Hannah A Blair
Hannah A Blair
Copper histidinate (ZYCUBO®) is a bioavailable copper replacement therapy developed by Cyprium Therapeutics and Sentynl Therapeutics for the treatment of Menkes disease, a genetic disorder caused by variants in the copper transporter gene,...
Long-Term Safety and Efficacy of Dupilumab Treatment in Children Aged 6 Months to 5 Years with Severe Atopic Dermatitis [0.03%]
dupilumab治疗6月龄至5岁重度特应性皮炎儿童长期安全性和有效性的研究
Amy S Paller,Andreas Pinter,Lara Wine Lee et al.
Amy S Paller et al.
Background: Infants and young children with severe atopic dermatitis (AD) have a high burden of disease with a strong impact on quality of life. Here we assess long-term efficacy and safety of dupilumab in pediatric patie...
GLP-1 Receptor Agonist Use Across Preconception, Pregnancy, and the Postpartum Periods [0.03%]
妊娠前后胰高血糖素样肽-1受体激动剂的使用
Florence Porterfield,Serena Michelle Ogunwole,Jacqueline Maya et al.
Florence Porterfield et al.
Obesity in reproductive-age women is associated with increased risk of cardiometabolic disease, infertility, and pregnancy-related complications affecting both the mother and fetus. Recently, the introduction of highly effective glucagon-li...
Ahmed Naguy,Bibi Alamiri
Ahmed Naguy
Editorial
Paediatric drugs. 2026 Apr 1. DOI:10.1007/s40272-026-00749-2 2026
Susan J Keam
Susan J Keam
Ferric maltol (ACCRUFeR®), is an oral iron replacement product being developed by Shield Therapeutics plc for the treatment of iron deficiency (ID). Ferric maltol was originally approved for the treatment of iron deficiency anemia (IDA) in...
Fixed Dosing of Leuprolide Acetate, a GnRH Agonist, in Children with Central Precocious Puberty: A Population Pharmacokinetic Justification [0.03%]
用于儿童中枢性早熟的亮丙瑞林（一种GnRH激动剂）固定剂量用药：基于人群药代动力学的依据
Chay Ngee Lim,Omar N Al Yacoub,Nael M Mostafa et al.
Chay Ngee Lim et al.
Background: Central precocious puberty is the early onset of puberty due to premature activation of the hypothalamic-pituitary-gonadal axis, which can reduce adult height. Leuprolide, a gonadotropin-releasing hormone agon...
Effect of Lactoferrin in Obese Children and Adolescents with Metabolic Dysfunction-Associated Steatotic Disease: A Randomized Controlled Study [0.03%]
乳铁蛋白对代谢功能障碍相关脂肪性肝病儿童和青少年疗效的随机对照研究
Doaa El Amrousy,Dalia El-Afify,Esraa Abd Al-Fattah Sorour et al.
Doaa El Amrousy et al.
Background and objective: Lactoferrin is an iron-binding glycoprotein existing in mammalian milk. It has immunomodulatory, antioxidant, and anti-inflammatory properties, and it can also regulate metabolism. The present st...
Philippe Van de Perre,Nicolas Meda,Souleymane Tassembedo et al.
Philippe Van de Perre et al.
Despite considerable progress in preventing mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV), eliminating paediatric HIV has not been achieved. Extended postnatal prophylaxis (ePNP), defined as prophylaxis administ...
Julia Sessions,Maureen Bauer,Calies Menard-Katcher et al.
Julia Sessions et al.
Eosinophilic esophagitis is a chronic immune-mediated inflammatory disorder of the esophagus comprising symptoms of esophageal dysfunction with eosinophilic inflammation. The diagnosis is based on histopathologic criteria with elevated esop...
Shuo Xu,Jennifer Foster,Andrew Wahba
Shuo Xu
High-risk neuroblastoma (HRNB) accounts for a disproportionately high percentage of cancer-related deaths among pediatric patients, despite intensive multimodal treatment. Current frontline therapy comprising chemotherapy, surgery, autologo...