预测结直肠癌I至III期患者的生存率
Yue Zhou,Fei Cheng,Zihao Zhang et al.
Yue Zhou et al.
Background: Preoperative absolute lymphocyte count (ALC) and carcinoembryonic antigen (CEA) are useful prognostic indicators in colorectal cancer (CRC); however, the role of the ALC-to-CEA ratio (LCR) has been less addres...
Immunotherapy With Checkpoint Inhibitors in FGFR-Altered Urothelial Carcinoma [0.03%]
FGFR变异尿路上皮癌的免疫检查点抑制剂治疗
David J Benjamin,Nataliya Mar,Arash Rezazadeh Kalebasty
David J Benjamin
The treatment landscape of metastatic urothelial cancer (mUC) remained unchanged for over 30 years until the approval of immune checkpoint inhibitors (ICIs) in 2016. Since then, several ICIs have been approved for the treatment of mUC. In a...
Prognostic Values From Integrated Analysis of the Nomogram Based on RNA-Binding Proteins and Clinical Factors in Endometrial Cancer [0.03%]
基于RNA结合蛋白和临床因素的整合 nomogram 评估内膜癌预后的价值
Shuang Yuan,Xiao Sun,Lihua Wang
Shuang Yuan
Background: Endometrial cancer (EC) is a common gynecological malignancy, and the prognosis of advanced EC is unsatisfactory. The deregulated expression of RNA-binding proteins (RBPs) is closely associated with the occurr...
Changes in Behavior After Vaccination and Opinions Toward Mask Wearing: Thoracic Oncology Patient-Reported Experiences During the COVID-19 Pandemic [0.03%]
新冠疫情下胸部肿瘤患者的疫苗接种后的行为变化及对佩戴口罩的看法
Toki Bolt,Amanda Tufman,Laura Sellmer et al.
Toki Bolt et al.
Background: The COVID-19 vaccines, face masks, and social distancing are effective interventions to prevent SARS-CoV-2 infections. In this study, we aimed to determine lung cancer patients' attitudes toward vaccination, c...