Appropriate treatment of acute otitis media in the era of antibiotic resistance [0.03%]
抗生素耐药时代的急性中耳炎合理治疗
Ron Dagan
Ron Dagan
The outcome of treatment for acute otitis media (AOM) differs between various antibiotic drugs. Outcome depends upon the drugs' pharmacokinetics, but in the case of infectious diseases also on the susceptibility of the organism and the inte...
Alberto Verrotti,Ebe D&#x;Adamo,Pasquale Parisi et al.
Alberto Verrotti et al.
Levetiracetam is an antiepileptic drug that has been shown to be effective in various types of seizures, both partial and generalized. Although it is not yet well established because of the small number of studies, levetiracetam as both add...
Impact of antiretroviral therapy on growth, body composition and metabolism in pediatric HIV patients [0.03%]
抗逆转录病毒治疗对儿科HIV患者生长、体成分和代谢的影响
Roy J Kim,Richard M Rutstein
Roy J Kim
Highly active antiretroviral therapy improves survival and growth in children with HIV infection. However, its use can be associated with adverse changes in body composition and metabolism. Bone mineral density can be adversely affected in ...
Cardiovascular effects of medications for the treatment of attention-deficit hyperactivity disorder: what is known and how should it influence prescribing in children? [0.03%]
注意缺陷多动障碍治疗药物的心血管作用及对儿童处方的影响：已有认识与未来方向
Josephine Elia,Victoria L Vetter
Josephine Elia
The effective medications currently marketed for attention-deficit hyperactivity disorder (ADHD) have central and peripheral catecholaminergic effects that have been shown to result in statistically significant increases in heart rate and b...
Escitalopram: in the treatment of major depressive disorder in adolescent patients [0.03%]
艾司西酞普兰治疗青少年重度抑郁障碍患者
Lily P H Yang,Lesley J Scott
Lily P H Yang
Escitalopram is a selective serotonin reuptake inhibitor (SSRI), and is the second antidepressant to be approved for use in treating major depressive disorder (MDD) in adolescent patients (aged 12-17 years) in the US. In a randomized, doubl...
James E Frampton
James E Frampton
Mifamurtide (liposomal muramyl tripeptide phosphatidyl ethanolamine; Mepact) is an immunomodulator with antitumor effects that appear to be mediated via activation of monocytes and macrophages. In the EU, mifamurtide is indicated in childre...
Oral olanzapine disposition in adolescents with schizophrenia or bipolar I disorder: a population pharmacokinetic model [0.03%]
青少年精神分裂症或I型双相情感障碍患者的奥氮平药代动力学行为：群体药代动力学模型分析
Evelyn D Lobo,Carol Robertson-Plouch,Tonya Quinlan et al.
Evelyn D Lobo et al.
Background: Olanzapine is an atypical antipsychotic approved for the treatment of adults and adolescents (aged 13 -17 years) with schizophrenia or bipolar I disorder (manic or mixed episodes). ...
Colesevelam: in pediatric patients with heterozygous familial hypercholesterolemia [0.03%]
考来色韦用于杂合子家族性高胆固醇血症患儿
Caroline M Perry
Caroline M Perry
Colesevelam hydrochloride (colesevelam), a non-absorbed, synthetic, lipid-lowering polymer, is a bile acid sequestrant. Colesevelam binds with high affinity to bile acids within the gastrointestinal tract, thereby inhibiting the reabsorptio...
Darunavir: in treatment-experienced pediatric patients with HIV-1 infection [0.03%]
达芦那韦：治疗接受过多种方案的儿科HIV-1感染患者的疗效
Kate McKeage,Lesley J Scott
Kate McKeage
Darunavir is a nonpeptidic HIV type 1 (HIV-1) protease inhibitor (PI) that binds with high affinity to the HIV-1 protease, including multi-drug resistant proteases. This drug is highly potent against a range of laboratory strains and clinic...